MPD: Project measures / variables set: Rusyn5 liver

Project measures / variables set: Rusyn5 liver_GSHratio

ID, description, units	MPD:43029 liver_GSHratio ratio of reduced to oxidized liver glutathione [ratio] high-fat diet and ethanol study
Measures	• high-fat only • high-fat and ethanol
Data set, strains	Rusyn5 inbred 14 strains sex: m age: 8-14wks
Procedure	metabolite quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0000609 liver physiology trait VT:0010489 response to alcohol trait VT:0010516 blood glutathione amount MA:0000358 liver MP:0011601 abnormal glutathione peroxidase activity

Values Means Δ Means Z-scores

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Rusyn5 - ratio of reduced to oxidized liver glutathione

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	4921.3242	4921.3242	85.7044	< 0.0001
strain	13	5151.6408	396.2801	6.9012	< 0.0001
group:strain	13	1295.6256	99.6635	1.7356	0.079
Residuals	55	3158.215	57.4221

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn5	43029	metabolite quantification	high-fat diet and ethanol	ratio of reduced to oxidized liver glutathione [ratio] high-fat only liver_GSHratio_hf	inbred	14	m	8-14wks
Rusyn5	43030	metabolite quantification	high-fat diet and ethanol	ratio of reduced to oxidized liver glutathione [ratio] high-fat and ethanol liver_GSHratio_hfe	inbred	14	m	8-14wks