Project measure / variable:   Paigen2   nonHDL_chg

ID, description, units MPD:9911   nonHDL_chg   non-HDL cholesterol (plasma)   [mg/dL]  fold change  
high-fat diet study
Data set, strains Paigen2   inbred w/CC7   41 strains     sex: both     age: 7-9wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen2 - non-HDL cholesterol (plasma) fold change



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains34 strains
Mean of the strain means10.8   mg/dL 11.0   mg/dL
Median of the strain means7.64   mg/dL 5.74   mg/dL
SD of the strain means± 10.2 ± 10.6
Coefficient of variation (CV)0.946 0.958
Min–max range of strain means1.13   –   50.2   mg/dL 1.62   –   43.3   mg/dL
Mean sample size per strain7.9   mice 7.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.6809 1.6809 0.0056 0.9402
strain 32 37577.3895 1174.2934 3.9314 < 0.0001
sex:strain 32 9891.2362 309.1011 1.0348 0.4179
Residuals 438 130828.7294 298.6957


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.5 0.728   10 0.23 0.292 1.63, 3.8 -0.81
129S1/SvImJ m 2.68 1.64   9 0.546 0.611 0.98, 6.33 -0.79
A/J f 20.5 8.7   10 2.75 0.424 8.48, 39.5 0.96
A/J m 43.3 74.1   7 28.0 1.71 9.61, 211.0 3.05
AKR/J f 3.32 3.63   12 1.05 1.1 0.936, 14.3 -0.73
BALB/cByJ f 4.56 3.36   9 1.12 0.737 1.01, 10.7 -0.61
BALB/cByJ m 4.35 1.06   6 0.433 0.244 3.22, 6.06 -0.63
BTBR T+ Itpr3tf/J f 6.7 5.7   8 2.02 0.851 3.13, 20.2 -0.4
BTBR T+ Itpr3tf/J m 21.3 31.7   7 12.0 1.49 3.36, 89.4 0.97
BUB/BnJ f 24.1 27.0   10 8.53 1.12 2.36, 95.0 1.31
BUB/BnJ m 3.8 1.76   4 0.88 0.463 1.85, 6.08 -0.68
C3H/HeJ f 10.7 7.53   9 2.51 0.703 2.02, 26.2 -0.01
C3H/HeJ m 4.25 3.3   7 1.25 0.777 0.146, 10.0 -0.64
C57BL/10J f 3.23 0.937   9 0.312 0.29 1.85, 5.2 -0.74
C57BL/10J m 3.97 2.61   9 0.871 0.657 1.12, 7.57 -0.67
C57BL/6J f 5.73 2.99   10 0.946 0.522 1.92, 11.4 -0.49
C57BL/6J m 5.89 3.94   10 1.25 0.668 1.1, 15.4 -0.49
C57BLKS/J f 10.5 11.8   9 3.94 1.12 2.3, 40.9 -0.03
C57BR/cdJ f 12.4 5.33   10 1.68 0.431 8.61, 25.9 0.16
C57BR/cdJ m 13.3 17.9   9 5.96 1.34 2.42, 59.1 0.21
C57L/J f 5.13 4.2   10 1.33 0.818 2.71, 16.9 -0.55
C57L/J m 7.51 4.07   9 1.36 0.542 2.47, 16.4 -0.33
C58/J f 18.2 11.5   5 5.13 0.63 6.36, 32.5 0.73
C58/J m 16.1 8.98   5 4.02 0.558 4.95, 28.6 0.48
CAST/EiJ f 15.4 9.22   9 3.07 0.599 7.58, 35.7 0.45
CAST/EiJ m 11.7 8.59   8 3.04 0.732 3.97, 25.6 0.06
CBA/J f 10.2 14.2   7 5.38 1.4 1.88, 42.0 -0.06
CBA/J m 2.91 1.93   8 0.681 0.661 0.747, 6.45 -0.77
CZECHII/EiJ f 4.66 4.22   9 1.41 0.904 0.474, 14.8 -0.6
CZECHII/EiJ m 3.69 2.36   7 0.892 0.64 0.688, 6.5 -0.7
DBA/1J f 8.09 12.0   5 5.39 1.49 0.438, 29.5 -0.26
DBA/1J m 1.62 0.837   6 0.342 0.518 0.799, 2.82 -0.89
DBA/2J f 1.13 0.625   9 0.208 0.552 0.218, 2.04 -0.95
DBA/2J m 1.75 0.855   9 0.285 0.489 0.828, 3.33 -0.88
FVB/NJ f 2.89 1.65   8 0.583 0.57 1.32, 6.0 -0.77
FVB/NJ m 6.28 0.709   4 0.354 0.113 5.5, 7.22 -0.45
I/LnJ f 16.5 6.58   5 2.94 0.399 8.43, 26.3 0.56
JF1/MsJ f 4.16 2.13   10 0.675 0.513 1.29, 8.77 -0.65
JF1/MsJ m 8.3 6.16   7 2.33 0.742 2.59, 20.3 -0.26
KK/HlJ f 1.78 0.794   5 0.355 0.447 0.677, 2.9 -0.88
LP/J f 4.75 5.49   9 1.83 1.16 0.835, 14.6 -0.59
LP/J m 4.98 5.42   7 2.05 1.09 0.3, 16.4 -0.57
MA/MyJ f 7.85 3.93   10 1.24 0.5 3.9, 16.5 -0.29
MA/MyJ m 3.85 1.38   10 0.435 0.357 2.6, 7.21 -0.68
MOLF/EiJ f 33.1 16.3   6 6.66 0.493 10.7, 59.8 2.19
MSM/MsJ f 1.16 0.508   4 0.254 0.439 0.593, 1.69 -0.94
MSM/MsJ m 4.02 2.89   8 1.02 0.719 1.29, 8.67 -0.66
NOD/ShiLtJ f 7.69 2.39   5 1.07 0.311 5.2, 10.8 -0.3
NOD/ShiLtJ m 13.9 12.0   2   8.47 0.86 5.45, 22.4 0.27
NON/ShiLtJ f 14.7 9.81   9 3.27 0.668 5.77, 39.7 0.39
NON/ShiLtJ m 5.58 2.18   12 0.628 0.39 2.29, 8.55 -0.52
NZB/BlNJ f 7.3 11.3   10 3.57 1.55 1.87, 39.2 -0.34
NZB/BlNJ m 12.9 8.43   8 2.98 0.654 4.67, 31.2 0.18
NZW/LacJ f 15.3 26.6   8 9.42 1.74 2.34, 81.0 0.44
NZW/LacJ m 3.53 2.46   7 0.929 0.696 1.56, 8.4 -0.71
PERA/EiJ f 11.2 9.85   3 5.69 0.88 3.66, 22.3 0.04
PERA/EiJ m 33.4 25.9   5 11.6 0.773 11.5, 63.7 2.11
PL/J f 4.56 2.54   10 0.802 0.557 1.38, 8.34 -0.61
PWK/PhJ m 4.19 1.78   7 0.672 0.424 2.04, 6.78 -0.65
RF/J f 4.7 6.2   5 2.77 1.32 1.47, 15.8 -0.6
RIIIS/J f 34.5 22.8   6 9.32 0.662 9.08, 64.5 2.33
RIIIS/J m 32.7 60.1   8 21.2 1.84 2.82, 180.0 2.05
SEA/GnJ f 3.99 1.82   8 0.643 0.456 1.76, 7.7 -0.67
SEA/GnJ m 12.3 13.9   6 5.69 1.14 3.45, 40.2 0.12
SJL/J f 2.27 0.798   9 0.266 0.352 0.75, 3.3 -0.83
SJL/J m 5.6 3.44   12 0.993 0.614 0.806, 12.2 -0.51
SM/J f 11.6 4.48   8 1.58 0.386 6.51, 20.0 0.08
SM/J m 18.8 23.0   9 7.67 1.22 1.8, 73.7 0.73
SPRET/EiJ f 7.6 7.42   4 3.71 0.977 0.918, 16.2 -0.31
SPRET/EiJ m 24.5 29.9   2   21.2 1.22 3.33, 45.7 1.27
SWR/J f 15.9 20.0   7 7.56 1.26 3.43, 56.7 0.5
SWR/J m 3.83 3.05   7 1.15 0.797 1.8, 10.5 -0.68
WSB/EiJ f 50.2 69.2   6 28.2 1.38 4.22, 186.0 3.87
WSB/EiJ m 28.6 26.0   7 9.84 0.912 4.39, 67.5 1.66


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.4975 5.4653 13.2389 0.0
129S1/SvImJ m 2.6818 5.7609 14.0043 0.0
A/J f 20.5138 5.4653 31.2553 9.7723
A/J m 43.2778 6.5323 56.1164 30.4393
BALB/cByJ f 4.5614 5.7609 15.884 0.0
BALB/cByJ m 4.3486 7.0557 18.2158 0.0
BTBR T+ Itpr3tf/J f 6.6975 6.1104 18.7068 0.0
BTBR T+ Itpr3tf/J m 21.281 6.5323 34.1195 8.4425
BUB/BnJ f 24.1485 5.4653 34.89 13.407
BUB/BnJ m 3.7991 8.6414 20.7829 0.0
C3H/HeJ f 10.7224 5.7609 22.0449 0.0
C3H/HeJ m 4.2481 6.5323 17.0866 0.0
C57BL/10J f 3.2322 5.7609 14.5547 0.0
C57BL/10J m 3.9739 5.7609 15.2964 0.0
C57BL/6J f 5.7315 5.4653 16.473 0.0
C57BL/6J m 5.8942 5.4653 16.6357 0.0
C57BR/cdJ f 12.3567 5.4653 23.0982 1.6153
C57BR/cdJ m 13.3311 5.7609 24.6536 2.0086
C57L/J f 5.1318 5.4653 15.8733 0.0
C57L/J m 7.5058 5.7609 18.8284 0.0
C58/J f 18.188 7.7291 33.3788 2.9972
C58/J m 16.0892 7.7291 31.2799 0.8984
CAST/EiJ f 15.3949 5.7609 26.7174 4.0724
CAST/EiJ m 11.7378 6.1104 23.7471 0.0
CBA/J f 10.1947 6.5323 23.0333 0.0
CBA/J m 2.9132 6.1104 14.9226 0.0
CZECHII/EiJ f 4.6641 5.7609 15.9866 0.0
CZECHII/EiJ m 3.6918 6.5323 16.5303 0.0
DBA/1J f 8.0946 7.7291 23.2853 0.0
DBA/1J m 1.616 7.0557 15.4832 0.0
DBA/2J f 1.1315 5.7609 12.454 0.0
DBA/2J m 1.7467 5.7609 13.0693 0.0
FVB/NJ f 2.8902 6.1104 14.8996 0.0
FVB/NJ m 6.2809 8.6414 23.2647 0.0
JF1/MsJ f 4.1626 5.4653 14.9041 0.0
JF1/MsJ m 8.3013 6.5323 21.1398 0.0
LP/J f 4.7529 5.7609 16.0754 0.0
LP/J m 4.979 6.5323 17.8176 0.0
MA/MyJ f 7.8504 5.4653 18.5919 0.0
MA/MyJ m 3.8544 5.4653 14.5959 0.0
MSM/MsJ f 1.1587 8.6414 18.1424 0.0
MSM/MsJ m 4.0232 6.1104 16.0325 0.0
NOD/ShiLtJ f 7.6859 7.7291 22.8766 0.0
NOD/ShiLtJ m 13.9165 12.2208 37.9352 0.0
NON/ShiLtJ f 14.6829 5.7609 26.0054 3.3604
NON/ShiLtJ m 5.5828 4.9891 15.3883 0.0
NZB/BlNJ f 7.2976 5.4653 18.039 0.0
NZB/BlNJ m 12.9 6.1104 24.9093 0.8907
NZW/LacJ f 15.3406 6.1104 27.3499 3.3312
NZW/LacJ m 3.5289 6.5323 16.3674 0.0
PERA/EiJ f 11.187 9.9782 30.7982 0.0
PERA/EiJ m 33.4424 7.7291 48.6332 18.2517
RIIIS/J f 34.479 7.0557 48.3462 20.6118
RIIIS/J m 32.722 6.1104 44.7313 20.7126
SEA/GnJ f 3.9892 6.1104 15.9985 0.0
SEA/GnJ m 12.2592 7.0557 26.1264 0.0
SJL/J f 2.2706 5.7609 13.5931 0.0
SJL/J m 5.5998 4.9891 15.4054 0.0
SM/J f 11.6141 6.1104 23.6235 0.0
SM/J m 18.8187 5.7609 30.1412 7.4962
SPRET/EiJ f 7.5986 8.6414 24.5824 0.0
SPRET/EiJ m 24.5 12.2208 48.5187 0.4813
SWR/J f 15.8767 6.5323 28.7153 3.0382
SWR/J m 3.8283 6.5323 16.6669 0.0
WSB/EiJ f 50.1796 7.0557 64.0468 36.3124
WSB/EiJ m 28.5511 6.5323 41.3896 15.7126


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.5896 3.9705 10.3931 0.0
A/J both 31.8958 4.2585 40.2655 23.5261
BALB/cByJ both 4.455 4.5544 13.4063 0.0
BTBR T+ Itpr3tf/J both 13.9892 4.4724 22.7792 5.1993
BUB/BnJ both 13.9738 5.1123 24.0215 3.9261
C3H/HeJ both 7.4853 4.3549 16.0443 0.0
C57BL/10J both 3.6031 4.0736 11.6093 0.0
C57BL/6J both 5.8129 3.8646 13.4082 0.0
C57BR/cdJ both 12.8439 3.9705 20.6474 5.0404
C57L/J both 6.3188 3.9705 14.1223 0.0
C58/J both 17.1386 5.4653 27.8801 6.3971
CAST/EiJ both 13.5663 4.199 21.819 5.3137
CBA/J both 6.554 4.4724 15.3439 0.0
CZECHII/EiJ both 4.1779 4.3549 12.7369 0.0
DBA/1J both 4.8553 5.2326 15.1395 0.0
DBA/2J both 1.4391 4.0736 9.4453 0.0
FVB/NJ both 4.5856 5.2918 14.986 0.0
JF1/MsJ both 6.232 4.2585 14.6017 0.0
LP/J both 4.866 4.3549 13.425 0.0
MA/MyJ both 5.8524 3.8646 13.4478 0.0
MSM/MsJ both 2.5909 5.2918 12.9913 0.0
NOD/ShiLtJ both 10.8012 7.2299 25.0108 0.0
NON/ShiLtJ both 10.1328 3.8105 17.622 2.6437
NZB/BlNJ both 10.0988 4.099 18.1549 2.0427
NZW/LacJ both 9.4347 4.4724 18.2247 0.6448
PERA/EiJ both 22.3147 6.3108 34.7179 9.9115
RIIIS/J both 33.6005 4.6669 42.7728 24.4282
SEA/GnJ both 8.1242 4.6669 17.2965 0.0
SJL/J both 3.9352 3.8105 11.4243 0.0
SM/J both 15.2164 4.199 23.469 6.9638
SPRET/EiJ both 16.0493 7.4837 30.7577 1.3409
SWR/J both 9.8525 4.619 18.9308 0.7743
WSB/EiJ both 39.3654 4.8076 48.8143 29.9165




  GWAS USING LINEAR MIXED MODELS