Phenotype measure:   Kliethermes1   tot_activity_NP


  STRAIN COMPARISON PLOT
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Kliethermes1 - total activity (beam breaks) in novelty preference apparatus, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means4870   n 5109   n
Median of the strain means4341   n 4809   n
SD of the strain means± 2455 ± 2204
Coefficient of variation (CV)0.504 0.431
Min–max range of strain means1103   –   8985   n 1633   –   9060   n
Mean sample size per strain6.3   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5160888.6823 5160888.6823 5.1495 0.0246
strain 13 881921338.4385 67840102.9568 67.6907 < 0.0001
sex:strain 13 50540051.2596 3887696.2507 3.8791 < 0.0001
Residuals 157 157346603.998 1002207.6688


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1547.0 1306.0   6 533.0 0.844 16.0, 3468.0 -1.35
129S1/SvImJ m 3875.0 902.0   6 368.0 0.233 2460.0, 4982.0 -0.56
A/J f 1103.0 692.0   6 283.0 0.628 246.0, 2132.0 -1.53
A/J m 1633.0 593.0   6 242.0 0.363 994.0, 2576.0 -1.58
AKR/J f 4143.0 829.0   6 338.0 0.2 3310.0, 5620.0 -0.3
AKR/J m 4678.0 359.0   6 146.0 0.0767 4292.0, 5208.0 -0.2
BALB/cByJ f 4557.0 1765.0   5 789.0 0.387 1676.0, 5800.0 -0.13
BALB/cByJ m 4940.0 1363.0   6 556.0 0.276 2690.0, 6024.0 -0.08
BTBR T+ Itpr3tf/J f 5163.0 1306.0   6 533.0 0.253 3698.0, 7286.0 0.12
BTBR T+ Itpr3tf/J m 5929.0 900.0   6 367.0 0.152 4882.0, 7090.0 0.37
C3H/HeJ f 3464.0 356.0   6 145.0 0.103 3008.0, 3914.0 -0.57
C3H/HeJ m 3240.0 138.0   6 56.4 0.0426 2980.0, 3398.0 -0.85
C57BL/6J f 7755.0 1200.0   11 362.0 0.155 6082.0, 9332.0 1.18
C57BL/6J m 7609.0 1307.0   12 377.0 0.172 6342.0, 10002.0 1.13
C57L/J f 8804.0 946.0   6 386.0 0.108 6962.0, 9512.0 1.6
C57L/J m 9060.0 1047.0   6 428.0 0.116 7448.0, 10062.0 1.79
DBA/2J f 3660.0 954.0   12 275.0 0.261 1932.0, 5210.0 -0.49
DBA/2J m 5521.0 1054.0   9 351.0 0.191 4074.0, 7098.0 0.19
FVB/NJ f 7096.0 720.0   6 294.0 0.101 6340.0, 8078.0 0.91
FVB/NJ m 6739.0 975.0   6 398.0 0.145 5442.0, 8334.0 0.74
NOD/ShiLtJ f 8985.0 801.0   6 327.0 0.0891 7862.0, 9860.0 1.68
NOD/ShiLtJ m 8038.0 1086.0   6 443.0 0.135 6854.0, 9772.0 1.33
NZB/BlNJ f 3258.0 934.0   6 381.0 0.287 2084.0, 4920.0 -0.66
NZB/BlNJ m 3842.0 585.0   6 239.0 0.152 3052.0, 4398.0 -0.57
PERA/EiJ f 4104.0 506.0   5 226.0 0.123 3466.0, 4826.0 -0.31
PERA/EiJ m 1974.0 1552.0   6 634.0 0.786 12.0, 3470.0 -1.42
PL/J f 4539.0 527.0   6 215.0 0.116 3852.0, 5276.0 -0.13
PL/J m 4448.0 782.0   5 350.0 0.176 3552.0, 5456.0 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1547.0 408.6987 2354.2572 739.7428
129S1/SvImJ m 3875.3333 408.6987 4682.5905 3068.0761
A/J f 1102.6667 408.6987 1909.9239 295.4095
A/J m 1632.6667 408.6987 2439.9239 825.4095
AKR/J f 4143.3333 408.6987 4950.5905 3336.0761
AKR/J m 4678.0 408.6987 5485.2572 3870.7428
BALB/cByJ f 4557.2 447.707 5441.506 3672.894
BALB/cByJ m 4940.0 408.6987 5747.2572 4132.7428
BTBR T+ Itpr3tf/J f 5163.3333 408.6987 5970.5905 4356.0761
BTBR T+ Itpr3tf/J m 5929.3333 408.6987 6736.5905 5122.0761
C3H/HeJ f 3464.3333 408.6987 4271.5905 2657.0761
C3H/HeJ m 3240.3333 408.6987 4047.5905 2433.0761
C57BL/6J f 7755.0909 301.844 8351.2899 7158.892
C57BL/6J m 7609.3333 288.9936 8180.1504 7038.5163
C57L/J f 8804.3333 408.6987 9611.5905 7997.0761
C57L/J m 9060.0 408.6987 9867.2572 8252.7428
DBA/2J f 3660.5 288.9936 4231.317 3089.683
DBA/2J m 5520.8889 333.7011 6180.0116 4861.7661
FVB/NJ f 7096.3333 408.6987 7903.5905 6289.0761
FVB/NJ m 6739.0 408.6987 7546.2572 5931.7428
NOD/ShiLtJ f 8985.3333 408.6987 9792.5905 8178.0761
NOD/ShiLtJ m 8038.3333 408.6987 8845.5905 7231.0761
NZB/BlNJ f 3258.3333 408.6987 4065.5905 2451.0761
NZB/BlNJ m 3841.6667 408.6987 4648.9239 3034.4095
PERA/EiJ f 4103.6 447.707 4987.906 3219.294
PERA/EiJ m 1974.3333 408.6987 2781.5905 1167.0761
PL/J f 4538.6667 408.6987 5345.9239 3731.4095
PL/J m 4447.6 447.707 5331.906 3563.294


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2711.1667 288.9936 3281.9837 2140.3496
A/J both 1367.6667 288.9936 1938.4837 796.8496
AKR/J both 4410.6667 288.9936 4981.4837 3839.8496
BALB/cByJ both 4748.6 303.0991 5347.278 4149.922
BTBR T+ Itpr3tf/J both 5546.3333 288.9936 6117.1504 4975.5163
C3H/HeJ both 3352.3333 288.9936 3923.1504 2781.5163
C57BL/6J both 7682.2121 208.942 8094.9122 7269.5121
C57L/J both 8932.1667 288.9936 9502.9837 8361.3496
DBA/2J both 4590.6944 220.7225 5026.6632 4154.7257
FVB/NJ both 6917.6667 288.9936 7488.4837 6346.8496
NOD/ShiLtJ both 8511.8333 288.9936 9082.6504 7941.0163
NZB/BlNJ both 3550.0 288.9936 4120.817 2979.183
PERA/EiJ both 3038.9667 303.0991 3637.6446 2440.2887
PL/J both 4493.1333 303.0991 5091.8113 3894.4554




  GWAS USING LINEAR MIXED MODELS