MPD: Project measures / variables set: GMC16 ALP

Project measures / variables set: GMC16 ALP

ID, description, units	MPD:56526 ALP alkaline phosphatase (plasma ALP) [IU/L]
Measures	• age 16-17wks • 20-21wks
Data set, strains	GMC16 inbred w/CC8 8 strains sex: both
Procedure	metabolic panel
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0000202 blood alkaline phosphatase amount MA:0002501 plasma MP:0000202 abnormal circulating alkaline phosphatase level

Values Means Δ Means Z-scores

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GMC16 - alkaline phosphatase (plasma ALP)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	10737.4824	10737.4824	5.6231	0.0192
sex	1	48842.6797	48842.6797	25.5782	< 0.0001
strain	4	45531.8688	11382.9672	5.9611	0.0002
age:sex	1	4247.0026	4247.0026	2.2241	0.1383
age:strain	4	6374.9095	1593.7274	0.8346	0.5056
sex:strain	4	33802.3262	8450.5815	4.4255	0.0022
age:sex:strain	4	2265.8893	566.4723	0.2967	0.8797
Residuals	128	244421.1591	1909.5403

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
GMC16	56526	metabolic panel	(none)	alkaline phosphatase (plasma ALP) [IU/L] at age 16-17wks ALP_17	inbred w/CC8	7	both	16-17wks
GMC16	56527	metabolic panel	(none)	alkaline phosphatase (plasma ALP) [IU/L] at age 20-21wks ALP_21	inbred w/CC8	8	both	20-21wks