Project measure / variable:   Shockley1   TG

ID, description, units MPD:33409   TG   triglycerides (TG, 5h fast)   [mg/dL]  control diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Shockley1 - triglycerides (TG, 5h fast) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means96.0   mg/dL 116   mg/dL
Median of the strain means89.4   mg/dL 103   mg/dL
SD of the strain means± 42.3 ± 57.7
Coefficient of variation (CV)0.441 0.499
Min–max range of strain means57.0   –   192   mg/dL 51.6   –   246   mg/dL
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9488.3889 9488.3889 4.65 0.0341
strain 9 118108.0283 13123.1143 6.4312 < 0.0001
sex:strain 9 111830.9101 12425.6567 6.0894 < 0.0001
Residuals 79 161201.4 2040.5241


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 192.0 141.0   5 63.0 0.733 52.0, 364.0 2.27
129S1/SvImJ m 76.2 31.8   5 14.2 0.418 47.0, 122.0 -0.68
A/J f 92.0 23.7   5 10.6 0.258 69.0, 122.0 -0.09
A/J m 105.0 21.1   5 9.45 0.202 87.0, 135.0 -0.18
BALB/cJ f 62.6 10.1   5 4.5 0.161 49.0, 74.0 -0.79
BALB/cJ m 51.6 6.43   5 2.87 0.125 48.0, 63.0 -1.11
C3H/HeJ f 60.8 9.39   5 4.2 0.154 51.0, 75.0 -0.83
C3H/HeJ m 90.8 13.8   5 6.18 0.152 68.0, 104.0 -0.43
C57BL/6J f 66.4 9.61   5 4.3 0.145 54.0, 76.0 -0.7
C57BL/6J m 65.6 3.51   5 1.57 0.0535 60.0, 69.0 -0.87
DBA/2J f 86.8 15.9   5 7.1 0.183 67.0, 104.0 -0.22
DBA/2J m 246.0 103.0   5 46.2 0.42 140.0, 411.0 2.26
I/LnJ f 99.5 14.3   4 7.14 0.143 83.0, 117.0 0.08
I/LnJ m 101.0 33.5   5 15.0 0.332 67.0, 143.0 -0.25
MRL/MpJ-Faslpr/J f 141.0 46.1   5 20.6 0.327 71.0, 186.0 1.06
MRL/MpJ-Faslpr/J m 130.0 28.3   5 12.6 0.217 100.0, 166.0 0.25
NZB/BlNJ f 57.0 11.2   5 5.03 0.197 45.0, 75.0 -0.92
NZB/BlNJ m 114.0 26.3   5 11.7 0.231 77.0, 149.0 -0.03
SM/J f 102.0 29.6   5 13.3 0.289 74.0, 145.0 0.14
SM/J m 176.0 33.5   5 15.0 0.191 138.0, 230.0 1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 192.0 20.2016 232.2103 151.7897
129S1/SvImJ m 76.2 20.2016 116.4103 35.9897
A/J f 92.0 20.2016 132.2103 51.7897
A/J m 104.8 20.2016 145.0103 64.5897
BALB/cJ f 62.6 20.2016 102.8103 22.3897
BALB/cJ m 51.6 20.2016 91.8103 11.3897
C3H/HeJ f 60.8 20.2016 101.0103 20.5897
C3H/HeJ m 90.8 20.2016 131.0103 50.5897
C57BL/6J f 66.4 20.2016 106.6103 26.1897
C57BL/6J m 65.6 20.2016 105.8103 25.3897
DBA/2J f 86.8 20.2016 127.0103 46.5897
DBA/2J m 245.8 20.2016 286.0103 205.5897
I/LnJ f 99.5 22.5861 144.4565 54.5435
I/LnJ m 101.0 20.2016 141.2103 60.7897
MRL/MpJ-Faslpr/J f 140.8 20.2016 181.0103 100.5897
MRL/MpJ-Faslpr/J m 130.2 20.2016 170.4103 89.9897
NZB/BlNJ f 57.0 20.2016 97.2103 16.7897
NZB/BlNJ m 113.8 20.2016 154.0103 73.5897
SM/J f 102.4 20.2016 142.6103 62.1897
SM/J m 175.6 20.2016 215.8103 135.3897


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 134.1 14.2847 162.533 105.667
A/J both 98.4 14.2847 126.833 69.967
BALB/cJ both 57.1 14.2847 85.533 28.667
C3H/HeJ both 75.8 14.2847 104.233 47.367
C57BL/6J both 66.0 14.2847 94.433 37.567
DBA/2J both 166.3 14.2847 194.733 137.867
I/LnJ both 100.25 15.1512 130.4077 70.0923
MRL/MpJ-Faslpr/J both 135.5 14.2847 163.933 107.067
NZB/BlNJ both 85.4 14.2847 113.833 56.967
SM/J both 139.0 14.2847 167.433 110.567




  GWAS USING LINEAR MIXED MODELS