Project measure / variable:   Rusyn2   ALT_8_tce

ID, description, units MPD:36118   ALT_8_tce   alanine transaminase (serum ALT), treated group   [IU/L]  8h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   17 strains     sex: m     age: 7wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Rusyn2 - alanine transaminase (serum ALT), treated group 8h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested17 strains
Mean of the strain means66.5   IU/L
Median of the strain means52.0   IU/L
SD of the strain means± 36.4
Coefficient of variation (CV)0.547
Min–max range of strain means27.0   –   156   IU/L
Mean sample size per strain3.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 16 63299.8816 3956.2426 2.8347 0.0052
Residuals 34 47451.36 1395.6282


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 34.5 9.8   3 5.66 0.284 25.3, 44.8 -0.88
A/J m 122.0 49.9   3 28.8 0.41 67.6, 166.0 1.53
AKR/J m 73.5 28.2   3 16.3 0.384 55.0, 106.0 0.19
B6C3F1/J m 27.0 16.3   3 9.43 0.605 9.0, 40.9 -1.09
BALB/cByJ m 82.2 64.9   3 37.4 0.789 41.0, 157.0 0.43
BTBR T+ Itpr3tf/J m 32.9 10.1   3 5.83 0.307 27.0, 44.6 -0.92
C3H/HeJ m 39.5 9.75   3 5.63 0.247 33.2, 50.7 -0.74
C57BL/6J m 33.9 9.09   3 5.25 0.268 26.6, 44.1 -0.9
CAST/EiJ m 52.0 25.6   3 14.8 0.491 33.7, 81.2 -0.4
DBA/2J m 45.1 20.8   3 12.0 0.462 26.8, 67.8 -0.59
FVB/NJ m 93.9 41.5   3 24.0 0.442 53.0, 136.0 0.75
KK/HlJ m 45.8 16.4   3 9.45 0.357 32.5, 64.1 -0.57
MOLF/EiJ m 85.0 47.3   3 27.3 0.556 37.5, 132.0 0.51
NOD/ShiLtJ m 99.4 82.8   3 47.8 0.832 50.5, 195.0 0.91
NZW/LacJ m 35.5 14.0   3 8.09 0.395 26.4, 51.6 -0.85
PWD/PhJ m 71.5 30.7   3 17.7 0.43 36.4, 93.4 0.14
WSB/EiJ m 156.0 47.8   3 27.6 0.307 116.0, 209.0 2.46


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 34.5 21.5687 78.3329 0.0
A/J m 121.5333 21.5687 165.3662 77.7004
AKR/J m 73.5333 21.5687 117.3662 29.7004
B6C3F1/J m 27.0 21.5687 70.8329 0.0
BALB/cByJ m 82.2333 21.5687 126.0662 38.4004
BTBR T+ Itpr3tf/J m 32.9333 21.5687 76.7662 0.0
C3H/HeJ m 39.4667 21.5687 83.2996 0.0
C57BL/6J m 33.9333 21.5687 77.7662 0.0
CAST/EiJ m 52.0 21.5687 95.8329 8.1671
DBA/2J m 45.1333 21.5687 88.9662 1.3004
FVB/NJ m 93.9333 21.5687 137.7662 50.1004
KK/HlJ m 45.8333 21.5687 89.6662 2.0004
MOLF/EiJ m 85.0 21.5687 128.8329 41.1671
NOD/ShiLtJ m 99.4333 21.5687 143.2662 55.6004
NZW/LacJ m 35.4667 21.5687 79.2996 0.0
PWD/PhJ m 71.5333 21.5687 115.3662 27.7004
WSB/EiJ m 156.0 21.5687 199.8329 112.1671




  GWAS USING LINEAR MIXED MODELS