Phenotype measure:   Kliethermes1   activity_HD


  STRAIN COMPARISON PLOT
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Kliethermes1 - activity (beam breaks) in head dip task to assess novelty seeking, 10 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means2975   n 2741   n
Median of the strain means2732   n 2554   n
SD of the strain means± 1393 ± 1051
Coefficient of variation (CV)0.468 0.383
Min–max range of strain means759   –   5184   n 1310   –   4507   n
Mean sample size per strain6.3   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2864401.7419 2864401.7419 8.4179 0.0042
strain 13 229417285.9619 17647483.5355 51.8627 < 0.0001
sex:strain 13 15333605.694 1179508.1303 3.4664 0.0001
Residuals 158 53763180.0 340273.2911


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1642.0 814.0   6 332.0 0.495 508.0, 2628.0 -0.96
129S1/SvImJ m 2301.0 637.0   6 260.0 0.277 1572.0, 3134.0 -0.42
A/J f 759.0 189.0   6 77.0 0.248 536.0, 988.0 -1.59
A/J m 1310.0 262.0   6 107.0 0.2 1024.0, 1690.0 -1.36
AKR/J f 2936.0 480.0   6 196.0 0.164 2404.0, 3648.0 -0.03
AKR/J m 3115.0 440.0   5 197.0 0.141 2438.0, 3608.0 0.36
BALB/cByJ f 3025.0 609.0   5 272.0 0.201 2132.0, 3746.0 0.04
BALB/cByJ m 1610.0 844.0   6 345.0 0.525 574.0, 2838.0 -1.08
BTBR T+ Itpr3tf/J f 2529.0 460.0   6 188.0 0.182 1972.0, 3254.0 -0.32
BTBR T+ Itpr3tf/J m 2808.0 548.0   6 224.0 0.195 2092.0, 3610.0 0.06
C3H/HeJ f 2470.0 546.0   6 223.0 0.221 1488.0, 3124.0 -0.36
C3H/HeJ m 1969.0 236.0   6 96.3 0.12 1720.0, 2386.0 -0.73
C57BL/6J f 3997.0 599.0   12 173.0 0.15 2882.0, 5268.0 0.73
C57BL/6J m 3382.0 615.0   12 178.0 0.182 2454.0, 4568.0 0.61
C57L/J f 5010.0 244.0   6 99.5 0.0487 4694.0, 5362.0 1.46
C57L/J m 4507.0 721.0   6 295.0 0.16 3212.0, 5110.0 1.68
DBA/2J f 2074.0 379.0   12 109.0 0.183 1576.0, 2772.0 -0.65
DBA/2J m 2185.0 389.0   12 112.0 0.178 1520.0, 2764.0 -0.53
FVB/NJ f 5184.0 691.0   5 309.0 0.133 4550.0, 6014.0 1.59
FVB/NJ m 4033.0 307.0   5 137.0 0.0761 3830.0, 4568.0 1.23
NOD/ShiLtJ f 5084.0 1434.0   6 585.0 0.282 2606.0, 6716.0 1.51
NOD/ShiLtJ m 4250.0 206.0   6 84.1 0.0485 4076.0, 4648.0 1.44
NZB/BlNJ f 1715.0 740.0   6 302.0 0.431 620.0, 2622.0 -0.9
NZB/BlNJ m 1912.0 279.0   6 114.0 0.146 1602.0, 2308.0 -0.79
PERA/EiJ f 1944.0 282.0   5 126.0 0.145 1514.0, 2202.0 -0.74
PERA/EiJ m 1628.0 604.0   6 247.0 0.371 828.0, 2510.0 -1.06
PL/J f 3287.0 421.0   6 172.0 0.128 2740.0, 3966.0 0.22
PL/J m 3362.0 922.0   5 412.0 0.274 2384.0, 4480.0 0.59


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1642.0 238.1433 2112.3549 1171.6451
129S1/SvImJ m 2301.3333 238.1433 2771.6882 1830.9785
A/J f 759.3333 238.1433 1229.6882 288.9785
A/J m 1310.0 238.1433 1780.3549 839.6451
AKR/J f 2936.3333 238.1433 3406.6882 2465.9785
AKR/J m 3114.8 260.8729 3630.048 2599.552
BALB/cByJ f 3025.2 260.8729 3540.448 2509.952
BALB/cByJ m 1610.0 238.1433 2080.3549 1139.6451
BTBR T+ Itpr3tf/J f 2528.6667 238.1433 2999.0215 2058.3118
BTBR T+ Itpr3tf/J m 2808.3333 238.1433 3278.6882 2337.9785
C3H/HeJ f 2470.0 238.1433 2940.3549 1999.6451
C3H/HeJ m 1969.0 238.1433 2439.3549 1498.6451
C57BL/6J f 3996.8333 168.3927 4329.4245 3664.2422
C57BL/6J m 3382.3333 168.3927 3714.9245 3049.7422
C57L/J f 5010.3333 238.1433 5480.6882 4539.9785
C57L/J m 4507.0 238.1433 4977.3549 4036.6451
DBA/2J f 2073.6667 168.3927 2406.2578 1741.0755
DBA/2J m 2184.8333 168.3927 2517.4245 1852.2422
FVB/NJ f 5184.4 260.8729 5699.648 4669.152
FVB/NJ m 4032.8 260.8729 4548.048 3517.552
NOD/ShiLtJ f 5084.0 238.1433 5554.3549 4613.6451
NOD/ShiLtJ m 4249.6667 238.1433 4720.0215 3779.3118
NZB/BlNJ f 1714.6667 238.1433 2185.0215 1244.3118
NZB/BlNJ m 1912.0 238.1433 2382.3549 1441.6451
PERA/EiJ f 1943.6 260.8729 2458.848 1428.352
PERA/EiJ m 1628.3333 238.1433 2098.6882 1157.9785
PL/J f 3287.3333 238.1433 3757.6882 2816.9785
PL/J m 3361.6 260.8729 3876.848 2846.352


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1971.6667 168.3927 2304.2578 1639.0755
A/J both 1034.6667 168.3927 1367.2578 702.0755
AKR/J both 3025.5667 176.6118 3374.3912 2676.7422
BALB/cByJ both 2317.6 176.6118 2666.4245 1968.7755
BTBR T+ Itpr3tf/J both 2668.5 168.3927 3001.0911 2335.9089
C3H/HeJ both 2219.5 168.3927 2552.0911 1886.9089
C57BL/6J both 3689.5833 119.0716 3924.7608 3454.4059
C57L/J both 4758.6667 168.3927 5091.2578 4426.0755
DBA/2J both 2129.25 119.0716 2364.4274 1894.0726
FVB/NJ both 4608.6 184.465 4972.9353 4244.2647
NOD/ShiLtJ both 4666.8333 168.3927 4999.4245 4334.2422
NZB/BlNJ both 1813.3333 168.3927 2145.9245 1480.7422
PERA/EiJ both 1785.9667 176.6118 2134.7912 1437.1422
PL/J both 3324.4667 176.6118 3673.2912 2975.6422




  GWAS USING LINEAR MIXED MODELS