Project measure / variable:   Rusyn2   TCA_2_tce

ID, description, units MPD:36175   TCA_2_tce   trichloroacetic acid (serum TCA)   [nmol/mL]  2h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - trichloroacetic acid (serum TCA) 2h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means277   nmol/mL
Median of the strain means257   nmol/mL
SD of the strain means± 53.3
Coefficient of variation (CV)0.192
Min–max range of strain means213   –   397   nmol/mL
Mean sample size per strain2.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 88556.7193 6812.0553 0.5912 0.8374
Residuals 24 276529.8333 11522.0764


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 213.0 148.0   2   105.0 0.697 108.0, 318.0 -1.21
A/J m 308.0 0.0   1   0.0 0.0 308.0, 308.0 0.57
B6C3F1/J m 254.0 30.0   3 17.3 0.118 224.0, 284.0 -0.44
BALB/cByJ m 360.0 55.9   2   39.5 0.155 320.0, 399.0 1.55
BTBR T+ Itpr3tf/J m 252.0 49.7   3 28.7 0.197 198.0, 296.0 -0.47
C3H/HeJ m 243.0 27.9   3 16.1 0.115 218.0, 273.0 -0.64
C57BL/6J m 219.0 21.0   3 12.1 0.0961 198.0, 240.0 -1.09
CAST/EiJ m 249.0 66.2   3 38.2 0.266 207.0, 325.0 -0.53
DBA/2J m 257.0 6.56   3 3.79 0.0255 251.0, 264.0 -0.38
FVB/NJ m 266.0 35.8   3 20.7 0.135 225.0, 291.0 -0.21
KK/HlJ m 327.0 48.4   3 27.9 0.148 291.0, 382.0 0.93
MOLF/EiJ m 233.0 0.0   2   0.0 0.0 233.0, 233.0 -0.83
NOD/ShiLtJ m 262.0 258.0   3 149.0 0.985 113.0, 560.0 -0.29
NZW/LacJ m 320.0 75.1   3 43.3 0.235 247.0, 397.0 0.8
PWD/PhJ m 397.0 286.0   2   202.0 0.72 195.0, 599.0 2.24


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 213.0 75.9015 369.653 56.347
B6C3F1/J m 254.3333 61.9733 382.24 126.4267
BALB/cByJ m 359.5 75.9015 516.153 202.847
BTBR T+ Itpr3tf/J m 251.6667 61.9733 379.5733 123.76
C3H/HeJ m 242.6667 61.9733 370.5733 114.76
C57BL/6J m 218.6667 61.9733 346.5733 90.76
CAST/EiJ m 248.6667 61.9733 376.5733 120.76
DBA/2J m 257.0 61.9733 384.9066 129.0934
FVB/NJ m 266.0 61.9733 393.9066 138.0934
KK/HlJ m 327.0 61.9733 454.9066 199.0934
MOLF/EiJ m 233.0 75.9015 389.653 76.347
NOD/ShiLtJ m 262.0 61.9733 389.9066 134.0934
NZW/LacJ m 320.0 61.9733 447.9066 192.0934
PWD/PhJ m 397.0 75.9015 553.653 240.347




  GWAS USING LINEAR MIXED MODELS