Project measure / variable:   Rhodes1   DG_density_wheel

ID, description, units MPD:34608   DG_density_wheel   hippocampus: density of new neurons in dentate gyrus   [n/mm3]  with running wheel  
exercise study
Data set, strains Rhodes1   inbred   12 strains     sex: both     age: 15wks
Procedure microscopy
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rhodes1 - hippocampus: density of new neurons in dentate gyrus with running wheel



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means11.6   n/mm3 11.1   n/mm3
Median of the strain means12.1   n/mm3 11.5   n/mm3
SD of the strain means± 3.39 ± 2.94
Coefficient of variation (CV)0.293 0.263
Min–max range of strain means5.98   –   16.5   n/mm3 5.38   –   16.4   n/mm3
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.1422 4.1422 0.2632 0.6095
strain 11 664.1603 60.3782 3.8365 0.0002
sex:strain 11 221.5244 20.1386 1.2796 0.2537
Residuals 72 1133.1177 15.7377


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.66 5.16   4 2.58 0.775 1.48, 13.7 -1.45
129S1/SvImJ m 5.38 3.1   4 1.55 0.576 2.6, 9.74 -1.97
AKR/J f 16.5 4.12   4 2.06 0.249 10.5, 19.5 1.45
AKR/J m 13.1 5.76   4 2.88 0.44 6.1, 19.2 0.66
B6129SF1/J f 13.1 6.13   4 3.07 0.47 6.5, 21.3 0.45
B6129SF1/J m 16.4 6.64   4 3.32 0.404 8.87, 24.4 1.79
B6D2F1/J f 13.0 4.22   4 2.11 0.325 8.01, 17.7 0.42
B6D2F1/J m 12.2 4.67   4 2.34 0.384 6.8, 17.4 0.36
BALB/cByJ f 15.5 4.71   4 2.35 0.304 9.9, 21.2 1.16
BALB/cByJ m 10.8 2.4   4 1.2 0.222 8.33, 13.9 -0.12
BTBR T+ Itpr3tf/J f 11.6 1.94   5 0.868 0.167 9.17, 14.0 0.01
BTBR T+ Itpr3tf/J m 10.7 2.69   3 1.55 0.251 7.8, 13.1 -0.15
C57BL/10J f 14.9 4.32   4 2.16 0.29 11.5, 20.9 0.98
C57BL/10J m 9.88 3.8   4 1.9 0.385 5.78, 14.6 -0.43
C57BL/6J f 10.9 3.56   4 1.78 0.327 6.63, 15.1 -0.2
C57BL/6J m 9.41 2.7   4 1.35 0.286 5.79, 12.3 -0.59
CAST/EiJ f 10.2 2.26   4 1.13 0.222 7.4, 12.9 -0.41
CAST/EiJ m 13.0 3.0   4 1.5 0.231 8.6, 15.3 0.63
DBA/2J f 5.98 1.6   4 0.8 0.267 3.73, 7.41 -1.65
DBA/2J m 7.32 1.66   4 0.832 0.227 4.98, 8.92 -1.3
NOD/ShiLtJ f 12.6 0.806   4 0.403 0.0637 12.0, 13.8 0.3
NOD/ShiLtJ m 12.3 6.13   4 3.07 0.499 8.42, 21.3 0.39
SM/J f 8.03 3.79   4 1.89 0.472 5.87, 13.7 -1.05
SM/J m 13.3 2.65   4 1.33 0.199 9.91, 16.0 0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.6625 1.9835 10.6166 2.7084
129S1/SvImJ m 5.3825 1.9835 9.3366 1.4284
AKR/J f 16.525 1.9835 20.4791 12.5709
AKR/J m 13.1 1.9835 17.0541 9.1459
B6129SF1/J f 13.05 1.9835 17.0041 9.0959
B6129SF1/J m 16.4175 1.9835 20.3716 12.4634
B6D2F1/J f 12.9775 1.9835 16.9316 9.0234
B6D2F1/J m 12.175 1.9835 16.1291 8.2209
BALB/cByJ f 15.5 1.9835 19.4541 11.5459
BALB/cByJ m 10.8325 1.9835 14.7866 6.8784
BTBR T+ Itpr3tf/J f 11.614 1.7741 15.1507 8.0773
BTBR T+ Itpr3tf/J m 10.7 2.2904 15.2658 6.1342
C57BL/10J f 14.875 1.9835 18.8291 10.9209
C57BL/10J m 9.8825 1.9835 13.8366 5.9284
C57BL/6J f 10.875 1.9835 14.8291 6.9209
C57BL/6J m 9.415 1.9835 13.3691 5.4609
CAST/EiJ f 10.2125 1.9835 14.1666 6.2584
CAST/EiJ m 13.025 1.9835 16.9791 9.0709
DBA/2J f 5.9825 1.9835 9.9366 2.0284
DBA/2J m 7.315 1.9835 11.2691 3.3609
NOD/ShiLtJ f 12.65 1.9835 16.6041 8.6959
NOD/ShiLtJ m 12.285 1.9835 16.2391 8.3309
SM/J f 8.0275 1.9835 11.9816 4.0734
SM/J m 13.3275 1.9835 17.2816 9.3734


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.0225 1.4026 8.8185 3.2265
AKR/J both 14.8125 1.4026 17.6085 12.0165
B6129SF1/J both 14.7337 1.4026 17.5297 11.9378
B6D2F1/J both 12.5763 1.4026 15.3722 9.7803
BALB/cByJ both 13.1662 1.4026 15.9622 10.3703
BTBR T+ Itpr3tf/J both 11.157 1.4486 14.0447 8.2693
C57BL/10J both 12.3787 1.4026 15.1747 9.5828
C57BL/6J both 10.145 1.4026 12.941 7.349
CAST/EiJ both 11.6187 1.4026 14.4147 8.8228
DBA/2J both 6.6488 1.4026 9.4447 3.8528
NOD/ShiLtJ both 12.4675 1.4026 15.2635 9.6715
SM/J both 10.6775 1.4026 13.4735 7.8815




  GWAS USING LINEAR MIXED MODELS