Project measure / variable:   Rusyn2   AST_8_ctrl

ID, description, units MPD:36123   AST_8_ctrl   aspartate transaminase (serum AST), control group   [IU/L]  8h after baseline  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - aspartate transaminase (serum AST), control group 8h after baseline



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means148   IU/L
Median of the strain means132   IU/L
SD of the strain means± 69.1
Coefficient of variation (CV)0.468
Min–max range of strain means64.3   –   346   IU/L
Mean sample size per strain2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 14 196659.9612 14047.1401 0.9008 0.5674
Residuals 28 436643.6667 15594.4167


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 94.7 30.6   3 17.7 0.323 76.0, 130.0 -0.77
A/J m 209.0 132.0   3 76.2 0.632 123.0, 361.0 0.88
AKR/J m 111.0 16.5   3 9.53 0.149 94.0, 127.0 -0.53
B6C3F1/J m 64.3 36.1   3 20.8 0.561 43.0, 106.0 -1.21
BALB/cByJ m 346.0 432.0   3 249.0 1.25 91.0, 844.0 2.87
BTBR T+ Itpr3tf/J m 83.3 22.1   3 12.8 0.266 58.0, 99.0 -0.93
C3H/HeJ m 111.0 19.7   3 11.4 0.178 88.0, 124.0 -0.53
C57BL/6J m 106.0 14.0   3 8.11 0.132 93.0, 121.0 -0.6
DBA/2J m 138.0 29.5   3 17.0 0.214 119.0, 172.0 -0.14
FVB/NJ m 125.0 27.9   3 16.1 0.223 106.0, 157.0 -0.33
KK/HlJ m 178.0 10.6   2   7.5 0.0598 170.0, 185.0 0.44
MOLF/EiJ m 152.0 2.12   2   1.5 0.014 150.0, 153.0 0.06
NOD/ShiLtJ m 180.0 8.19   3 4.73 0.0455 173.0, 189.0 0.47
NZW/LacJ m 98.0 12.5   3 7.21 0.127 84.0, 108.0 -0.72
PWD/PhJ m 149.0 95.4   3 55.1 0.64 81.0, 258.0 0.02
WSB/EiJ m 220.0 0.0   1   0.0 0.0 220.0, 220.0 1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 94.6667 72.0981 242.353 0.0
A/J m 209.0 72.0981 356.6863 61.3137
AKR/J m 110.6667 72.0981 258.353 0.0
B6C3F1/J m 64.3333 72.0981 212.0196 0.0
BALB/cByJ m 345.6667 72.0981 493.353 197.9804
BTBR T+ Itpr3tf/J m 83.3333 72.0981 231.0196 0.0
C3H/HeJ m 110.6667 72.0981 258.353 0.0
C57BL/6J m 106.3333 72.0981 254.0196 0.0
DBA/2J m 138.0 72.0981 285.6863 0.0
FVB/NJ m 125.0 72.0981 272.6863 0.0
KK/HlJ m 177.5 88.3018 358.378 0.0
MOLF/EiJ m 151.5 88.3018 332.378 0.0
NOD/ShiLtJ m 180.0 72.0981 327.6863 32.3137
NZW/LacJ m 98.0 72.0981 245.6863 0.0
PWD/PhJ m 149.0 72.0981 296.6863 1.3137




  GWAS USING LINEAR MIXED MODELS