MPD: Project measures / variables set: Rhodes1 DG

Project measures / variables set: Rhodes1 DG_density

ID, description, units	MPD:34607 DG_density hippocampus: density of new neurons in dentate gyrus [n/mm³] exercise study
Measures	• control • with running wheel
Data set, strains	Rhodes1 inbred 12 strains sex: both age: 15wks
Procedure	microscopy
Comparison	control group vs. treated group
Ontology mappings	VT:0000812 dentate gyrus morphology trait VT:0006008 neurogenesis trait VT:0015026 neuron quantity VT:1000152 wellness/fitness trait MA:0000946 dentate gyrus granule cell layer MP:0000812 abnormal dentate gyrus morphology MP:0012735 abnormal response to exercise

Values Means Δ Means Z-scores

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Rhodes1 - hippocampus: density of new neurons in dentate gyrus

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	3028.8009	3028.8009	349.6941	< 0.0001
group:sex	1	0.3373	0.3373	0.0389	0.8438
group:sex:strain	11	107.9431	9.813	1.133	0.34
group:strain	11	312.7977	28.4362	3.2831	0.0005
Residuals	144	1247.2253	8.6613
sex	1	5.0172	5.0172	0.5793	0.4478
sex:strain	11	123.5941	11.2358	1.2972	0.2316
strain	11	492.904	44.8095	5.1735	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rhodes1	34607	microscopy	exercise	hippocampus: density of new neurons in dentate gyrus [n/mm³] control DG_density_control	inbred	12	both	15wks
Rhodes1	34608	microscopy	exercise	hippocampus: density of new neurons in dentate gyrus [n/mm³] with running wheel DG_density_wheel	inbred	12	both	15wks