Project measure / variable:   Jentsch2   infusions3_FR1

ID, description, units MPD:49703   infusions3_FR1   Fixed ratio 1 - self administration: number of infusions earned   [n]  day 3  
cocaine study
Data set, strains Jentsch2   BXD   4 strains     sex: both     age: 8-17wks
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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Jentsch2 - Fixed ratio 1 - self administration: number of infusions earned day 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested2 strains4 strains
Mean of the strain means19.0   n 18.3   n
Median of the strain means19.0   n 20.2   n
SD of the strain means± 22.0 ± 8.82
Coefficient of variation (CV)1.16 0.481
Min–max range of strain means3.43   –   34.5   n 6.36   –   26.4   n
Mean sample size per strain4.5   mice 10.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2963 0.2963 0.0051 0.9439
strain 1 2181.1217 2181.1217 37.2653 < 0.0001
sex:strain 1 208.4775 208.4775 3.5619 0.0718
Residuals 23 1346.1786 58.5295


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD31/TyJ m 17.3 13.6   10 4.29 0.785 2.0, 37.0 -0.12
BXD38/TyJ f 3.43 4.35   7 1.65 1.27 -0.71
BXD38/TyJ m 6.36 5.56   14 1.48 0.874 -1.36
BXD42/TyJ m 26.4 19.4   14 5.18 0.734 2.0, 64.0 0.92
BXD68/RwwJ f 34.5 21.9   2   15.5 0.635 19.0, 50.0 0.71
BXD68/RwwJ m 23.2 10.8   4 5.41 0.465 10.0, 36.0 0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ f 3.4286 2.8916 9.4103 0.0
BXD38/TyJ m 6.3571 2.0447 10.5869 2.1274
BXD68/RwwJ f 34.5 5.4097 45.6908 23.3092
BXD68/RwwJ m 23.25 3.8252 31.1631 15.3369


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD38/TyJ both 4.8929 1.7707 8.5559 1.2298
BXD68/RwwJ both 28.875 3.3127 35.7279 22.0221




GWAS analysis not available: SNP data is not available for enough strains (at least 4)