Project measure / variable:   Schoonjans1   TCDCA_plasma_t30_HFD

ID, description, units MPD:112707   TCDCA_plasma_t30_HFD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, after 30 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means30.867   ng/mL
Median of the strain means28.618   ng/mL
SD of the strain means± 14.856
Coefficient of variation (CV)0.4813
Min–max range of strain means9.649   –   69.32   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 32498.2453 928.5213 2.5898 < 0.0001
Residuals 122 43741.0674 358.5333


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 10.478 5.6259   5 2.516 0.5369 5.802, 19.044 -1.37
BXD100 m 22.208 13.541   9 4.5136 0.6097 3.288, 48.42 -0.58
BXD11 m 27.213 9.2325   3 5.3304 0.3393 17.538, 35.928 -0.25
BXD12 m 37.195 28.49   4 14.245 0.766 9.26, 76.11 0.43
BXD27 m 55.86 26.386   5 11.8 0.4724 25.918, 97.02 1.68
BXD32 m 24.131 12.27   4 6.1348 0.5084 15.892, 42.35 -0.45
BXD34 m 34.376 18.503   4 9.2517 0.5383 15.952, 57.59 0.24
BXD39 m 31.701 23.686   3 13.675 0.7472 8.946, 56.22 0.06
BXD40 m 45.829 28.961   4 14.48 0.6319 27.454, 88.63 1.01
BXD43 m 12.159 2.1281   5 0.95174 0.175 10.238, 15.732 -1.26
BXD45 m 36.515 12.852   5 5.7477 0.352 18.226, 48.632 0.38
BXD48 m 22.2 7.6729   5 3.4314 0.3456 14.74, 33.856 -0.58
BXD48a m 63.31 16.458   4 8.229 0.26 45.076, 78.12 2.18
BXD49 m 18.665 3.133   5 1.4011 0.1679 14.776, 22.02 -0.82
BXD51 m 33.746 11.543   3 6.6643 0.3421 21.38, 44.236 0.19
BXD53 m 27.412 10.526   5 4.7074 0.384 17.39, 44.924 -0.23
BXD55 m 28.714 3.6603   5 1.637 0.1275 22.48, 31.764 -0.14
BXD6 m 23.13 17.023   5 7.6128 0.736 6.008, 49.753 -0.52
BXD62 m 41.097 9.9401   4 4.97 0.2419 27.408, 51.01 0.69
BXD63 m 17.222 3.3445   5 1.4957 0.1942 12.904, 21.09 -0.92
BXD64 m 33.719 12.486   5 5.5837 0.3703 15.916, 48.558 0.19
BXD66 m 18.017 6.1224   3 3.5348 0.3398 13.592, 25.004 -0.86
BXD67 m 9.649 4.2538   5 1.9024 0.4409 5.246, 16.708 -1.43
BXD69 m 69.32 45.907   4 22.954 0.6622 22.808, 121.5 2.59
BXD73 m 15.324 11.029   3 6.3677 0.7197 7.656, 27.964 -1.05
BXD75 m 46.595 15.304   4 7.6522 0.3285 32.368, 65.21 1.06
BXD77 m 28.522 5.6648   5 2.5334 0.1986 21.812, 36.562 -0.16
BXD79 m 40.898 45.769   5 20.469 1.1191 17.996, 122.7 0.68
BXD8 m 36.18 14.948   3 8.6304 0.4132 23.564, 52.69 0.36
BXD81 m 38.158 26.832   5 12.0 0.7032 14.502, 72.99 0.49
BXD84 m 20.618 25.634   5 11.464 1.2433 3.1, 65.46 -0.69
BXD87 m 14.165 5.9826   4 2.9913 0.4224 8.616, 22.564 -1.12
BXD89 m 38.462 27.388   5 12.248 0.7121 20.04, 86.82 0.51
BXD90 m 23.229 14.71   4 7.3551 0.6333 11.994, 44.036 -0.51
C57BL/6J m 54.45 24.469   3 14.127 0.4494 30.208, 79.14 1.59
DBA/2J m 10.743 8.774   3 5.0657 0.8167 5.2441, 20.862 -1.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 10.4782 8.4679789708 27.2414101417 -6.2850101417
BXD100 m 22.2082222222 6.3116588703 34.7027813549 9.7136630896
BXD11 m 27.2126666667 10.9321138434 48.8538779026 5.5714554307
BXD12 m 37.1955 9.4674883054 55.937338699 18.453661301
BXD27 m 55.8592 8.4679789708 72.6224101417 39.0959898583
BXD32 m 24.1315 9.4674883054 42.873338699 5.389661301
BXD34 m 34.3755 9.4674883054 53.117338699 15.633661301
BXD39 m 31.7006666667 10.9321138434 53.3418779026 10.0594554307
BXD40 m 45.8285 9.4674883054 64.570338699 27.086661301
BXD43 m 12.1592 8.4679789708 28.9224101417 -4.6040101417
BXD45 m 36.5152 8.4679789708 53.2784101417 19.7519898583
BXD48 m 22.2 8.4679789708 38.9632101417 5.4367898583
BXD48a m 63.309 9.4674883054 82.050838699 44.567161301
BXD49 m 18.6652 8.4679789708 35.4284101417 1.9019898583
BXD51 m 33.7463333333 10.9321138434 55.3875445693 12.1051220974
BXD53 m 27.4116 8.4679789708 44.1748101417 10.6483898583
BXD55 m 28.7136 8.4679789708 45.4768101417 11.9503898583
BXD6 m 23.13 8.4679789708 39.8932101417 6.3667898583
BXD62 m 41.097 9.4674883054 59.838838699 22.355161301
BXD63 m 17.2216 8.4679789708 33.9848101417 0.4583898583
BXD64 m 33.7192 8.4679789708 50.4824101417 16.9559898583
BXD66 m 18.0166666667 10.9321138434 39.6578779026 -3.6245445693
BXD67 m 9.649 8.4679789708 26.4122101417 -7.1142101417
BXD69 m 69.3225 9.4674883054 88.064338699 50.580661301
BXD73 m 15.324 10.9321138434 36.9652112359 -6.3172112359
BXD75 m 46.595 9.4674883054 65.336838699 27.853161301
BXD77 m 28.5216 8.4679789708 45.2848101417 11.7583898583
BXD79 m 40.8984 8.4679789708 57.6616101417 24.1351898583
BXD8 m 36.18 10.9321138434 57.8212112359 14.5387887641
BXD81 m 38.1576 8.4679789708 54.9208101417 21.3943898583
BXD84 m 20.618 8.4679789708 37.3812101417 3.8547898583
BXD87 m 14.1645 9.4674883054 32.906338699 -4.577338699
BXD89 m 38.4624 8.4679789708 55.2256101417 21.6991898583
BXD90 m 23.229 9.4674883054 41.970838699 4.487161301
C57BL/6J m 54.4526666667 10.9321138434 76.0938779026 32.8114554307
DBA/2J m 10.7433666667 10.9321138434 32.3845779026 -10.8978445693




  GWAS USING LINEAR MIXED MODELS