Project measures / variables set:   Wiltshire4   monocytes_BEZ

ID, description, units MPD:52413   monocytes_BEZ   monocytes, percent viability   [%]  
BEZ235 study
Measures
• dose [µM]:    • control    • 0.046    • 0.137    • 1.235    • 11.1    • 100
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Wiltshire4 - monocytes, percent viability




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 5 42200.3415 8440.0683 50.2473 < 0.0001
strain 33 99123.1556 3003.732 17.8825 < 0.0001
dose:strain 165 105247.2014 637.8618 3.7975 < 0.0001
Residuals 594 99774.5843 167.9707

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Wiltshire4 52413 immune cell quantification BEZ235 monocytes, percent viability   [%]   control  monocytes_BEZ_ctrl inbred w/CC7 34 m 10wks
Wiltshire4 52414 immune cell quantification BEZ235 monocytes, percent viability   [%]   dose: 0.046 µM  monocytes_BEZ_A inbred w/CC7 34 m 10wks
Wiltshire4 52415 immune cell quantification BEZ235 monocytes, percent viability   [%]   dose: 0.137 µM  monocytes_BEZ_B inbred w/CC7 34 m 10wks
Wiltshire4 52416 immune cell quantification BEZ235 monocytes, percent viability   [%]   dose: 1.235 µM  monocytes_BEZ_C inbred w/CC7 34 m 10wks
Wiltshire4 52417 immune cell quantification BEZ235 monocytes, percent viability   [%]   dose: 11.1 µM  monocytes_BEZ_D inbred w/CC7 34 m 10wks
Wiltshire4 52418 immune cell quantification BEZ235 monocytes, percent viability   [%]   dose: 100 µM  monocytes_BEZ_E inbred w/CC7 34 m 10wks