Project measure / variable:   Gould1   blood_lithium300

ID, description, units MPD:37406   blood_lithium300   serum lithium concentration   [mmol/L]  dose 300 mg/kg  
lithium study
Data set, strains Gould1   inbred   11 strains     sex: m     age: 7-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Gould1 - serum lithium concentration dose 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested11 strains
Mean of the strain means1.29   mmol/L
Median of the strain means1.24   mmol/L
SD of the strain means± 0.244
Coefficient of variation (CV)0.189
Min–max range of strain means0.940   –   1.63   mmol/L
Mean sample size per strain7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 10 4.2513 0.4251 9.665 < 0.0001
Residuals 72 3.167 0.044


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 1.57 0.205   8 0.0724 0.13 1.35, 1.86 1.16
A/J m 1.49 0.0875   8 0.0309 0.0586 1.38, 1.62 0.84
BALB/cJ m 1.63 0.304   8 0.107 0.187 1.14, 2.22 1.41
C3H/HeNHsd m 1.4 0.236   8 0.0833 0.168 1.2, 1.8 0.47
C57BL/6J m 1.09 0.14   7 0.0531 0.129 0.93, 1.32 -0.81
CBA/J m 1.19 0.207   8 0.0732 0.174 0.75, 1.44 -0.4
Crl:CD-1(ICR) m 0.97 0.269   6 0.11 0.277 0.6, 1.26 -1.3
DBA/2J m 1.24 0.106   8 0.0375 0.0857 1.11, 1.38 -0.19
FVB/NJ m 0.94 0.113   6 0.0462 0.12 0.78, 1.06 -1.42
Hsd:NIHS m 1.13 0.229   8 0.0809 0.202 0.9, 1.56 -0.64
NTac:NIHBS m 1.5 0.266   8 0.0941 0.177 1.17, 2.04 0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 1.575 0.0742 1.7228 1.4272
A/J m 1.4925 0.0742 1.6403 1.3447
BALB/cJ m 1.6275 0.0742 1.7753 1.4797
C3H/HeNHsd m 1.3988 0.0742 1.5466 1.2509
C57BL/6J m 1.0886 0.0793 1.2466 0.9305
CBA/J m 1.1925 0.0742 1.3403 1.0447
Crl:CD-1(ICR) m 0.97 0.0856 1.1407 0.7993
DBA/2J m 1.2375 0.0742 1.3853 1.0897
FVB/NJ m 0.94 0.0856 1.1107 0.7693
Hsd:NIHS m 1.1325 0.0742 1.2803 0.9847
NTac:NIHBS m 1.5012 0.0742 1.6491 1.3534




  GWAS USING LINEAR MIXED MODELS