Project measure / variable:   Crowley1   haloperidol_d60

ID, description, units MPD:39404   haloperidol_d60   plasma haloperidol concentration   [nM]  on day 60  
haloperidol study
Data set, strains Crowley1   inbred w/CC8   27 strains     sex: m     age: 9-28wks
Procedure drug and metabolite quantification
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  STRAIN COMPARISON PLOT
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Crowley1 - plasma haloperidol concentration on day 60



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested27 strains
Mean of the strain means21.9   nM
Median of the strain means20.1   nM
SD of the strain means± 9.19
Coefficient of variation (CV)0.420
Min–max range of strain means9.55   –   49.6   nM
Mean sample size per strain5.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 26 12796.8309 492.1858 11.8574 < 0.0001
Residuals 131 5437.6271 41.5086


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 19.0 2.13   8 0.753 0.112 16.4, 22.3 -0.31
A/J m 19.9 4.15   5 1.86 0.209 15.0, 25.9 -0.22
AKR/J m 11.0 2.11   5 0.942 0.192 8.6, 14.2 -1.18
BALB/cByJ m 9.55 0.827   4 0.413 0.0866 8.7, 10.4 -1.34
BTBR T+ Itpr3tf/J m 30.3 4.17   8 1.47 0.138 24.3, 37.4 0.92
C3H/HeJ m 15.9 4.09   5 1.83 0.256 12.2, 21.7 -0.65
C57BL/6J m 10.5 2.4   5 1.07 0.23 8.2, 14.3 -1.24
C57BLKS/J m 20.8 3.06   5 1.37 0.147 17.2, 24.6 -0.12
CAST/EiJ m 17.9 6.21   5 2.78 0.348 12.0, 28.0 -0.43
CBA/J m 15.6 3.89   5 1.74 0.25 11.0, 20.7 -0.68
DBA/2J m 16.9 3.54   9 1.18 0.209 11.0, 20.8 -0.54
DDY/JclSidSeyFrkJ m 25.9 10.9   7 4.11 0.42 12.0, 46.8 0.44
FVB/NJ m 21.9 2.47   5 1.1 0.112 19.5, 25.8 0.0
KK/HlJ m 24.3 9.19   7 3.47 0.377 10.4, 40.9 0.26
MA/MyJ m 17.6 1.57   6 0.642 0.0891 16.2, 20.1 -0.47
MOLF/EiJ m 20.0 3.14   5 1.4 0.157 16.5, 24.9 -0.2
MRL/MpJ m 17.8 2.5   5 1.12 0.141 14.7, 20.5 -0.44
MSM/MsJ m 22.0 5.47   6 2.23 0.248 14.7, 30.5 0.01
NOD/ShiLtJ m 16.1 2.13   5 0.954 0.132 12.4, 17.7 -0.63
NON/ShiLtJ m 22.1 6.41   8 2.27 0.29 15.1, 34.0 0.02
NZL/LtJ m 49.6 18.1   8 6.39 0.364 18.9, 80.4 3.02
NZO/HlLtJ m 48.3 10.4   4 5.18 0.215 37.3, 61.5 2.88
NZW/LacJ m 24.0 2.69   5 1.2 0.112 19.9, 27.0 0.23
PWK/PhJ m 24.8 4.73   5 2.11 0.19 18.0, 30.4 0.32
SJL/J m 22.7 2.93   5 1.31 0.129 18.7, 26.0 0.09
SM/J m 20.1 3.17   8 1.12 0.158 16.2, 25.5 -0.19
WSB/EiJ m 26.1 6.13   5 2.74 0.235 20.9, 35.7 0.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 19.025 2.2778 23.5311 14.5189
A/J m 19.86 2.8813 25.5598 14.1602
AKR/J m 10.96 2.8813 16.6598 5.2602
BALB/cByJ m 9.55 3.2214 15.9226 3.1774
BTBR T+ Itpr3tf/J m 30.275 2.2778 34.7811 25.7689
C3H/HeJ m 15.94 2.8813 21.6398 10.2402
C57BL/6J m 10.46 2.8813 16.1598 4.7602
C57BLKS/J m 20.8 2.8813 26.4998 15.1002
CAST/EiJ m 17.86 2.8813 23.5598 12.1602
CBA/J m 15.56 2.8813 21.2598 9.8602
DBA/2J m 16.9444 2.1476 21.1929 12.696
DDY/JclSidSeyFrkJ m 25.9 2.4351 30.7172 21.0828
FVB/NJ m 21.94 2.8813 27.6398 16.2402
KK/HlJ m 24.3429 2.4351 29.1601 19.5256
MA/MyJ m 17.65 2.6302 22.8532 12.4468
MOLF/EiJ m 20.0 2.8813 25.6998 14.3002
MRL/MpJ m 17.76 2.8813 23.4598 12.0602
MSM/MsJ m 22.05 2.6302 27.2532 16.8468
NOD/ShiLtJ m 16.12 2.8813 21.8198 10.4202
NON/ShiLtJ m 22.15 2.2778 26.6561 17.6439
NZL/LtJ m 49.5625 2.2778 54.0686 45.0564
NZO/HlLtJ m 48.3 3.2214 54.6726 41.9274
NZW/LacJ m 23.96 2.8813 29.6598 18.2602
PWK/PhJ m 24.82 2.8813 30.5198 19.1202
SJL/J m 22.72 2.8813 28.4198 17.0202
SM/J m 20.075 2.2778 24.5811 15.5689
WSB/EiJ m 26.14 2.8813 31.8398 20.4402




  GWAS USING LINEAR MIXED MODELS