Phenotype measure:   Kliethermes1   activity_novel_NP


  STRAIN COMPARISON PLOT
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Kliethermes1 - activity (beam breaks) in novel compartment of novelty preference apparatus, 20 min test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means2899   n 3169   n
Median of the strain means2596   n 3218   n
SD of the strain means± 1496 ± 1443
Coefficient of variation (CV)0.516 0.455
Min–max range of strain means269   –   5249   n 489   –   5687   n
Mean sample size per strain6.3   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4417818.3128 4417818.3128 6.1383 0.0143
strain 13 349130610.0961 26856200.7766 37.3151 < 0.0001
sex:strain 13 16208159.4158 1246781.4935 1.7323 0.0591
Residuals 157 112995204.0889 719714.6757


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 956.0 834.0   6 340.0 0.872 -1.3
129S1/SvImJ m 2363.0 905.0   6 369.0 0.383 1184.0, 3384.0 -0.56
A/J f 269.0 422.0   6 172.0 1.57 -1.76
A/J m 489.0 780.0   6 318.0 1.6 -1.86
AKR/J f 2725.0 487.0   6 199.0 0.179 2176.0, 3414.0 -0.12
AKR/J m 3081.0 411.0   6 168.0 0.133 2598.0, 3654.0 -0.06
BALB/cByJ f 2220.0 2052.0   5 918.0 0.924 -0.45
BALB/cByJ m 3354.0 1702.0   6 695.0 0.507 0.13
BTBR T+ Itpr3tf/J f 3170.0 1156.0   6 472.0 0.365 1942.0, 5056.0 0.18
BTBR T+ Itpr3tf/J m 3513.0 774.0   6 316.0 0.22 2944.0, 4750.0 0.24
C3H/HeJ f 2059.0 233.0   6 94.9 0.113 1842.0, 2414.0 -0.56
C3H/HeJ m 2081.0 75.6   6 30.9 0.0363 1996.0, 2220.0 -0.75
C57BL/6J f 4618.0 1058.0   11 319.0 0.229 3024.0, 5946.0 1.15
C57BL/6J m 4730.0 855.0   12 247.0 0.181 3656.0, 6048.0 1.08
C57L/J f 5249.0 509.0   6 208.0 0.097 4564.0, 5884.0 1.57
C57L/J m 5687.0 1051.0   6 429.0 0.185 3708.0, 6594.0 1.75
DBA/2J f 2427.0 658.0   12 190.0 0.271 1202.0, 3268.0 -0.32
DBA/2J m 3354.0 600.0   9 200.0 0.179 2544.0, 3968.0 0.13
FVB/NJ f 4481.0 852.0   6 348.0 0.19 3512.0, 5550.0 1.06
FVB/NJ m 4010.0 671.0   6 274.0 0.167 3204.0, 5222.0 0.58
NOD/ShiLtJ f 5147.0 700.0   6 286.0 0.136 4072.0, 5796.0 1.5
NOD/ShiLtJ m 5237.0 978.0   6 399.0 0.187 4340.0, 6944.0 1.43
NZB/BlNJ f 2075.0 619.0   6 253.0 0.298 1146.0, 3012.0 -0.55
NZB/BlNJ m 2369.0 449.0   6 183.0 0.19 1784.0, 2962.0 -0.55
PERA/EiJ f 2551.0 525.0   5 235.0 0.206 1688.0, 3020.0 -0.23
PERA/EiJ m 1361.0 1114.0   6 455.0 0.818 -1.25
PL/J f 2642.0 324.0   6 132.0 0.123 2270.0, 2998.0 -0.17
PL/J m 2732.0 390.0   5 174.0 0.143 2280.0, 3116.0 -0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 956.3333 346.3415 1640.4233 272.2433
129S1/SvImJ m 2363.0 346.3415 3047.09 1678.91
A/J f 269.0 346.3415 953.09 -415.09
A/J m 488.6667 346.3415 1172.7567 -195.4233
AKR/J f 2725.3333 346.3415 3409.4233 2041.2433
AKR/J m 3081.0 346.3415 3765.09 2396.91
BALB/cByJ f 2220.4 379.3981 2969.7831 1471.0169
BALB/cByJ m 3354.3333 346.3415 4038.4233 2670.2433
BTBR T+ Itpr3tf/J f 3170.3333 346.3415 3854.4233 2486.2433
BTBR T+ Itpr3tf/J m 3513.0 346.3415 4197.09 2828.91
C3H/HeJ f 2059.3333 346.3415 2743.4233 1375.2433
C3H/HeJ m 2081.0 346.3415 2765.09 1396.91
C57BL/6J f 4618.0 255.7902 5123.234 4112.766
C57BL/6J m 4730.3333 244.9004 5214.058 4246.6086
C57L/J f 5249.3333 346.3415 5933.4233 4565.2433
C57L/J m 5686.6667 346.3415 6370.7567 5002.5767
DBA/2J f 2426.6667 244.9004 2910.3914 1942.942
DBA/2J m 3354.2222 282.7867 3912.7794 2795.6651
FVB/NJ f 4481.0 346.3415 5165.09 3796.91
FVB/NJ m 4010.3333 346.3415 4694.4233 3326.2433
NOD/ShiLtJ f 5147.0 346.3415 5831.09 4462.91
NOD/ShiLtJ m 5236.6667 346.3415 5920.7567 4552.5767
NZB/BlNJ f 2075.0 346.3415 2759.09 1390.91
NZB/BlNJ m 2369.0 346.3415 3053.09 1684.91
PERA/EiJ f 2551.2 379.3981 3300.5831 1801.8169
PERA/EiJ m 1361.3333 346.3415 2045.4233 677.2433
PL/J f 2641.6667 346.3415 3325.7567 1957.5767
PL/J m 2732.4 379.3981 3481.7831 1983.0169


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1659.6667 244.9004 2143.3914 1175.942
A/J both 378.8333 244.9004 862.558 -104.8914
AKR/J both 2903.1667 244.9004 3386.8914 2419.442
BALB/cByJ both 2787.3667 256.8537 3294.7014 2280.0319
BTBR T+ Itpr3tf/J both 3341.6667 244.9004 3825.3914 2857.942
C3H/HeJ both 2070.1667 244.9004 2553.8914 1586.442
C57BL/6J both 4674.1667 177.0627 5023.899 4324.4343
C57L/J both 5468.0 244.9004 5951.7247 4984.2753
DBA/2J both 2890.4444 187.0458 3259.8953 2520.9936
FVB/NJ both 4245.6667 244.9004 4729.3914 3761.942
NOD/ShiLtJ both 5191.8333 244.9004 5675.558 4708.1086
NZB/BlNJ both 2222.0 244.9004 2705.7247 1738.2753
PERA/EiJ both 1956.2667 256.8537 2463.6014 1448.9319
PL/J both 2687.0333 256.8537 3194.3681 2179.6986




  GWAS USING LINEAR MIXED MODELS