Project measure / variable:   Schwartz2   pctEOS_ova48

ID, description, units MPD:9808   pctEOS_ova48   alveolar eosinophils (percentage of total lavage cells), 48h post-challenge   [%]  OVA-sensitized  
ovalbumin study
Data set, strains Schwartz2   inbred   8 strains     sex: m     age: 6-8wks
Procedure bronchoalveolar lavage assessment
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  STRAIN COMPARISON PLOT
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Schwartz2 - alveolar eosinophils (percentage of total lavage cells), 48h post-challenge OVA-sensitized



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means39.2   %
Median of the strain means31.2   %
SD of the strain means± 22.7
Coefficient of variation (CV)0.578
Min–max range of strain means14.0   –   76.9   %
Mean sample size per strain4.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 16544.0356 2363.4337 7.5262 < 0.0001
Residuals 31 9734.8875 314.0286


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 76.9 8.63   4 4.32 0.112 64.5, 83.5 1.66
A/J m 36.8 12.6   5 5.62 0.341 24.0, 52.0 -0.11
BALB/cJ m 18.8 14.8   5 6.61 0.786 1.0, 35.0 -0.9
BTBR T+ Itpr3tf/J m 14.0 13.1   5 5.84 0.933 -1.11
C3H/HeJ m 25.6 12.8   5 5.71 0.499 14.0, 44.0 -0.6
C57BL/6J m 25.2 20.4   5 9.14 0.811 -0.62
DBA/2J m 60.8 32.7   5 14.6 0.538 5.0, 90.0 0.95
FVB/NJ m 55.8 13.4   5 5.99 0.24 45.0, 79.0 0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 76.875 8.8604 94.946 58.804
A/J m 36.8 7.925 52.9632 20.6368
BALB/cJ m 18.8 7.925 34.9632 2.6368
BTBR T+ Itpr3tf/J m 14.0 7.925 30.1632 0.0
C3H/HeJ m 25.6 7.925 41.7632 9.4368
C57BL/6J m 25.2 7.925 41.3632 9.0368
DBA/2J m 60.8 7.925 76.9632 44.6368
FVB/NJ m 55.8 7.925 71.9632 39.6368




  GWAS USING LINEAR MIXED MODELS