Project measure / variable:   Schoonjans1   TCDCA_plasma_t30_CD

ID, description, units MPD:112706   TCDCA_plasma_t30_CD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means20.159   ng/mL
Median of the strain means18.237   ng/mL
SD of the strain means± 10.636
Coefficient of variation (CV)0.5276
Min–max range of strain means2.548   –   50.69   ng/mL
Mean sample size per strain4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 18644.1815 532.6909 4.049 < 0.0001
Residuals 129 16971.4598 131.5617


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.3317 1.2031   5 0.53804 0.19 5.1625, 7.704 -1.3
BXD100 m 21.295 7.2805   5 3.256 0.3419 14.694, 33.752 0.11
BXD11 m 20.308 12.654   4 6.327 0.6231 7.642, 32.304 0.01
BXD12 m 35.157 8.3997   3 4.8496 0.2389 30.12, 44.854 1.41
BXD27 m 24.191 6.5621   4 3.2811 0.2713 16.858, 32.818 0.38
BXD32 m 16.588 7.9939   5 3.575 0.4819 8.728, 25.938 -0.34
BXD34 m 19.11 7.5162   5 3.3613 0.3933 9.522, 27.064 -0.1
BXD39 m 22.925 4.7752   3 2.757 0.2083 18.33, 27.862 0.26
BXD40 m 25.732 6.6763   4 3.3382 0.2595 19.27, 32.516 0.52
BXD43 m 6.631 5.4902   7 2.0751 0.828 0.856, 14.525 -1.27
BXD45 m 35.367 14.915   4 7.4575 0.4217 21.308, 54.24 1.43
BXD48 m 17.952 6.5465   5 2.9277 0.3647 10.436, 27.01 -0.21
BXD48a m 12.025 8.6842   4 4.3421 0.7222 5.76, 24.78 -0.76
BXD49 m 25.102 8.8662   5 3.9651 0.3532 12.036, 34.946 0.46
BXD51 m 22.618 10.655   5 4.7651 0.4711 9.354, 34.098 0.23
BXD53 m 14.054 6.1989   4 3.0995 0.4411 10.042, 23.272 -0.57
BXD55 m 17.057 7.0176   5 3.1383 0.4114 4.964, 22.554 -0.29
BXD6 m 13.187 7.1602   5 3.2021 0.543 4.626, 20.384 -0.66
BXD62 m 50.69 20.596   5 9.2108 0.4063 28.29, 77.86 2.87
BXD63 m 8.37 5.3783   4 2.6892 0.6426 4.078, 15.802 -1.11
BXD64 m 21.456 17.309   5 7.7408 0.8067 10.76, 50.83 0.12
BXD66 m 12.696 5.425   5 2.4261 0.4273 4.988, 18.882 -0.7
BXD67 m 2.548 1.4708   4 0.73538 0.5772 0.924, 4.178 -1.66
BXD69 m 15.334 5.5543   5 2.484 0.3622 8.964, 23.002 -0.45
BXD73 m 13.314 8.482   3 4.8971 0.6371 8.372, 23.108 -0.64
BXD75 m 33.344 17.408   5 7.7851 0.5221 16.004, 58.02 1.24
BXD77 m 17.022 6.9253   5 3.0971 0.4068 12.754, 29.338 -0.29
BXD79 m 35.075 28.041   5 12.541 0.7995 10.208, 81.73 1.4
BXD8 m 46.775 27.783   5 12.425 0.594 16.308, 84.79 2.5
BXD81 m 12.208 5.8781   3 3.3937 0.4815 6.01, 17.703 -0.75
BXD84 m 14.773 10.117   5 4.5246 0.6849 8.554, 32.54 -0.51
BXD87 m 16.212 8.0941   5 3.6198 0.4993 9.368, 29.582 -0.37
BXD89 m 19.238 6.757   5 3.0218 0.3512 12.724, 27.088 -0.09
BXD90 m 9.3012 4.6336   5 2.0722 0.4982 5.888, 16.818 -1.02
C57BL/6J m 23.226 7.0051   5 3.1328 0.3016 12.982, 32.41 0.29
DBA/2J m 18.522 14.077   4 7.0385 0.76 4.242, 37.904 -0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.3317 5.1295556192 16.4806514231 -3.8172514231
BXD100 m 21.2948 5.1295556192 31.4437514231 11.1458485769
BXD11 m 20.3075 5.7350175295 31.6543726412 8.9606273588
BXD12 m 35.1573333333 6.6222278289 48.259573281 22.0550933857
BXD27 m 24.1905 5.7350175295 35.5373726412 12.8436273588
BXD32 m 16.5876 5.1295556192 26.7365514231 6.4386485769
BXD34 m 19.1096 5.1295556192 29.2585514231 8.9606485769
BXD39 m 22.9246666667 6.6222278289 36.0269066143 9.822426719
BXD40 m 25.7315 5.7350175295 37.0783726412 14.3846273588
BXD43 m 6.631 4.3352657565 15.2084294762 -1.9464294762
BXD45 m 35.3665 5.7350175295 46.7133726412 24.0196273588
BXD48 m 17.9516 5.1295556192 28.1005514231 7.8026485769
BXD48a m 12.0245 5.7350175295 23.3713726412 0.6776273588
BXD49 m 25.1024 5.1295556192 35.2513514231 14.9534485769
BXD51 m 22.6184 5.1295556192 32.7673514231 12.4694485769
BXD53 m 14.054 5.7350175295 25.4008726412 2.7071273588
BXD55 m 17.0568 5.1295556192 27.2057514231 6.9078485769
BXD6 m 13.1868 5.1295556192 23.3357514231 3.0378485769
BXD62 m 50.6916 5.1295556192 60.8405514231 40.5426485769
BXD63 m 8.37 5.7350175295 19.7168726412 -2.9768726412
BXD64 m 21.4556 5.1295556192 31.6045514231 11.3066485769
BXD66 m 12.696 5.1295556192 22.8449514231 2.5470485769
BXD67 m 2.548 5.7350175295 13.8948726412 -8.7988726412
BXD69 m 15.334 5.1295556192 25.4829514231 5.1850485769
BXD73 m 13.314 6.6222278289 26.4162399477 0.2117600523
BXD75 m 33.344 5.1295556192 43.4929514231 23.1950485769
BXD77 m 17.022 5.1295556192 27.1709514231 6.8730485769
BXD79 m 35.0748 5.1295556192 45.2237514231 24.9258485769
BXD8 m 46.7748 5.1295556192 56.9237514231 36.6258485769
BXD81 m 12.2076666667 6.6222278289 25.3099066143 -0.894573281
BXD84 m 14.7726 5.1295556192 24.9215514231 4.6236485769
BXD87 m 16.2116 5.1295556192 26.3605514231 6.0626485769
BXD89 m 19.2376 5.1295556192 29.3865514231 9.0886485769
BXD90 m 9.3012 5.1295556192 19.4501514231 -0.8477514231
C57BL/6J m 23.2256 5.1295556192 33.3745514231 13.0766485769
DBA/2J m 18.522 5.7350175295 29.8688726412 7.1751273588




  GWAS USING LINEAR MIXED MODELS