MPD: Project measures / variables set: Schoonjans1 TCDCA_plasma

Project measures / variables set: Schoonjans1 TCDCA_plasma_t30

ID, description, units	MPD:112706 TCDCA_plasma_t30 plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min [ng/mL] high-fat diet study
Measures	• CD • HFD
Data set, strains	Schoonjans1 BXD w/par 36 strains sex: m age: 20wks
Procedure	biomarker quantification
Comparison	control group vs. treated group
Ontology mappings	VT:0010917 bile acid amount MA:0002501 plasma

Values Means Δ Means Z-scores

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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	8462.8581	8462.8581	34.9875	< 0.0001
group:strain	35	14879.035	425.1153	1.7575	0.0076
Residuals	251	60712.5272	241.8826
strain	35	36263.3918	1036.0969	4.2835	< 0.0001

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Schoonjans1	112706	biomarker quantification	high-fat diet	plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min [ng/mL] CD TCDCA_plasma_t30_CD	BXD w/par	36	m	20wks
Schoonjans1	112707	biomarker quantification	high-fat diet	plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min [ng/mL] HFD TCDCA_plasma_t30_HFD	BXD w/par	36	m	20wks