Project measure / variable:   Shockley1   NEFA

ID, description, units MPD:33408   NEFA   nonesterified fatty acid (NEFA)   [mEq/L]  control diet  
high-fat diet study
Data set, strains Shockley1   inbred   10 strains     sex: both     age: 10-13wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Shockley1 - nonesterified fatty acid (NEFA) control diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means2.58   mEq/L 2.86   mEq/L
Median of the strain means2.37   mEq/L 2.63   mEq/L
SD of the strain means± 0.623 ± 0.876
Coefficient of variation (CV)0.241 0.306
Min–max range of strain means2.06   –   3.92   mEq/L 1.96   –   4.61   mEq/L
Mean sample size per strain5.0   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.9359 1.9359 8.1213 0.0056
strain 9 46.6149 5.1794 21.7282 < 0.0001
sex:strain 9 5.0758 0.564 2.3659 0.0201
Residuals 79 18.8315 0.2384


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.36 0.442   5 0.198 0.187 1.98, 3.1 -0.35
129S1/SvImJ m 2.63 0.449   5 0.201 0.171 2.29, 3.39 -0.27
A/J f 2.44 0.358   5 0.16 0.147 1.99, 2.89 -0.22
A/J m 2.64 0.524   5 0.234 0.198 2.14, 3.4 -0.26
BALB/cJ f 2.15 0.168   5 0.075 0.0779 1.86, 2.27 -0.69
BALB/cJ m 2.03 0.258   5 0.116 0.127 1.7, 2.41 -0.95
C3H/HeJ f 2.24 0.191   5 0.0856 0.0853 2.02, 2.47 -0.54
C3H/HeJ m 2.37 0.374   5 0.167 0.158 1.84, 2.72 -0.57
C57BL/6J f 2.06 0.185   5 0.0826 0.0896 1.86, 2.29 -0.83
C57BL/6J m 2.1 0.203   5 0.0908 0.0967 1.92, 2.41 -0.87
DBA/2J f 2.43 0.409   5 0.183 0.168 1.99, 3.03 -0.24
DBA/2J m 2.97 0.263   5 0.118 0.0884 2.7, 3.33 0.12
I/LnJ f 2.29 0.876   4 0.438 0.382 1.5, 3.34 -0.46
I/LnJ m 1.96 0.369   5 0.165 0.189 1.37, 2.33 -1.03
MRL/MpJ-Faslpr/J f 3.92 0.981   5 0.439 0.25 2.46, 4.99 2.15
MRL/MpJ-Faslpr/J m 3.89 0.512   5 0.229 0.132 3.43, 4.67 1.17
NZB/BlNJ f 2.37 0.289   5 0.129 0.122 2.18, 2.88 -0.34
NZB/BlNJ m 3.45 0.508   5 0.227 0.147 2.85, 3.94 0.67
SM/J f 3.53 0.743   5 0.332 0.211 2.9, 4.8 1.53
SM/J m 4.61 0.703   5 0.314 0.152 3.83, 5.34 1.99


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.364 0.2183 2.7986 1.9294
129S1/SvImJ m 2.628 0.2183 3.0626 2.1934
A/J f 2.438 0.2183 2.8726 2.0034
A/J m 2.642 0.2183 3.0766 2.2074
BALB/cJ f 2.152 0.2183 2.5866 1.7174
BALB/cJ m 2.03 0.2183 2.4646 1.5954
C3H/HeJ f 2.244 0.2183 2.6786 1.8094
C3H/HeJ m 2.374 0.2183 2.8086 1.9394
C57BL/6J f 2.062 0.2183 2.4966 1.6274
C57BL/6J m 2.1 0.2183 2.5346 1.6654
DBA/2J f 2.43 0.2183 2.8646 1.9954
DBA/2J m 2.974 0.2183 3.4086 2.5394
I/LnJ f 2.29 0.2441 2.7759 1.8041
I/LnJ m 1.958 0.2183 2.3926 1.5234
MRL/MpJ-Faslpr/J f 3.918 0.2183 4.3526 3.4834
MRL/MpJ-Faslpr/J m 3.886 0.2183 4.3206 3.4514
NZB/BlNJ f 2.372 0.2183 2.8066 1.9374
NZB/BlNJ m 3.452 0.2183 3.8866 3.0174
SM/J f 3.526 0.2183 3.9606 3.0914
SM/J m 4.608 0.2183 5.0426 4.1734


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.496 0.1544 2.8033 2.1887
A/J both 2.54 0.1544 2.8473 2.2327
BALB/cJ both 2.091 0.1544 2.3983 1.7837
C3H/HeJ both 2.309 0.1544 2.6163 2.0017
C57BL/6J both 2.081 0.1544 2.3883 1.7737
DBA/2J both 2.702 0.1544 3.0093 2.3947
I/LnJ both 2.124 0.1638 2.45 1.798
MRL/MpJ-Faslpr/J both 3.902 0.1544 4.2093 3.5947
NZB/BlNJ both 2.912 0.1544 3.2193 2.6047
SM/J both 4.067 0.1544 4.3743 3.7597




  GWAS USING LINEAR MIXED MODELS