Project measure / variable:   Jentsch2   infusions4_FR2

ID, description, units MPD:49716   infusions4_FR2   Fixed ratio 2 - self administration: number of infusions earned   [n]  day 4  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 2 - self administration: number of infusions earned day 4



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means38.2   n 35.5   n
Median of the strain means38.2   n 36.8   n
SD of the strain means± 6.08 ± 12.3
Coefficient of variation (CV)0.159 0.348
Min–max range of strain means33.9   –   42.5   n 19.9   –   48.5   n
Mean sample size per strain4.5   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 7.255 7.255 0.09 0.7675
strain 1 808.5057 808.5057 10.0242 0.0051
sex:strain 1 57.5213 57.5213 0.7132 0.4089
Residuals 19 1532.4571 80.6556


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 19.9 4.71   7 1.78 0.237 13.0, 27.0 -1.27
BXD38/TyJ f 33.9 8.59   7 3.25 0.254 21.0, 48.0 -0.71
BXD38/TyJ m 32.3 8.64   10 2.73 0.268 10.0, 40.0 -0.26
BXD42/TyJ m 41.4 5.24   11 1.58 0.127 32.0, 50.0 0.48
BXD68/RwwJ f 42.5 2.12   2   1.5 0.0499 41.0, 44.0 0.71
BXD68/RwwJ m 48.5 11.7   4 5.87 0.242 38.0, 64.0 1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 33.8571 3.3944 40.9618 26.7525
BXD38/TyJ m 32.3 2.84 38.2442 26.3558
BXD68/RwwJ f 42.5 6.3504 55.7916 29.2084
BXD68/RwwJ m 48.5 4.4904 57.8986 39.1014


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 33.0786 2.2129 37.7102 28.4469
BXD68/RwwJ both 45.5 3.8888 53.6394 37.3606




GWAS analysis not available: SNP data is not available for enough strains (at least 4)