MPD: Project measures / variables set: Boon1 bw

Project measures / variables set: Boon1 bw_change

ID, description, units	MPD:46911 bw_change change in body weight, post-infection [%] influenza A (H5N1) virus study
Measures	• dosage group: • low • medium • high
Data set, strains	Boon1 inbred 23 strains sex: f age: 6-9wks
Procedure	body weight
Comparison	multiple dosage cohorts but no control group
Ontology mappings	VT:0001259 body mass VT:0010439 response to viral infection trait MP:0001259 abnormal body weight MP:0020185 altered susceptibility to viral infection

Values Means Δ Means Z-scores

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Boon1 - change in body weight, post-infection

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	2	30204.5974	15102.2987	225.2014	< 0.0001
strain	15	19497.2546	1299.817	19.3825	< 0.0001
dose:strain	30	12013.6344	400.4545	5.9715	< 0.0001
Residuals	706	47345.2739	67.0613

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Boon1	46911	body weight	influenza A (H5N1) virus	change in body weight, post-infection [%] dose group: low bw_change_lo	inbred	18	f	6-9wks
Boon1	46912	body weight	influenza A (H5N1) virus	change in body weight, post-infection [%] dose group: medium bw_change_med	inbred	22	f	6-9wks
Boon1	46913	body weight	influenza A (H5N1) virus	change in body weight, post-infection [%] dose group: high bw_change_hi	inbred	21	f	6-9wks