Project measure / variable:   Rusyn2   ALT_24_tce

ID, description, units MPD:36119   ALT_24_tce   alanine transaminase (serum ALT), treated group   [IU/L]  24h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - alanine transaminase (serum ALT), treated group 24h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means55.5   IU/L
Median of the strain means44.0   IU/L
SD of the strain means± 36.1
Coefficient of variation (CV)0.652
Min–max range of strain means11.9   –   134   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 15 58359.5698 3890.638 2.4259 0.0181
Residuals 31 49717.7983 1603.7999


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 86.9 38.5   3 22.2 0.443 55.9, 130.0 0.87
A/J m 39.0 4.74   2   3.35 0.122 35.6, 42.3 -0.46
AKR/J m 11.9 7.65   3 4.42 0.641 6.6, 20.7 -1.21
B6C3F1/J m 134.0 72.0   3 41.6 0.538 81.6, 216.0 2.17
BALB/cByJ m 49.3 18.3   3 10.5 0.371 35.2, 69.9 -0.17
BTBR T+ Itpr3tf/J m 39.1 12.6   3 7.29 0.323 25.0, 49.3 -0.45
C3H/HeJ m 75.8 60.1   3 34.7 0.793 37.7, 145.0 0.56
C57BL/6J m 35.1 17.9   3 10.3 0.509 19.6, 54.7 -0.56
CAST/EiJ m 129.0 102.0   3 58.9 0.791 35.8, 238.0 2.04
DBA/2J m 23.6 0.52   3 0.3 0.022 23.0, 23.9 -0.88
FVB/NJ m 73.2 37.9   3 21.9 0.518 44.1, 116.0 0.49
KK/HlJ m 36.8 30.2   3 17.4 0.821 18.0, 71.6 -0.52
MOLF/EiJ m 27.6 8.93   3 5.15 0.323 17.6, 34.7 -0.77
NOD/ShiLtJ m 56.5 20.0   3 11.5 0.353 33.5, 69.4 0.03
NZW/LacJ m 20.6 12.6   3 7.29 0.613 12.1, 35.1 -0.96
PWD/PhJ m 48.9 17.5   3 10.1 0.358 36.8, 69.0 -0.18


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 86.9333 23.1214 134.0898 39.7769
A/J m 38.95 28.3178 96.7046 0.0
AKR/J m 11.9333 23.1214 59.0898 0.0
B6C3F1/J m 133.8667 23.1214 181.0231 86.7102
BALB/cByJ m 49.2667 23.1214 96.4231 2.1102
BTBR T+ Itpr3tf/J m 39.1333 23.1214 86.2898 0.0
C3H/HeJ m 75.7667 23.1214 122.9231 28.6102
C57BL/6J m 35.1333 23.1214 82.2898 0.0
CAST/EiJ m 128.9333 23.1214 176.0898 81.7769
DBA/2J m 23.6 23.1214 70.7564 0.0
FVB/NJ m 73.1667 23.1214 120.3231 26.0102
KK/HlJ m 36.7667 23.1214 83.9231 0.0
MOLF/EiJ m 27.6333 23.1214 74.7898 0.0
NOD/ShiLtJ m 56.5 23.1214 103.6564 9.3436
NZW/LacJ m 20.6 23.1214 67.7564 0.0
PWD/PhJ m 48.9 23.1214 96.0564 1.7436




  GWAS USING LINEAR MIXED MODELS