Phenotype measures set:   Threadgill1   liver_necrosis

ID, description, units MPD:19404   liver_necrosis   necrosis   [%]
acetaminophen study
Measures • dose (mg/kg): control    • 100    • 200    • 300
Data set, strains Threadgill1   inbred w/CC7   37 strains     sex: m     age: 8-17wks
Procedure histopathology
Comparisoncontrol group vs. multiple treatment / dosage groups
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
Values
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  OVERLAPPING STRAIN CURVES
Data
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Threadgill1 - necrosis





  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
dose 3 39853.3613 13284.4538 38.0802 < 0.0001
strain 5 16390.5599 3278.112 9.3968 < 0.0001
dose:strain 15 21517.2393 1434.4826 4.112 < 0.0001
Residuals 58 20233.5833 348.8549

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDDrug or
challenge
Description and varname PanelStrains
tested
SexAge
Threadgill1 19404 histopathology acetaminophen necrosis   [%]   control   liver_necrosis_ctrl inbred w/CC7 37 m 8-17wks
Threadgill1 19405 histopathology acetaminophen necrosis   [%]   dose: 100 mg/kg   liver_necrosis_Rx100 inbred w/CC7 6 m 8-17wks
Threadgill1 19435 histopathology acetaminophen necrosis   [%]   dose: 200 mg/kg   liver_necrosis_Rx200 inbred w/CC7 7 m 8-17wks
Threadgill1 19465 histopathology acetaminophen necrosis   [%]   dose: 300 mg/kg   liver_necrosis_Rx300 inbred w/CC7 37 m 8-17wks