Project measure / variable:   Noll1   IgG2ac_d7

ID, description, units MPD:112612   IgG2ac_d7   immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection   [AUC]  day 7  
influenza A (H1N1) virus study
Data set, strains Noll1   CC RIX   39 strains     sex: f     age: 8-12 wks
Procedure immunoglobulin quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Noll1 - immunoglobulin G2a plus G2c (serum IgG2a pooled with IgG2c) area under curve (AUC) post-infection day 7



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested39 strains
Mean of the strain means0.52336   AUC
Median of the strain means0.33705   AUC
SD of the strain means± 0.52357
Coefficient of variation (CV)1.0004
Min–max range of strain means0.03486   –   2.0762   AUC
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 36 29.0994 0.8083 2.949 < 0.0001
Residuals 98 26.8614 0.2741


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
RIX:CC(002 x 021) f 0.69287 0.5771   4 0.28855 0.8329 0.14654, 1.2235 0.32
RIX:CC(003 x 051) f 0.05185 0.0   1   0.0 0.0 0.05185, 0.05185 -0.9
RIX:CC(003 x 062) f 0.19435 0.07515   3 0.04339 0.3867 0.11773, 0.26794 -0.63
RIX:CC(005 x 038) f 0.07191 0.03974   6 0.01622 0.5526 0.02252, 0.14276 -0.86
RIX:CC(007 x 075) f 2.0762 1.5465   2   1.0936 0.7449 0.98266, 3.1698 2.97
RIX:CC(013 x 041) f 0.28013 0.20005   6 0.08167 0.7142 0.10522, 0.58611 -0.46
RIX:CC(015 x 018) f 0.86202 0.69773   4 0.34887 0.8094 0.36569, 1.8807 0.65
RIX:CC(015 x 059) f 0.72688 0.42424   3 0.24493 0.5836 0.32801, 1.1726 0.39
RIX:CC(016 x 038) f 0.31035 0.15271   3 0.08817 0.4921 0.2097, 0.48607 -0.41
RIX:CC(017 x 041) f 0.49365 0.44958   3 0.25956 0.9107 0.19883, 1.0111 -0.06
RIX:CC(018 x 009) f 1.1513 1.2728   3 0.73482 1.1055 0.02624, 2.5327 1.2
RIX:CC(018 x 065) f 0.07233 0.06939   3 0.04006 0.9593 0.03171, 0.15245 -0.86
RIX:CC(019 x 002) f 0.33705 0.1828   6 0.07463 0.5424 0.11471, 0.6376 -0.36
RIX:CC(025 x 028) f 0.32881 0.35798   3 0.20668 1.0887 0.05314, 0.73339 -0.37
RIX:CC(026 x 034) f 0.66284 0.2297   2   0.16242 0.3465 0.50042, 0.82526 0.27
RIX:CC(028 x 030) f 0.69405 0.46798   3 0.27019 0.6743 0.18062, 1.0967 0.33
RIX:CC(032 x 013) f 0.20952 0.10497   4 0.05249 0.501 0.15122, 0.36686 -0.6
RIX:CC(032 x 017) f 1.1772 0.96925   5 0.43346 0.8234 0.4124, 2.7434 1.25
RIX:CC(035 x 020) f 0.09891 0.03565   4 0.01782 0.3604 0.04784, 0.13085 -0.81
RIX:CC(035 x 071) f 0.30843 0.116   2   0.08202 0.3761 0.2264, 0.39045 -0.41
RIX:CC(037 x 046) f 0.03486 0.02748   3 0.01586 0.7883 0.01682, 0.06648 -0.93
RIX:CC(037 x 057) f 0.41081 0.42317   4 0.21158 1.0301 0.09466, 1.0123 -0.21
RIX:CC(038 x 013) f 0.21113 0.15818   3 0.09133 0.7492 0.09325, 0.3909 -0.6
RIX:CC(041 x 016) f 0.22221 0.17343   5 0.07756 0.7805 0.08516, 0.5064 -0.58
RIX:CC(042 x 017) f 1.518 0.52056   3 0.30055 0.3429 1.169, 2.1163 1.9
RIX:CC(042 x 019) f 0.52641 0.44916   3 0.25933 0.8533 0.13826, 1.0184 0.01
RIX:CC(042 x 025) f 1.4811 1.484   4 0.74199 1.002 0.34168, 3.5914 1.83
RIX:CC(043 x 037) f 0.60646 0.53259   9 0.17753 0.8782 0.11849, 1.6276 0.16
RIX:CC(051 x 005) f 0.35264 0.3486   4 0.1743 0.9885 0.01406, 0.77153 -0.33
RIX:CC(051 x 009) f 0.80955 0.46086   3 0.26608 0.5693 0.52564, 1.3413 0.55
RIX:CC(052 x 007) f 1.9836 1.2376   2   0.8751 0.6239 1.1085, 2.8587 2.79
RIX:CC(057 x 052) f 0.38168 0.16537   3 0.09548 0.4333 0.24773, 0.56651 -0.27
RIX:CC(058 x 022) f 0.05361 0.01603   5 0.00716771 0.2989 0.03233, 0.07695 -0.9
RIX:CC(059 x 065) f 0.06303 0.0   1   0.0 0.0 0.06303, 0.06303 -0.88
RIX:CC(062 x 046) f 0.44428 0.0205   3 0.01183 0.0461 0.42817, 0.46735 -0.15
RIX:CC(063 x 002) f 0.04483 0.01562   3 0.00901896 0.3484 0.0272, 0.05694 -0.91
RIX:CC(074 x 058) f 0.21986 0.21687   3 0.12521 0.9864 0.06891, 0.46838 -0.58
RIX:CC(074 x 062) f 0.20353 0.05278   3 0.03047 0.2593 0.16562, 0.26381 -0.61
RIX:CC(075 x 035) f 0.04276 0.00909846   3 0.005253 0.2128 0.03226, 0.04822 -0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
RIX:CC(002 x 021) f 0.6928675 0.2617709688 1.2123434681 0.1733915319
RIX:CC(003 x 062) f 0.1943466667 0.3022670786 0.7941858468 -0.4054925134
RIX:CC(005 x 038) f 0.0719116667 0.213735101 0.4960620185 -0.3522386852
RIX:CC(007 x 075) f 2.07623 0.3702000543 2.8108799595 1.3415800405
RIX:CC(013 x 041) f 0.2801283333 0.213735101 0.7042786852 -0.1440220185
RIX:CC(015 x 018) f 0.8620225 0.2617709688 1.3814984681 0.3425465319
RIX:CC(015 x 059) f 0.7268833333 0.3022670786 1.3267225134 0.1270441532
RIX:CC(016 x 038) f 0.31035 0.3022670786 0.9101891801 -0.2894891801
RIX:CC(017 x 041) f 0.49365 0.3022670786 1.0934891801 -0.1061891801
RIX:CC(018 x 009) f 1.1512566667 0.3022670786 1.7510958468 0.5514174866
RIX:CC(018 x 065) f 0.07233 0.3022670786 0.6721691801 -0.5275091801
RIX:CC(019 x 002) f 0.3370483333 0.213735101 0.7611986852 -0.0871020185
RIX:CC(025 x 028) f 0.3288133333 0.3022670786 0.9286525134 -0.2710258468
RIX:CC(026 x 034) f 0.66284 0.3702000543 1.3974899595 -0.0718099595
RIX:CC(028 x 030) f 0.6940466667 0.3022670786 1.2938858468 0.0942074866
RIX:CC(032 x 013) f 0.2095225 0.2617709688 0.7289984681 -0.3099534681
RIX:CC(032 x 017) f 1.177204 0.2341350723 1.641837431 0.712570569
RIX:CC(035 x 020) f 0.0989125 0.2617709688 0.6183884681 -0.4205634681
RIX:CC(035 x 071) f 0.308425 0.3702000543 1.0430749595 -0.4262249595
RIX:CC(037 x 046) f 0.0348566667 0.3022670786 0.6346958468 -0.5649825134
RIX:CC(037 x 057) f 0.4108075 0.2617709688 0.9302834681 -0.1086684681
RIX:CC(038 x 013) f 0.21113 0.3022670786 0.8109691801 -0.3887091801
RIX:CC(041 x 016) f 0.222214 0.2341350723 0.686847431 -0.242419431
RIX:CC(042 x 017) f 1.5179666667 0.3022670786 2.1178058468 0.9181274866
RIX:CC(042 x 019) f 0.52641 0.3022670786 1.1262491801 -0.0734291801
RIX:CC(042 x 025) f 1.48107 0.2617709688 2.0005459681 0.9615940319
RIX:CC(043 x 037) f 0.6064622222 0.1745139792 0.9527795343 0.2601449101
RIX:CC(051 x 005) f 0.3526425 0.2617709688 0.8721184681 -0.1668334681
RIX:CC(051 x 009) f 0.80955 0.3022670786 1.4093891801 0.2097108199
RIX:CC(052 x 007) f 1.9836 0.3702000543 2.7182499595 1.2489500405
RIX:CC(057 x 052) f 0.38168 0.3022670786 0.9815191801 -0.2181591801
RIX:CC(058 x 022) f 0.053614 0.2341350723 0.518247431 -0.411019431
RIX:CC(062 x 046) f 0.44428 0.3022670786 1.0441191801 -0.1555591801
RIX:CC(063 x 002) f 0.0448333333 0.3022670786 0.6446725134 -0.5550058468
RIX:CC(074 x 058) f 0.21986 0.3022670786 0.8196991801 -0.3799791801
RIX:CC(074 x 062) f 0.2035266667 0.3022670786 0.8033658468 -0.3963125134
RIX:CC(075 x 035) f 0.0427633333 0.3022670786 0.6426025134 -0.5570758468




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA