Phenotype measure:   Korstanje1   ACR_M18


  STRAIN COMPARISON PLOT
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Korstanje1 - albumin-creatinine ratio (urine ACR) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains29 strains
Mean of the strain means158   mg/g 83.2   mg/g
Median of the strain means43.0   mg/g 29.9   mg/g
SD of the strain means± 243 ± 137
Coefficient of variation (CV)1.54 1.65
Min–max range of strain means0   –   974   mg/g 0   –   600   mg/g
Mean sample size per strain7.4   mice 7.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 774179.1052 774179.1052 6.7286 0.0099
strain 28 10448615.3959 373164.8356 3.2433 < 0.0001
sex:strain 28 6258418.8401 223514.9586 1.9426 0.0034
Residuals 363 41766107.3381 115058.1469


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 48.2 60.7   6 24.8 1.26 -0.45
129S1/SvImJ m 31.4 34.3   8 12.1 1.09 -0.38
A/J f 200.0 186.0   6 76.0 0.93 43.0, 442.0 0.18
A/J m 197.0 151.0   7 57.0 0.765 0.83
BALB/cByJ f 0.0 0.0   8 0.0 0.0 -0.65
BALB/cByJ m 0.0 0.0   6 0.0 0.0 -0.61
BTBR T+ Itpr3tf/J f 73.7 75.7   6 30.9 1.03 -0.35
BTBR T+ Itpr3tf/J m 1.71 4.54   7 1.71 2.65 -0.6
BUB/BnJ f 461.0 691.0   12 199.0 1.5 1.25
BUB/BnJ m 16.5 36.6   6 15.0 2.22 -0.49
C3H/HeJ f 26.0 29.5   6 12.0 1.14 -0.54
C3H/HeJ m 1.17 2.86   6 1.17 2.45 -0.6
C57BL/10J f 19.8 21.7   6 8.85 1.09 -0.57
C57BL/10J m 35.4 47.3   8 16.7 1.34 -0.35
C57BL/6J f 143.0 213.0   7 80.5 1.49 -0.06
C57BL/6J m 59.6 139.0   8 49.1 2.33 -0.17
C57BLKS/J f 16.2 44.7   12 12.9 2.75 -0.58
C57BLKS/J m 23.4 32.6   8 11.5 1.4 -0.44
C57BR/cdJ f 13.9 31.7   7 12.0 2.29 -0.59
C57BR/cdJ m 0.0 0.0   7 0.0 0.0 -0.61
C57L/J f 0.0 0.0   8 0.0 0.0 -0.65
C57L/J m 20.5 23.5   6 9.58 1.14 -0.46
CAST/EiJ f 43.2 72.6   5 32.5 1.68 -0.47
CBA/J f 0.0 0.0   8 0.0 0.0 -0.65
CBA/J m 34.5 29.0   6 11.9 0.842 -0.36
DBA/2J f 23.0 60.9   7 23.0 2.65 -0.55
DBA/2J m 23.5 37.7   10 11.9 1.6 -0.44
FVB/NJ f 60.4 154.0   7 58.3 2.55 -0.4
FVB/NJ m 23.3 39.7   6 16.2 1.7 -0.44
KK/HlJ f 974.0 904.0   8 320.0 0.929 3.36
KK/HlJ m 425.0 644.0   7 243.0 1.52 18.0, 1840.0 2.5
LP/J f 7.83 13.5   6 5.53 1.73 -0.62
LP/J m 65.2 98.4   8 34.8 1.51 -0.13
MRL/MpJ f 791.0 1160.0   7 438.0 1.47 2.61
MRL/MpJ m 0.0 0.0   6 0.0 0.0 -0.61
NOD.B10Sn-H2b/J f 39.8 88.3   10 27.9 2.22 -0.48
NOD.B10Sn-H2b/J m 173.0 221.0   6 90.4 1.28 0.66
NON/ShiLtJ f 592.0 1312.0   8 464.0 2.22 1.79
NON/ShiLtJ m 29.9 18.5   8 6.54 0.619 -0.39
NZO/HlLtJ f 259.0 434.0   7 164.0 1.67 27.0, 1230.0 0.42
NZO/HlLtJ m 162.0 183.0   7 69.3 1.13 0.58
NZW/LacJ f 220.0 515.0   6 210.0 2.34 0.26
NZW/LacJ m 36.8 62.1   8 21.9 1.69 -0.34
P/J f 38.3 73.0   6 29.8 1.91 -0.49
P/J m 46.8 79.5   8 28.1 1.7 -0.27
PL/J f 1.67 4.08   6 1.67 2.45 -0.64
PL/J m 2.5 6.12   6 2.5 2.45 -0.59
PWD/PhJ f 23.6 42.6   7 16.1 1.81 -0.55
PWD/PhJ m 600.0 661.0   6 270.0 1.1 3.77
RIIIS/J f 11.7 28.4   7 10.7 2.43 -0.6
RIIIS/J m 25.8 31.1   8 11.0 1.21 -0.42
SJL/J f 228.0 357.0   7 135.0 1.56 0.29
SJL/J m 1.0 2.0   4 1.0 2.0 -0.6
SM/J f 166.0 240.0   8 85.0 1.45 0.03
SM/J m 214.0 181.0   8 64.0 0.846 26.0, 503.0 0.96
SWR/J f 201.0 228.0   7 86.0 1.13 19.0, 648.0 0.18
SWR/J m 3.0 7.94   7 3.0 2.65 -0.59
WSB/EiJ f 42.8 74.0   12 21.4 1.73 -0.47
WSB/EiJ m 160.0 78.8   7 29.8 0.493 58.0, 291.0 0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 48.1667 138.4787 320.4879 -224.1546
129S1/SvImJ m 31.375 119.9261 267.2121 -204.4621
A/J f 200.3333 138.4787 472.6546 -71.9879
A/J m 197.1429 128.2064 449.2634 -54.9777
BALB/cByJ f 0.0 119.9261 235.8371 -235.8371
BALB/cByJ m 0.0 138.4787 272.3213 -272.3213
BTBR T+ Itpr3tf/J f 73.6667 138.4787 345.9879 -198.6546
BTBR T+ Itpr3tf/J m 1.7143 128.2064 253.8348 -250.4062
BUB/BnJ f 461.0833 97.9192 653.6436 268.5231
BUB/BnJ m 16.5 138.4787 288.8213 -255.8213
C3H/HeJ f 26.0 138.4787 298.3213 -246.3213
C3H/HeJ m 1.1667 138.4787 273.4879 -271.1546
C57BL/10J f 19.8333 138.4787 292.1546 -252.4879
C57BL/10J m 35.375 119.9261 271.2121 -200.4621
C57BL/6J f 142.8571 128.2064 394.9777 -109.2634
C57BL/6J m 59.625 119.9261 295.4621 -176.2121
C57BLKS/J f 16.25 97.9192 208.8102 -176.3102
C57BLKS/J m 23.375 119.9261 259.2121 -212.4621
C57BR/cdJ f 13.8571 128.2064 265.9777 -238.2634
C57BR/cdJ m 0.0 128.2064 252.1205 -252.1205
C57L/J f 0.0 119.9261 235.8371 -235.8371
C57L/J m 20.5 138.4787 292.8213 -251.8213
CBA/J f 0.0 119.9261 235.8371 -235.8371
CBA/J m 34.5 138.4787 306.8213 -237.8213
DBA/2J f 23.0 128.2064 275.1205 -229.1205
DBA/2J m 23.5 107.2652 234.4392 -187.4392
FVB/NJ f 60.4286 128.2064 312.5491 -191.6919
FVB/NJ m 23.3333 138.4787 295.6546 -248.9879
KK/HlJ f 973.5 119.9261 1209.3371 737.6629
KK/HlJ m 424.8571 128.2064 676.9777 172.7366
LP/J f 7.8333 138.4787 280.1546 -264.4879
LP/J m 65.25 119.9261 301.0871 -170.5871
MRL/MpJ f 790.7143 128.2064 1042.8348 538.5938
MRL/MpJ m 0.0 138.4787 272.3213 -272.3213
NOD.B10Sn-H2b/J f 39.8 107.2652 250.7392 -171.1392
NOD.B10Sn-H2b/J m 173.0 138.4787 445.3213 -99.3213
NON/ShiLtJ f 592.125 119.9261 827.9621 356.2879
NON/ShiLtJ m 29.875 119.9261 265.7121 -205.9621
NZO/HlLtJ f 259.2857 128.2064 511.4062 7.1652
NZO/HlLtJ m 161.8571 128.2064 413.9777 -90.2634
NZW/LacJ f 219.8333 138.4787 492.1546 -52.4879
NZW/LacJ m 36.75 119.9261 272.5871 -199.0871
P/J f 38.3333 138.4787 310.6546 -233.9879
P/J m 46.75 119.9261 282.5871 -189.0871
PL/J f 1.6667 138.4787 273.9879 -270.6546
PL/J m 2.5 138.4787 274.8213 -269.8213
PWD/PhJ f 23.5714 128.2064 275.6919 -228.5491
PWD/PhJ m 600.0 138.4787 872.3213 327.6787
RIIIS/J f 11.7143 128.2064 263.8348 -240.4062
RIIIS/J m 25.75 119.9261 261.5871 -210.0871
SJL/J f 228.1429 128.2064 480.2634 -23.9777
SJL/J m 1.0 169.6011 334.5241 -332.5241
SM/J f 165.875 119.9261 401.7121 -69.9621
SM/J m 213.875 119.9261 449.7121 -21.9621
SWR/J f 201.2857 128.2064 453.4062 -50.8348
SWR/J m 3.0 128.2064 255.1205 -249.1205
WSB/EiJ f 42.8333 97.9192 235.3936 -149.7269
WSB/EiJ m 159.8571 128.2064 411.9777 -92.2634


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 39.7708 91.5951 219.8944 -140.3528
A/J both 198.7381 94.3573 384.2938 13.1824
BALB/cByJ both 0.0 91.5951 180.1236 -180.1236
BTBR T+ Itpr3tf/J both 37.6905 94.3573 223.2461 -147.8652
BUB/BnJ both 238.7917 84.8006 405.5537 72.0296
C3H/HeJ both 13.5833 97.9192 206.1436 -178.9769
C57BL/10J both 27.6042 91.5951 207.7278 -152.5194
C57BL/6J both 101.2411 87.7769 273.8562 -71.374
C57BLKS/J both 19.8125 77.412 172.0447 -132.4197
C57BR/cdJ both 6.9286 90.6556 185.2047 -171.3476
C57L/J both 10.25 91.5951 190.3736 -169.8736
CBA/J both 17.25 91.5951 197.3736 -162.8736
DBA/2J both 23.25 83.5803 187.6125 -141.1125
FVB/NJ both 41.881 94.3573 227.4366 -143.6747
KK/HlJ both 699.1786 87.7769 871.7937 526.5635
LP/J both 36.5417 91.5951 216.6653 -143.5819
MRL/MpJ both 395.3571 94.3573 580.9128 209.8015
NOD.B10Sn-H2b/J both 106.4 87.5816 278.6311 -65.8311
NON/ShiLtJ both 311.0 84.8006 477.762 144.238
NZO/HlLtJ both 210.5714 90.6556 388.8476 32.2953
NZW/LacJ both 128.2917 91.5951 308.4153 -51.8319
P/J both 42.5417 91.5951 222.6653 -137.5819
PL/J both 2.0833 97.9192 194.6436 -190.4769
PWD/PhJ both 311.7857 94.3573 497.3414 126.23
RIIIS/J both 18.7321 87.7769 191.3473 -153.883
SJL/J both 114.5714 106.3031 323.6187 -94.4759
SM/J both 189.875 84.8006 356.637 23.113
SWR/J both 102.1429 90.6556 280.419 -76.1333
WSB/EiJ both 101.3452 80.6614 259.9676 -57.2771




  GWAS USING LINEAR MIXED MODELS