Project measure / variable:   Gould3   EPM_pct_open_12

ID, description, units MPD:47329   EPM_pct_open_12   withdrawal study group, percentage of time in open arms   [%]  dose: 12 mg  
nicotine study
Data set, strains Gould3   inbred   8 strains     sex: m     age: 8-12wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Gould3 - withdrawal study group, percentage of time in open arms dose: 12 mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means45.0   %
Median of the strain means48.1   %
SD of the strain means± 21.7
Coefficient of variation (CV)0.483
Min–max range of strain means15.4   –   69.9   %
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 32397.0607 4628.1515 27.6735 < 0.0001
Residuals 70 11706.9028 167.2415


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 24.6 11.2   10 3.55 0.457 8.53, 40.0 -0.94
A/J m 69.9 23.6   10 7.47 0.338 30.3, 99.9 1.14
BALB/cByJ m 61.7 13.2   10 4.18 0.214 46.3, 89.9 0.77
C3H/HeJ m 61.6 4.99   9 1.66 0.081 53.4, 70.2 0.76
C57BL/6J m 27.0 7.32   10 2.31 0.271 12.8, 38.0 -0.83
CBA/J m 65.3 14.4   9 4.78 0.22 49.5, 91.2 0.93
DBA/1J m 34.6 11.7   10 3.71 0.339 19.1, 52.0 -0.48
DBA/2J m 15.4 6.78   10 2.15 0.44 7.04, 27.6 -1.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 24.583 4.0895 32.7393 16.4267
A/J m 69.863 4.0895 78.0193 61.7067
BALB/cByJ m 61.729 4.0895 69.8853 53.5727
C3H/HeJ m 61.5633 4.3107 70.1608 52.9659
C57BL/6J m 27.002 4.0895 35.1583 18.8457
CBA/J m 65.34 4.3107 73.9375 56.7425
DBA/1J m 34.639 4.0895 42.7953 26.4827
DBA/2J m 15.404 4.0895 23.5603 7.2477




  GWAS USING LINEAR MIXED MODELS