Project measure / variable:   GMC16   ALP_17

ID, description, units MPD:56526   ALP_17   alkaline phosphatase (plasma ALP)   [IU/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - alkaline phosphatase (plasma ALP) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means137   IU/L 110   IU/L
Median of the strain means144   IU/L 99.8   IU/L
SD of the strain means± 37.4 ± 58.3
Coefficient of variation (CV)0.273 0.529
Min–max range of strain means68.5   –   173   IU/L 63.8   –   235   IU/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 29484.9 29484.9 74.2942 < 0.0001
strain 4 20964.4 5241.1 13.2062 < 0.0001
sex:strain 4 12559.1 3139.775 7.9114 0.0002
Residuals 30 11906.0 396.8667


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 162.0 30.6   4 15.3 0.189 119.0, 184.0 0.67
129S1/SvImJ m 91.5 6.61   4 3.3 0.0722 84.0, 98.0 -0.32
A/J f 134.0 11.5   4 5.75 0.0862 121.0, 146.0 -0.08
A/J m 102.0 1.89   4 0.946 0.0186 99.0, 103.0 -0.14
C57BL/6J f 155.0 8.76   4 4.38 0.0565 143.0, 164.0 0.48
C57BL/6J m 99.8 9.43   4 4.71 0.0945 93.0, 113.0 -0.18
NOD/ShiLtJ f 173.0 38.3   4 19.1 0.221 121.0, 213.0 0.96
NOD/ShiLtJ m 63.8 5.19   4 2.59 0.0814 59.0, 70.0 -0.8
NZO/HlLtJ f 68.5 3.32   4 1.66 0.0484 64.0, 71.0 -1.83
NZO/HlLtJ m 64.0 34.4   4 17.2 0.537 42.0, 115.0 -0.79
PWK/PhJ m 235.0 0.0   1   0.0 0.0 235.0, 235.0 2.14
WSB/EiJ f 129.0 0.0   1   0.0 0.0 129.0, 129.0 -0.21
WSB/EiJ m 116.0 8.19   3 4.73 0.0706 109.0, 125.0 0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 162.25 9.9608 182.5926 141.9074
129S1/SvImJ m 91.5 9.9608 111.8426 71.1574
A/J f 133.5 9.9608 153.8426 113.1574
A/J m 101.75 9.9608 122.0926 81.4074
C57BL/6J f 155.0 9.9608 175.3426 134.6574
C57BL/6J m 99.75 9.9608 120.0926 79.4074
NOD/ShiLtJ f 173.0 9.9608 193.3426 152.6574
NOD/ShiLtJ m 63.75 9.9608 84.0926 43.4074
NZO/HlLtJ f 68.5 9.9608 88.8426 48.1574
NZO/HlLtJ m 64.0 9.9608 84.3426 43.6574


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 126.875 7.0433 141.2594 112.4906
A/J both 117.625 7.0433 132.0094 103.2406
C57BL/6J both 127.375 7.0433 141.7594 112.9906
NOD/ShiLtJ both 118.375 7.0433 132.7594 103.9906
NZO/HlLtJ both 66.25 7.0433 80.6344 51.8656




  GWAS USING LINEAR MIXED MODELS