Project measure / variable:   Shockley1   NEFA_fat

ID, description, units MPD:33438   NEFA_fat   nonesterified fatty acid (NEFA)   [mEq/L]  high-fat diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Shockley1 - nonesterified fatty acid (NEFA) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means2.33   mEq/L 2.38   mEq/L
Median of the strain means2.43   mEq/L 2.53   mEq/L
SD of the strain means± 0.703 ± 0.460
Coefficient of variation (CV)0.302 0.193
Min–max range of strain means0.960   –   3.38   mEq/L 1.56   –   3.18   mEq/L
Mean sample size per strain4.8   mice 4.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0093 0.0093 0.0429 0.8366
strain 9 22.1034 2.4559 11.3234 < 0.0001
sex:strain 9 6.0129 0.6681 3.0804 0.0037
Residuals 69 14.9654 0.2169


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.27 0.354   2   0.25 0.156 2.02, 2.52 -0.09
129S1/SvImJ m 2.53 0.457   5 0.204 0.18 1.99, 3.14 0.32
A/J f 2.52 0.118   4 0.0592 0.0469 2.38, 2.67 0.27
A/J m 2.15 0.262   5 0.117 0.122 1.82, 2.47 -0.5
BALB/cJ f 2.76 0.44   5 0.197 0.159 2.03, 3.21 0.61
BALB/cJ m 2.57 0.329   5 0.147 0.128 2.19, 2.99 0.41
C3H/HeJ f 1.88 0.144   5 0.0643 0.0764 1.71, 2.05 -0.64
C3H/HeJ m 2.59 0.735   2   0.52 0.284 2.07, 3.11 0.45
C57BL/6J f 1.62 0.329   5 0.147 0.203 1.14, 2.04 -1.01
C57BL/6J m 1.56 0.0826   5 0.037 0.0528 1.46, 1.69 -1.79
DBA/2J f 3.05 0.883   5 0.395 0.29 2.11, 4.26 1.02
DBA/2J m 3.18 0.683   3 0.394 0.215 2.56, 3.91 1.74
I/LnJ f 0.96 0.183   4 0.0917 0.191 0.77, 1.15 -1.95
I/LnJ m 1.99 0.523   5 0.234 0.263 1.58, 2.84 -0.85
MRL/MpJ-Faslpr/J f 3.38 0.601   5 0.269 0.178 2.66, 4.12 1.49
MRL/MpJ-Faslpr/J m 2.53 0.391   5 0.175 0.155 1.86, 2.86 0.32
NZB/BlNJ f 2.42 0.145   5 0.0647 0.0597 2.3, 2.59 0.13
NZB/BlNJ m 2.0 0.321   4 0.16 0.16 1.6, 2.36 -0.83
SM/J f 2.44 0.794   5 0.355 0.325 1.81, 3.8 0.16
SM/J m 2.72 0.544   5 0.243 0.2 2.15, 3.62 0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.27 0.3293 2.927 1.613
129S1/SvImJ m 2.532 0.2083 2.9475 2.1165
A/J f 2.525 0.2329 2.9895 2.0605
A/J m 2.15 0.2083 2.5655 1.7345
BALB/cJ f 2.762 0.2083 3.1775 2.3465
BALB/cJ m 2.566 0.2083 2.9815 2.1505
C3H/HeJ f 1.88 0.2083 2.2955 1.4645
C3H/HeJ m 2.59 0.3293 3.247 1.933
C57BL/6J f 1.618 0.2083 2.0335 1.2025
C57BL/6J m 1.564 0.2083 1.9795 1.1485
DBA/2J f 3.048 0.2083 3.4635 2.6325
DBA/2J m 3.1767 0.2689 3.7131 2.6403
I/LnJ f 0.96 0.2329 1.4245 0.4955
I/LnJ m 1.988 0.2083 2.4035 1.5725
MRL/MpJ-Faslpr/J f 3.378 0.2083 3.7935 2.9625
MRL/MpJ-Faslpr/J m 2.528 0.2083 2.9435 2.1125
NZB/BlNJ f 2.424 0.2083 2.8395 2.0085
NZB/BlNJ m 2.0025 0.2329 2.467 1.538
SM/J f 2.44 0.2083 2.8555 2.0245
SM/J m 2.722 0.2083 3.1375 2.3065


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.401 0.1948 2.7897 2.0123
A/J both 2.3375 0.1562 2.6491 2.0259
BALB/cJ both 2.664 0.1473 2.9578 2.3702
C3H/HeJ both 2.235 0.1948 2.6237 1.8463
C57BL/6J both 1.591 0.1473 1.8848 1.2972
DBA/2J both 3.1123 0.1701 3.4516 2.7731
I/LnJ both 1.474 0.1562 1.7856 1.1624
MRL/MpJ-Faslpr/J both 2.953 0.1473 3.2468 2.6592
NZB/BlNJ both 2.2133 0.1562 2.5249 1.9016
SM/J both 2.581 0.1473 2.8748 2.2872




  GWAS USING LINEAR MIXED MODELS