MPD: Project measures / variables set: Korstanje1 ACR

Project measures / variables set: Korstanje1 ACR

ID, description, units	MPD:29721 ACR albumin-creatinine ratio (urine ACR) [mg/g]
Measures	• 12mo • 18mo • 24mo
Data set, strains	Korstanje1 inbred 30 strains sex: both
Procedure	urinalysis
Comparison	timecourse, same cohort (aging study)
Ontology mappings	VT:0001757 urine molecular composition trait VT:0002136 kidney physiology trait VT:0002847 glomerular filtration trait MA:0002545 urine MP:0006315 abnormal urine protein level MP:0011469 abnormal urine creatinine level MP:0020153 abnormal urine albumin level

SIDE-BY-SIDE STRAIN CURVES

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	22867.3949	22867.3949	0.3868	0.5365
between strain	8	1156847.6795	144605.9599	2.4458	0.0238
between sex:strain	8	899802.4023	112475.3003	1.9023	0.0773
between Residuals	57	3370095.2167	59124.4775
within age	2	1341646.64	670823.32	16.406	< 0.0001
within age:sex	2	14402.7973	7201.3987	0.1761	0.8387
within age:strain	16	935439.8477	58464.9905	1.4299	0.1402
within age:sex:strain	16	510286.4816	31892.9051	0.78	0.705
within Residuals	114	4661326.9	40888.8325

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

	Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
	Korstanje1	29721	urinalysis	(none)	albumin-creatinine ratio (urine ACR) [mg/g] at age 12mo ACR_M12	inbred	30	both	52wks
	Korstanje1	29722	urinalysis	(none)	albumin-creatinine ratio (urine ACR) [mg/g] at age 18mo ACR_M18	inbred	30	both	78wks
	Korstanje1	29723	urinalysis	(none)	albumin-creatinine ratio (urine ACR) [mg/g] at age 24mo ACR_M24	inbred	25	both	104wks