Project measure / variable:   Gould3   EPM_pct_open_6

ID, description, units MPD:47328   EPM_pct_open_6   withdrawal study group, percentage of time in open arms   [%]  dose: 6.3 mg  
nicotine study
Data set, strains Gould3   inbred   8 strains     sex: m     age: 8-12wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Gould3 - withdrawal study group, percentage of time in open arms dose: 6.3 mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means40.7   %
Median of the strain means39.4   %
SD of the strain means± 17.7
Coefficient of variation (CV)0.436
Min–max range of strain means15.2   –   64.7   %
Mean sample size per strain9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 20936.8989 2990.9856 15.5323 < 0.0001
Residuals 69 13287.0531 192.566


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 25.4 17.8   9 5.94 0.701 10.2, 68.9 -0.86
A/J m 45.2 17.4   10 5.49 0.384 17.9, 70.4 0.25
BALB/cByJ m 55.8 13.8   10 4.36 0.247 35.9, 75.2 0.85
C3H/HeJ m 57.7 13.6   9 4.52 0.235 38.0, 78.5 0.96
C57BL/6J m 28.3 13.2   10 4.19 0.468 13.0, 56.0 -0.7
CBA/J m 64.7 10.5   9 3.5 0.162 43.0, 76.1 1.35
DBA/1J m 33.5 13.5   10 4.28 0.404 13.9, 56.3 -0.41
DBA/2J m 15.2 9.06   10 2.87 0.597 3.15, 30.9 -1.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 25.4278 4.6256 34.6556 16.1999
A/J m 45.175 4.3882 53.9293 36.4207
BALB/cByJ m 55.823 4.3882 64.5773 47.0687
C3H/HeJ m 57.69 4.6256 66.9178 48.4622
C57BL/6J m 28.272 4.3882 37.0263 19.5177
CBA/J m 64.6911 4.6256 73.9189 55.4633
DBA/1J m 33.484 4.3882 42.2383 24.7297
DBA/2J m 15.176 4.3882 23.9303 6.4217




  GWAS USING LINEAR MIXED MODELS