Phenotype measures set

ID, description, units MPD:9905   non-HDL cholesterol   [mg/dL]
high-fat diet study
Measures • baseline    • after 17wks on diet    • Δchange
Data set, strains Paigen2   inbred w/CC7   41 strains     sex: both     age: 7-9wks
Procedure lipid profile
Comparisonrepeated measures, baseline then treated, same cohort
Ontology mappings



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Paigen2 - non-HDL cholesterol

Female

Male



  RM-ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 7458.0016 7458.0016 1.831 0.1766
between   strain 32 2120459.8741 66264.3711 16.2683 < 0.0001
between   sex:strain 32 258153.7634 8067.3051 1.9806 0.0013
between   Residuals 495 2016245.1596 4073.2225
within   group 1 4573392.9242 4573392.9242 1177.3163 < 0.0001
within   group:sex 1 5824.1808 5824.1808 1.4993 0.2214
within   group:strain 32 2135674.1911 66739.8185 17.1807 < 0.0001
within   group:sex:strain 32 268953.5284 8404.7978 2.1636 0.0003
within   Residuals 495 1922872.7977 3884.5915

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelNo.
strains
SexAge
Paigen2 9905 lipid profile high-fat diet non-HDL cholesterol   [mg/dL]   baseline   nonHDL inbred w/CC7 41 both 7-9wks
Paigen2 9908 lipid profile high-fat diet non-HDL cholesterol   [mg/dL]   after 17wks on diet   nonHDL_fat17 inbred w/CC7 41 both 7-9wks
Paigen2 9911 lipid profile high-fat diet non-HDL cholesterol   [mg/dL]   fold change   nonHDL_chg inbred w/CC7 41 both 7-9wks (not included in the analysis / display)