MPD: Project measures / variables set: Schoonjans1 keto_LCA

Project measures / variables set: Schoonjans1 keto_LCA_feces

ID, description, units	MPD:112758 keto_LCA_feces bile acid 7-ketolithocholic acid amount in feces, at 24 wks [ng/mL] high-fat diet study
Measures	• CD • HFD
Data set, strains	Schoonjans1 BXD w/par 36 strains sex: m age: 24wks
Procedure	biomarker quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0010919 feces bile acid amount MA:0002509 feces MP:0003868 abnormal feces composition

Values Means Δ Means Z-scores

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Schoonjans1 - bile acid 7-ketolithocholic acid amount in feces, at 24 wks

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	34.909	34.909	285.9324	< 0.0001
group:strain	35	15.4405	0.4412	3.6134	< 0.0001
Residuals	275	33.5743	0.1221
strain	35	47.4695	1.3563	11.1089	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Schoonjans1	112758	biomarker quantification	high-fat diet	bile acid 7-ketolithocholic acid amount in feces, at 24 wks [ng/mL] CD keto_LCA_feces_CD	BXD w/par	36	m	24wks
Schoonjans1	112759	biomarker quantification	high-fat diet	bile acid 7-ketolithocholic acid amount in feces, at 24 wks [ng/mL] HFD keto_LCA_feces_HFD	BXD w/par	36	m	24wks