Project measure / variable:   Yuan3   Na_M18

ID, description, units MPD:24448   Na_M18   sodium (serum Na)   [mmol/L]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
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  STRAIN COMPARISON PLOT
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Yuan3 - sodium (serum Na) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means157   mmol/L 158   mmol/L
Median of the strain means156   mmol/L 157   mmol/L
SD of the strain means± 4.77 ± 5.59
Coefficient of variation (CV)0.0304 0.0355
Min–max range of strain means148   –   169   mmol/L 146   –   170   mmol/L
Mean sample size per strain7.1   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 34.4154 34.4154 1.8842 0.1708
strain 26 6579.0585 253.0407 13.8535 < 0.0001
sex:strain 26 2780.6546 106.9483 5.8552 < 0.0001
Residuals 314 5735.3389 18.2654


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 163.0 3.5   7 1.32 0.0215 158.0, 169.0 1.34
129S1/SvImJ m 160.0 3.73   8 1.32 0.0233 152.0, 165.0 0.44
A/J f 163.0 4.04   8 1.43 0.0248 158.0, 168.0 1.34
A/J m 170.0 2.56   6 1.05 0.0151 166.0, 173.0 2.23
BALB/cByJ f 157.0 3.09   7 1.17 0.0197 152.0, 160.0 0.08
BALB/cByJ m 164.0 2.56   6 1.05 0.0156 160.0, 168.0 1.16
BTBR T+ Itpr3tf/J f 151.0 2.23   6 0.91 0.0147 149.0, 155.0 -1.18
BTBR T+ Itpr3tf/J m 153.0 1.67   5 0.748 0.011 150.0, 154.0 -0.81
BUB/BnJ f 155.0 3.29   5 1.47 0.0213 151.0, 158.0 -0.34
C3H/HeJ f 154.0 2.42   6 0.989 0.0158 151.0, 157.0 -0.55
C3H/HeJ m 156.0 2.43   8 0.861 0.0156 153.0, 160.0 -0.27
C57BL/10J f 155.0 4.56   7 1.72 0.0294 148.0, 160.0 -0.34
C57BL/10J m 163.0 2.29   7 0.865 0.014 160.0, 167.0 0.98
C57BL/6J f 151.0 2.0   8 0.706 0.0132 150.0, 156.0 -1.18
C57BL/6J m 154.0 2.12   7 0.8 0.0138 152.0, 158.0 -0.63
C57BLKS/J f 154.0 2.87   7 1.08 0.0187 150.0, 157.0 -0.55
C57BLKS/J m 161.0 2.47   8 0.875 0.0154 158.0, 164.0 0.62
C57BR/cdJ f 156.0 1.77   8 0.627 0.0114 152.0, 158.0 -0.13
C57BR/cdJ m 158.0 2.0   8 0.706 0.0127 154.0, 159.0 0.08
C57L/J f 165.0 4.95   8 1.75 0.03 156.0, 174.0 1.76
C57L/J m 155.0 2.53   6 1.03 0.0163 152.0, 158.0 -0.45
CBA/J f 154.0 2.47   8 0.875 0.0161 150.0, 157.0 -0.55
CBA/J m 154.0 2.58   6 1.05 0.0167 152.0, 159.0 -0.63
DBA/2J f 153.0 0.894   5 0.4 0.00586 152.0, 154.0 -0.76
DBA/2J m 158.0 3.7   8 1.31 0.0235 152.0, 163.0 0.08
FVB/NJ f 154.0 1.77   8 0.625 0.0115 152.0, 158.0 -0.55
FVB/NJ m 162.0 1.58   5 0.707 0.00976 160.0, 164.0 0.8
KK/HlJ f 153.0 10.7   9 3.58 0.0701 137.0, 169.0 -0.76
KK/HlJ m 156.0 5.74   7 2.17 0.0369 148.0, 163.0 -0.27
LP/J f 152.0 3.95   7 1.49 0.0259 145.0, 156.0 -0.97
LP/J m 152.0 3.52   8 1.25 0.0232 144.0, 156.0 -0.99
MRL/MpJ f 156.0 9.19   2   6.5 0.0587 150.0, 163.0 -0.13
MRL/MpJ m 158.0 4.49   5 2.01 0.0284 155.0, 166.0 0.08
NOD.B10Sn-H2b/J f 159.0 4.31   7 1.63 0.0271 154.0, 165.0 0.5
NOD.B10Sn-H2b/J m 156.0 2.22   4 1.11 0.0142 154.0, 159.0 -0.27
NON/ShiLtJ f 163.0 8.15   14 2.18 0.0501 154.0, 178.0 1.34
NON/ShiLtJ m 154.0 7.24   7 2.74 0.047 138.0, 158.0 -0.63
NZO/HlLtJ f 157.0 12.5   9 4.18 0.0801 137.0, 170.0 0.08
NZO/HlLtJ m 161.0 0.0   1   0.0 0.0 161.0, 161.0 0.62
NZW/LacJ f 156.0 5.59   5 2.5 0.0359 148.0, 162.0 -0.13
NZW/LacJ m 155.0 2.58   7 0.976 0.0167 151.0, 158.0 -0.45
P/J f 162.0 1.87   5 0.837 0.0115 159.0, 164.0 1.13
P/J m 146.0 3.3   4 1.65 0.0226 143.0, 150.0 -2.06
PL/J f 148.0 6.97   7 2.64 0.047 139.0, 158.0 -1.81
PL/J m 146.0 0.577   4 0.289 0.00397 145.0, 146.0 -2.06
PWD/PhJ f 154.0 1.51   7 0.571 0.00984 152.0, 156.0 -0.55
PWD/PhJ m 159.0 4.45   8 1.57 0.028 154.0, 166.0 0.26
RIIIS/J f 160.0 4.24   8 1.5 0.0265 155.0, 167.0 0.71
RIIIS/J m 156.0 2.71   8 0.959 0.0174 152.0, 160.0 -0.27
SJL/J f 159.0 5.54   8 1.96 0.0349 151.0, 166.0 0.5
SJL/J m 154.0 2.34   6 0.955 0.0151 152.0, 157.0 -0.63
SM/J f 156.0 2.08   7 0.787 0.0133 154.0, 160.0 -0.13
SM/J m 162.0 1.14   5 0.51 0.00706 160.0, 163.0 0.8
SWR/J f 153.0 7.34   8 2.6 0.0479 143.0, 162.0 -0.76
SWR/J m 158.0 4.55   6 1.86 0.0287 152.0, 166.0 0.08
WSB/EiJ f 169.0 3.14   8 1.11 0.0185 166.0, 176.0 2.6
WSB/EiJ m 170.0 2.34   6 0.955 0.0138 166.0, 172.0 2.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 162.7143 1.6153 165.8926 159.536
129S1/SvImJ m 160.25 1.511 163.223 157.277
A/J f 163.0 1.511 165.973 160.027
A/J m 169.8333 1.7448 173.2663 166.4004
BALB/cByJ f 157.2857 1.6153 160.464 154.1074
BALB/cByJ m 164.1667 1.7448 167.5996 160.7337
BTBR T+ Itpr3tf/J f 151.1667 1.7448 154.5996 147.7337
BTBR T+ Itpr3tf/J m 152.6 1.9113 156.3606 148.8394
C3H/HeJ f 153.6667 1.7448 157.0996 150.2337
C3H/HeJ m 156.25 1.511 159.223 153.277
C57BL/10J f 155.1429 1.6153 158.3211 151.9646
C57BL/10J m 163.2857 1.6153 166.464 160.1074
C57BL/6J f 151.375 1.511 154.348 148.402
C57BL/6J m 153.8571 1.6153 157.0354 150.6789
C57BLKS/J f 153.7143 1.6153 156.8926 150.536
C57BLKS/J m 160.875 1.511 163.848 157.902
C57BR/cdJ f 155.5 1.511 158.473 152.527
C57BR/cdJ m 157.625 1.511 160.598 154.652
C57L/J f 164.75 1.511 167.723 161.777
C57L/J m 155.0 1.7448 158.4329 151.5671
CBA/J f 153.875 1.511 156.848 150.902
CBA/J m 154.3333 1.7448 157.7663 150.9004
DBA/2J f 152.6 1.9113 156.3606 148.8394
DBA/2J m 157.625 1.511 160.598 154.652
FVB/NJ f 154.375 1.511 157.348 151.402
FVB/NJ m 162.0 1.9113 165.7606 158.2394
KK/HlJ f 153.2222 1.4246 156.0252 150.4193
KK/HlJ m 155.5714 1.6153 158.7497 152.3932
LP/J f 152.2857 1.6153 155.464 149.1074
LP/J m 151.875 1.511 154.848 148.902
MRL/MpJ f 156.5 3.022 162.446 150.554
MRL/MpJ m 158.2 1.9113 161.9606 154.4394
NOD.B10Sn-H2b/J f 159.2857 1.6153 162.464 156.1074
NOD.B10Sn-H2b/J m 156.25 2.1369 160.4545 152.0455
NON/ShiLtJ f 162.8571 1.1422 165.1045 160.6098
NON/ShiLtJ m 154.1429 1.6153 157.3211 150.9646
NZW/LacJ f 155.8 1.9113 159.5606 152.0394
NZW/LacJ m 155.0 1.6153 158.1783 151.8217
P/J f 162.0 1.9113 165.7606 158.2394
P/J m 146.25 2.1369 150.4545 142.0455
PL/J f 148.4286 1.6153 151.6068 145.2503
PL/J m 145.5 2.1369 149.7045 141.2955
PWD/PhJ f 153.5714 1.6153 156.7497 150.3932
PWD/PhJ m 159.125 1.511 162.098 156.152
RIIIS/J f 160.0 1.511 162.973 157.027
RIIIS/J m 155.75 1.511 158.723 152.777
SJL/J f 158.875 1.511 161.848 155.902
SJL/J m 154.3333 1.7448 157.7663 150.9004
SM/J f 156.0 1.6153 159.1783 152.8217
SM/J m 161.6 1.9113 165.3606 157.8394
SWR/J f 153.25 1.511 156.223 150.277
SWR/J m 158.5 1.7448 161.9329 155.0671
WSB/EiJ f 169.125 1.511 172.098 166.152
WSB/EiJ m 169.6667 1.7448 173.0996 166.2337


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 161.4821 1.106 163.6582 159.3061
A/J both 166.4167 1.1541 168.6873 164.146
BALB/cByJ both 160.7262 1.1889 163.0653 158.387
BTBR T+ Itpr3tf/J both 151.8833 1.294 154.4293 149.3374
C3H/HeJ both 154.9583 1.1541 157.229 152.6877
C57BL/10J both 159.2143 1.1422 161.4617 156.9669
C57BL/6J both 152.6161 1.106 154.7921 150.4401
C57BLKS/J both 157.2946 1.106 159.4707 155.1186
C57BR/cdJ both 156.5625 1.0685 158.6647 154.4603
C57L/J both 159.875 1.1541 162.1457 157.6043
CBA/J both 154.1042 1.1541 156.3748 151.8335
DBA/2J both 155.1125 1.2182 157.5094 152.7156
FVB/NJ both 158.1875 1.2182 160.5844 155.7906
KK/HlJ both 154.3968 1.0769 156.5157 152.278
LP/J both 152.0804 1.106 154.2564 149.9043
MRL/MpJ both 157.35 1.7879 160.8677 153.8323
NOD.B10Sn-H2b/J both 157.7679 1.3394 160.4031 155.1326
NON/ShiLtJ both 158.5 0.9892 160.4463 156.5537
NZW/LacJ both 155.4 1.2512 157.8619 152.9381
P/J both 154.125 1.4335 156.9454 151.3046
PL/J both 146.9643 1.3394 149.5996 144.329
PWD/PhJ both 156.3482 1.106 158.5242 154.1722
RIIIS/J both 157.875 1.0685 159.9772 155.7728
SJL/J both 156.6042 1.1541 158.8748 154.3335
SM/J both 158.8 1.2512 161.2619 156.3381
SWR/J both 155.875 1.1541 158.1457 153.6043
WSB/EiJ both 169.3958 1.1541 171.6665 167.1252




  GWAS USING LINEAR MIXED MODELS