Project measure / variable:   Gould3   EPM_pct_closed_12

ID, description, units MPD:47324   EPM_pct_closed_12   withdrawal study group, percentage of time in closed arms   [%]  dose: 12 mg  
nicotine study
Data set, strains Gould3   inbred   8 strains     sex: m     age: 8-12wks
Procedure elevated plus maze
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  STRAIN COMPARISON PLOT
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Gould3 - withdrawal study group, percentage of time in closed arms dose: 12 mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means36.1   %
Median of the strain means31.3   %
SD of the strain means± 19.5
Coefficient of variation (CV)0.538
Min–max range of strain means15.1   –   71.6   %
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 26179.5309 3739.933 17.2152 < 0.0001
Residuals 70 15207.242 217.2463


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 36.9 23.2   10 7.35 0.629 8.88, 66.9 0.04
A/J m 15.1 18.4   10 5.82 1.22 -1.08
BALB/cByJ m 21.7 10.9   10 3.46 0.505 2.76, 38.9 -0.74
C3H/HeJ m 25.7 4.69   9 1.56 0.183 21.2, 35.7 -0.54
C57BL/6J m 55.8 9.34   10 2.95 0.167 42.7, 73.9 1.01
CBA/J m 21.3 14.0   9 4.66 0.656 -0.76
DBA/1J m 41.1 17.7   10 5.61 0.432 9.13, 64.1 0.25
DBA/2J m 71.6 9.8   10 3.1 0.137 59.1, 86.1 1.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 36.925 4.661 46.221 27.629
A/J m 15.071 4.661 24.367 5.775
BALB/cByJ m 21.678 4.661 30.974 12.382
C3H/HeJ m 25.6889 4.9131 35.4877 15.89
C57BL/6J m 55.779 4.661 65.075 46.483
CBA/J m 21.3011 4.9131 31.1 11.5023
DBA/1J m 41.08 4.661 50.376 31.784
DBA/2J m 71.616 4.661 80.912 62.32




  GWAS USING LINEAR MIXED MODELS