Project measure / variable:   Rusyn2   AST_24_ctrl

ID, description, units MPD:36124   AST_24_ctrl   aspartate transaminase (serum AST), control group   [IU/L]  24h after baseline  
trichloroethylene study
Data set, strains Rusyn2   inbred   15 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), control group 24h after baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested15 strains
Mean of the strain means196   IU/L
Median of the strain means177   IU/L
SD of the strain means± 118
Coefficient of variation (CV)0.602
Min–max range of strain means53.3   –   442   IU/L
Mean sample size per strain2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 558250.8643 39875.0617 1.712 0.1099
Residuals 28 652151.8333 23291.1369


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 64.7 4.62   3 2.67 0.0714 62.0, 70.0 -1.11
A/J m 195.0 73.2   3 42.3 0.376 114.0, 257.0 -0.01
AKR/J m 78.3 22.2   3 12.8 0.283 60.0, 103.0 -1.0
B6C3F1/J m 177.0 161.0   3 93.1 0.911 75.0, 363.0 -0.16
BALB/cByJ m 345.0 358.0   2   253.0 1.04 92.0, 598.0 1.27
BTBR T+ Itpr3tf/J m 53.3 4.16   3 2.4 0.0781 50.0, 58.0 -1.21
C3H/HeJ m 231.0 140.0   3 80.9 0.606 146.0, 393.0 0.3
C57BL/6J m 91.3 9.02   3 5.21 0.0987 82.0, 100.0 -0.89
DBA/2J m 142.0 10.6   2   7.5 0.0744 135.0, 150.0 -0.46
FVB/NJ m 119.0 10.6   3 6.12 0.0888 108.0, 129.0 -0.65
KK/HlJ m 244.0 132.0   3 76.4 0.542 147.0, 395.0 0.41
MOLF/EiJ m 442.0 331.0   3 191.0 0.75 150.0, 802.0 2.09
NOD/ShiLtJ m 246.0 60.0   3 34.6 0.244 206.0, 315.0 0.43
NZW/LacJ m 136.0 15.0   3 8.69 0.111 126.0, 153.0 -0.51
PWD/PhJ m 371.0 281.0   3 162.0 0.758 83.0, 645.0 1.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 64.6667 88.1119 245.1558 0.0
A/J m 194.6667 88.1119 375.1558 14.1776
AKR/J m 78.3333 88.1119 258.8224 0.0
B6C3F1/J m 177.0 88.1119 357.4891 0.0
BALB/cByJ m 345.0 107.9146 566.0531 123.9469
BTBR T+ Itpr3tf/J m 53.3333 88.1119 233.8224 0.0
C3H/HeJ m 231.3333 88.1119 411.8224 50.8442
C57BL/6J m 91.3333 88.1119 271.8224 0.0
DBA/2J m 142.5 107.9146 363.5531 0.0
FVB/NJ m 119.3333 88.1119 299.8224 0.0
KK/HlJ m 244.3333 88.1119 424.8224 63.8442
MOLF/EiJ m 441.6667 88.1119 622.1558 261.1776
NOD/ShiLtJ m 246.0 88.1119 426.4891 65.5109
NZW/LacJ m 135.6667 88.1119 316.1558 0.0
PWD/PhJ m 371.3333 88.1119 551.8224 190.8442




  GWAS USING LINEAR MIXED MODELS