Boon1: Susceptibility to influenza A (H5N1) viral infection in females of 23 strains of mice (2011)

Boon AC, Finkelstein D, Zheng M, Liao G, Allard J, Klumpp K, Webster R, Peltz G, Webby RJ. H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load. MBio. 2011 Sep 6;2(5). pii: e00171-1doi: 10.1128/mBio.00171-1Print 2011.   PubMed 21896679     FullText

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Participants Adrianus CM Boon       Washington University School of Medicine,  St. Louis, MO
Richard J Webby       St. Jude Children's Research Hospital,  Memphis, TN
With: Finkelstein D, Zheng M, Liao G, Allard J, Klumpp K, Webster R, Peltz G
ContactAdrianus CM Boon     Lab web site
AcknowledgementsFunding provided by the National Institute of Allergy and Infectious Diseases, U.S. Department of Health and Human Services (contract no. HHSN266200700005C); American Lebanese Syrian Associated Charities (ALSAC)
Project type Phenotype strain survey data set
MPD identifiersBoon1     MPD:469
Data changelog No updates/corrections.       Initial release date: 04/2013.
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Summary of procedures that were conducted
• body weight Influenza A (H5N1) virus (several doses) vs. baseline.
• health assessment Survival rate, influenza A (H5N1) virus (several doses). Strain H5N1 susceptibility score.
Mice: inbred   23 strains   ♀   age 6-9wks   3 experimental groups