Phenotype measure:   Kliethermes1   regression_activity_NP

ID, description, units MPD:59920   regression_activity_NP   residual score from regression of activity in novel compartment on total activity in novelty preference apparatus, 20 min test   [score]
Data set, strains Kliethermes1   inbred   14 strains     sex: both     age: 8wks
Procedure two chamber assay
Ontology mappings

  STRAIN COMPARISON PLOT
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Kliethermes1 - residual score from regression of activity in novel compartment on total activity in novelty preference apparatus, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means-196   score 107   score
Median of the strain means-42.4   score -14.0   score
SD of the strain means± 625 ± 709
Coefficient of variation (CV)-3.19 6.63
Min–max range of strain means-1576   –   677   score -1698   –   1228   score
Mean sample size per strain6.3   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3667715.5723 3667715.5723 3.2634 0.0728
strain 13 55673754.6168 4282596.509 3.8105 < 0.0001
sex:strain 13 15737064.3277 1210543.4098 1.0771 0.3827
Residuals 157 176453080.2952 1123904.97


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -622.0 991.0   6 405.0 -1.59 -1940.0, 629.0 -0.68
129S1/SvImJ m -228.0 1102.0   6 450.0 -4.83 -1260.0, 1602.0 -0.47
A/J f -1576.0 489.0   6 200.0 -0.31 -2118.0, -822.0 -2.21
A/J m -1698.0 1312.0   6 536.0 -0.773 -3132.0, -66.0 -2.54
AKR/J f 238.0 576.0   6 235.0 2.42 -513.0, 1233.0 0.69
AKR/J m 397.0 579.0   6 236.0 1.46 -286.0, 1219.0 0.41
BALB/cByJ f -1277.0 2773.0   5 1240.0 -2.17 -5367.0, 1275.0 -1.73
BALB/cByJ m 682.0 2342.0   6 956.0 3.43 -3886.0, 2559.0 0.81
BTBR T+ Itpr3tf/J f 50.8 1025.0   6 419.0 20.2 -917.0, 1676.0 0.39
BTBR T+ Itpr3tf/J m -71.8 1149.0   6 469.0 -16.0 -1645.0, 1862.0 -0.25
C3H/HeJ f -414.0 172.0   6 70.0 -0.414 -659.0, -164.0 -0.35
C3H/HeJ m -122.0 172.0   6 70.3 -1.41 -382.0, 132.0 -0.32
C57BL/6J f 241.0 1240.0   11 374.0 5.14 -1266.0, 1989.0 0.7
C57BL/6J m 637.0 921.0   12 266.0 1.45 -599.0, 2719.0 0.75
C57L/J f 413.0 1480.0   6 604.0 3.58 -1381.0, 2204.0 0.97
C57L/J m 1050.0 1553.0   6 634.0 1.48 -1332.0, 2918.0 1.33
DBA/2J f 141.0 770.0   12 222.0 5.44 -702.0, 1352.0 0.54
DBA/2J m 43.8 641.0   9 214.0 14.6 -952.0, 946.0 -0.09
FVB/NJ f 677.0 1064.0   6 434.0 1.57 -804.0, 1842.0 1.4
FVB/NJ m 82.2 464.0   6 190.0 5.65 -367.0, 873.0 -0.03
NOD/ShiLtJ f -0.617 790.0   6 323.0 -1281.0 -1022.0, 1297.0 0.31
NOD/ShiLtJ m 1228.0 1133.0   6 463.0 0.922 -57.8, 2907.0 1.58
NZB/BlNJ f -155.0 380.0   6 155.0 -2.45 -814.0, 253.0 0.07
NZB/BlNJ m -179.0 736.0   6 300.0 -4.12 -1321.0, 663.0 -0.4
PERA/EiJ f -84.2 645.0   5 288.0 -7.66 -1195.0, 484.0 0.18
PERA/EiJ m -242.0 681.0   6 278.0 -2.82 -1059.0, 512.0 -0.49
PL/J f -372.0 312.0   6 127.0 -0.838 -883.0, 2.62 -0.28
PL/J m -81.9 264.0   5 118.0 -3.22 -385.0, 333.0 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -622.05 432.8019 232.8156 -1476.9156
129S1/SvImJ m -228.3167 432.8019 626.549 -1083.1823
A/J f -1576.45 432.8019 -721.5844 -2431.3156
A/J m -1697.855 432.8019 -842.9894 -2552.7206
AKR/J f 237.6874 432.8019 1092.553 -617.1783
AKR/J m 396.6333 432.8019 1251.499 -458.2323
BALB/cByJ f -1277.02 474.1107 -340.5616 -2213.4784
BALB/cByJ m 682.4333 432.8019 1537.299 -172.4323
BTBR T+ Itpr3tf/J f 50.7667 432.8019 905.6323 -804.099
BTBR T+ Itpr3tf/J m -71.82 432.8019 783.0456 -926.6856
C3H/HeJ f -414.0167 432.8019 440.849 -1268.8823
C3H/HeJ m -122.3767 432.8019 732.489 -977.2423
C57BL/6J f 241.0545 319.6454 872.4147 -390.3056
C57BL/6J m 637.0367 306.0372 1241.518 32.5554
C57L/J f 413.1167 432.8019 1267.9823 -441.749
C57L/J m 1050.1 432.8019 1904.9656 195.2344
DBA/2J f 141.4333 306.0372 745.9146 -463.048
DBA/2J m 43.8004 353.3813 741.7953 -654.1944
FVB/NJ f 677.4833 432.8019 1532.349 -177.3823
FVB/NJ m 82.25 432.8019 937.1156 -772.6156
NOD/ShiLtJ f -0.6167 432.8019 854.249 -855.4823
NOD/ShiLtJ m 1228.37 432.8019 2083.2356 373.5044
NZB/BlNJ f -154.74 432.8019 700.1256 -1009.6056
NZB/BlNJ m -178.7333 432.8019 676.1323 -1033.599
PERA/EiJ f -84.158 474.1107 852.3004 -1020.6164
PERA/EiJ m -241.5967 432.8019 613.269 -1096.4623
PL/J f -372.38 432.8019 482.4856 -1227.2456
PL/J m -81.856 474.1107 854.6024 -1018.3144


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -425.1833 306.0372 179.298 -1029.6646
A/J both -1637.1525 306.0372 -1032.6712 -2241.6338
AKR/J both 317.1604 306.0372 921.6417 -287.3209
BALB/cByJ both -297.2933 320.9745 336.692 -931.2787
BTBR T+ Itpr3tf/J both -10.5267 306.0372 593.9546 -615.008
C3H/HeJ both -268.1967 306.0372 336.2846 -872.678
C57BL/6J both 439.0456 221.2645 876.0849 2.0064
C57L/J both 731.6083 306.0372 1336.0896 127.127
DBA/2J both 92.6169 233.7397 554.2971 -369.0633
FVB/NJ both 379.8667 306.0372 984.348 -224.6146
NOD/ShiLtJ both 613.8767 306.0372 1218.358 9.3954
NZB/BlNJ both -166.7367 306.0372 437.7446 -771.218
PERA/EiJ both -162.8773 320.9745 471.108 -796.8627
PL/J both -227.118 320.9745 406.8673 -861.1033




  GWAS USING LINEAR MIXED MODELS