Project measure / variable:   Rusyn2   DCV_cysteine2_tce

ID, description, units MPD:36185   DCV_cysteine2_tce   DCV cysteine (serum DCVC x 10-3)   [nmol/mL]  2h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - DCV cysteine (serum DCVC x 10-3) 2h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means1.37   nmol/mL
Median of the strain means1.34   nmol/mL
SD of the strain means± 0.735
Coefficient of variation (CV)0.535
Min–max range of strain means0.485   –   2.68   nmol/mL
Mean sample size per strain2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 11 15.9446 1.4495 1.6106 0.1783
Residuals 18 16.1993 0.9


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.9 1.65   2   1.17 0.871 0.73, 3.07 0.72
A/J m 0.77 0.0   1   0.0 0.0 0.77, 0.77 -0.82
B6C3F1/J m 2.43 0.874   3 0.505 0.36 1.45, 3.13 1.44
BALB/cByJ m 0.748 0.0665   2   0.047 0.0889 0.701, 0.795 -0.85
BTBR T+ Itpr3tf/J m 0.571 0.101   3 0.0581 0.176 0.498, 0.686 -1.09
C3H/HeJ m 1.34 0.42   3 0.242 0.314 0.902, 1.74 -0.05
C57BL/6J m 2.68 1.63   3 0.941 0.609 1.36, 4.5 1.78
CAST/EiJ m 1.35 1.17   2   0.83 0.869 0.52, 2.18 -0.03
DBA/2J m 0.977 0.612   2   0.433 0.627 0.544, 1.41 -0.54
FVB/NJ m 2.14 1.48   3 0.854 0.692 0.839, 3.75 1.04
KK/HlJ m 0.485 0.00707   2   0.005 0.0146 0.48, 0.49 -1.21
MOLF/EiJ m 0.722 0.0   2   0.0 0.0 0.722, 0.722 -0.89
NOD/ShiLtJ m 2.21 0.0   1   0.0 0.0 2.21, 2.21 1.14
NZW/LacJ m 1.52 0.231   3 0.133 0.152 1.25, 1.66 0.2
PWD/PhJ m 0.76 0.0   1   0.0 0.0 0.76, 0.76 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1.9 0.6708 3.3093 0.4907
B6C3F1/J m 2.43 0.5477 3.5807 1.2793
BALB/cByJ m 0.748 0.6708 2.1573 0.0
BTBR T+ Itpr3tf/J m 0.5713 0.5477 1.722 0.0
C3H/HeJ m 1.3373 0.5477 2.488 0.1866
C57BL/6J m 2.6767 0.5477 3.8274 1.526
CAST/EiJ m 1.35 0.6708 2.7593 0.0
DBA/2J m 0.977 0.6708 2.3863 0.0
FVB/NJ m 2.1397 0.5477 3.2904 0.989
KK/HlJ m 0.485 0.6708 1.8943 0.0
MOLF/EiJ m 0.722 0.6708 2.1313 0.0
NZW/LacJ m 1.5167 0.5477 2.6674 0.366




  GWAS USING LINEAR MIXED MODELS