Project measure / variable:   Yuan3   Fe_M18

ID, description, units MPD:24428   Fe_M18   iron (serum Fe)   [mmol/L]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - iron (serum Fe) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means225   mmol/L 206   mmol/L
Median of the strain means209   mmol/L 203   mmol/L
SD of the strain means± 54.3 ± 45.9
Coefficient of variation (CV)0.241 0.222
Min–max range of strain means130   –   354   mmol/L 135   –   359   mmol/L
Mean sample size per strain7.1   mice 5.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21769.2722 21769.2722 13.1132 0.0003
strain 26 672793.3138 25876.6659 15.5874 < 0.0001
sex:strain 26 133676.9642 5141.4217 3.0971 < 0.0001
Residuals 297 493049.8857 1660.1006


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 208.0 53.1   7 20.1 0.255 137.0, 303.0 -0.32
129S1/SvImJ m 218.0 37.5   7 14.2 0.172 167.0, 270.0 0.25
A/J f 224.0 15.3   7 5.79 0.0685 206.0, 245.0 -0.02
A/J m 250.0 11.6   5 5.17 0.0463 239.0, 263.0 0.95
BALB/cByJ f 188.0 20.4   7 7.69 0.108 153.0, 212.0 -0.69
BALB/cByJ m 194.0 31.1   5 13.9 0.16 168.0, 242.0 -0.27
BTBR T+ Itpr3tf/J f 279.0 104.0   6 42.6 0.374 166.0, 441.0 0.99
BTBR T+ Itpr3tf/J m 219.0 11.6   5 5.2 0.053 203.0, 230.0 0.27
BUB/BnJ f 311.0 31.5   5 14.1 0.101 268.0, 338.0 1.58
C3H/HeJ f 186.0 64.0   6 26.1 0.343 77.0, 276.0 -0.72
C3H/HeJ m 205.0 38.8   8 13.7 0.189 122.0, 239.0 -0.03
C57BL/10J f 130.0 23.7   7 8.95 0.182 101.0, 172.0 -1.75
C57BL/10J m 155.0 29.7   7 11.2 0.191 108.0, 190.0 -1.12
C57BL/6J f 166.0 25.5   8 9.01 0.153 135.0, 207.0 -1.09
C57BL/6J m 158.0 27.0   6 11.0 0.171 117.0, 194.0 -1.06
C57BLKS/J f 135.0 14.3   7 5.39 0.106 120.0, 163.0 -1.66
C57BLKS/J m 161.0 14.6   7 5.51 0.0903 143.0, 189.0 -0.99
C57BR/cdJ f 227.0 40.3   8 14.2 0.177 173.0, 281.0 0.03
C57BR/cdJ m 183.0 63.9   8 22.6 0.349 67.0, 259.0 -0.51
C57L/J f 223.0 42.7   8 15.1 0.192 184.0, 322.0 -0.04
C57L/J m 201.0 2.83   2   2.0 0.0141 199.0, 203.0 -0.12
CBA/J f 215.0 18.1   8 6.41 0.0842 194.0, 241.0 -0.19
CBA/J m 222.0 20.6   3 11.9 0.0927 202.0, 243.0 0.34
DBA/2J f 162.0 15.7   5 7.0 0.0964 142.0, 184.0 -1.16
DBA/2J m 178.0 23.1   8 8.16 0.13 155.0, 215.0 -0.62
FVB/NJ f 354.0 49.3   8 17.4 0.139 290.0, 428.0 2.37
FVB/NJ m 224.0 41.8   4 20.9 0.187 191.0, 278.0 0.38
KK/HlJ f 208.0 58.6   10 18.5 0.282 126.0, 296.0 -0.32
KK/HlJ m 196.0 29.1   7 11.0 0.148 145.0, 223.0 -0.23
LP/J f 230.0 52.8   7 20.0 0.23 169.0, 318.0 0.09
LP/J m 243.0 21.6   8 7.63 0.0887 212.0, 285.0 0.8
MRL/MpJ f 265.0 99.0   2   70.0 0.374 195.0, 335.0 0.73
MRL/MpJ m 359.0 63.0   5 28.2 0.175 274.0, 426.0 3.33
NOD.B10Sn-H2b/J f 209.0 68.6   7 25.9 0.328 109.0, 340.0 -0.3
NOD.B10Sn-H2b/J m 191.0 24.2   4 12.1 0.127 161.0, 216.0 -0.34
NON/ShiLtJ f 204.0 37.7   14 10.1 0.185 134.0, 268.0 -0.39
NON/ShiLtJ m 178.0 14.3   7 5.4 0.08 149.0, 193.0 -0.62
NZO/HlLtJ f 175.0 29.4   9 9.78 0.168 128.0, 233.0 -0.92
NZO/HlLtJ m 135.0 0.0   1   0.0 0.0 135.0, 135.0 -1.56
NZW/LacJ f 199.0 26.8   5 12.0 0.135 169.0, 242.0 -0.48
NZW/LacJ m 224.0 31.9   7 12.1 0.142 177.0, 259.0 0.38
P/J f 288.0 57.4   5 25.7 0.199 240.0, 375.0 1.16
P/J m 216.0 14.4   4 7.19 0.0668 194.0, 224.0 0.21
PL/J f 200.0 27.5   7 10.4 0.137 159.0, 231.0 -0.46
PL/J m 205.0 23.4   4 11.7 0.114 177.0, 231.0 -0.03
PWD/PhJ f 207.0 30.7   7 11.6 0.149 166.0, 246.0 -0.34
PWD/PhJ m 158.0 16.1   4 8.07 0.102 144.0, 177.0 -1.06
RIIIS/J f 252.0 69.3   7 26.2 0.275 129.0, 361.0 0.49
RIIIS/J m 181.0 20.9   8 7.39 0.116 160.0, 211.0 -0.56
SJL/J f 199.0 32.3   8 11.4 0.163 159.0, 246.0 -0.48
SJL/J m 171.0 5.98   6 2.44 0.0349 161.0, 178.0 -0.77
SM/J f 278.0 38.6   7 14.6 0.139 221.0, 335.0 0.97
SM/J m 219.0 59.3   5 26.5 0.271 163.0, 299.0 0.27
SWR/J f 313.0 66.0   8 23.4 0.211 216.0, 410.0 1.62
SWR/J m 300.0 28.8   6 11.8 0.0961 264.0, 345.0 2.04
WSB/EiJ f 297.0 17.0   8 5.99 0.0571 277.0, 330.0 1.32
WSB/EiJ m 238.0 29.8   7 11.3 0.125 202.0, 297.0 0.69


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 208.1429 15.3999 238.4496 177.8361
129S1/SvImJ m 218.1429 15.3999 248.4496 187.8361
A/J f 223.8571 15.3999 254.1639 193.5504
A/J m 249.6 18.2214 285.4595 213.7405
BALB/cByJ f 188.4286 15.3999 218.7353 158.1218
BALB/cByJ m 194.2 18.2214 230.0595 158.3405
BTBR T+ Itpr3tf/J f 279.1667 16.6338 311.9017 246.4316
BTBR T+ Itpr3tf/J m 219.2 18.2214 255.0595 183.3405
C3H/HeJ f 186.5 16.6338 219.2351 153.7649
C3H/HeJ m 205.125 14.4053 233.4744 176.7756
C57BL/10J f 130.0 15.3999 160.3068 99.6932
C57BL/10J m 155.2857 15.3999 185.5925 124.9789
C57BL/6J f 166.5 14.4053 194.8494 138.1506
C57BL/6J m 158.1667 16.6338 190.9017 125.4316
C57BLKS/J f 134.8571 15.3999 165.1639 104.5504
C57BLKS/J m 161.2857 15.3999 191.5925 130.9789
C57BR/cdJ f 227.25 14.4053 255.5994 198.9006
C57BR/cdJ m 183.125 14.4053 211.4744 154.7756
C57L/J f 222.625 14.4053 250.9744 194.2756
C57L/J m 201.0 28.8106 257.6988 144.3012
CBA/J f 215.375 14.4053 243.7244 187.0256
CBA/J m 221.6667 23.5238 267.961 175.3723
DBA/2J f 162.4 18.2214 198.2595 126.5405
DBA/2J m 178.125 14.4053 206.4744 149.7756
FVB/NJ f 354.375 14.4053 382.7244 326.0256
FVB/NJ m 224.0 20.3722 264.0921 183.9079
KK/HlJ f 208.0 12.8845 233.3565 182.6435
KK/HlJ m 196.0 15.3999 226.3068 165.6932
LP/J f 229.5714 15.3999 259.8782 199.2647
LP/J m 243.25 14.4053 271.5994 214.9006
MRL/MpJ f 265.0 28.8106 321.6988 208.3012
MRL/MpJ m 359.2 18.2214 395.0595 323.3405
NOD.B10Sn-H2b/J f 208.8571 15.3999 239.1639 178.5504
NOD.B10Sn-H2b/J m 191.0 20.3722 231.0921 150.9079
NON/ShiLtJ f 204.4286 10.8894 225.8587 182.9984
NON/ShiLtJ m 178.4286 15.3999 208.7353 148.1218
NZW/LacJ f 199.2 18.2214 235.0595 163.3405
NZW/LacJ m 224.0 15.3999 254.3068 193.6932
P/J f 288.0 18.2214 323.8595 252.1405
P/J m 215.5 20.3722 255.5921 175.4079
PL/J f 200.4286 15.3999 230.7353 170.1218
PL/J m 204.75 20.3722 244.8421 164.6579
PWD/PhJ f 206.7143 15.3999 237.0211 176.4075
PWD/PhJ m 158.5 20.3722 198.5921 118.4079
RIIIS/J f 252.1429 15.3999 282.4496 221.8361
RIIIS/J m 181.0 14.4053 209.3494 152.6506
SJL/J f 198.75 14.4053 227.0994 170.4006
SJL/J m 171.1667 16.6338 203.9017 138.4316
SM/J f 277.8571 15.3999 308.1639 247.5504
SM/J m 219.0 18.2214 254.8595 183.1405
SWR/J f 312.75 14.4053 341.0994 284.4006
SWR/J m 300.1667 16.6338 332.9017 267.4316
WSB/EiJ f 296.75 14.4053 325.0994 268.4006
WSB/EiJ m 238.4286 15.3999 268.7353 208.1218


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 213.1429 10.8894 234.573 191.7127
A/J both 236.7286 11.9287 260.2041 213.253
BALB/cByJ both 191.3143 11.9287 214.7898 167.8388
BTBR T+ Itpr3tf/J both 249.1833 12.336 273.4603 224.9064
C3H/HeJ both 195.8125 11.0022 217.4647 174.1603
C57BL/10J both 142.6429 10.8894 164.073 121.2127
C57BL/6J both 162.3333 11.0022 183.9855 140.6811
C57BLKS/J both 148.0714 10.8894 169.5016 126.6413
C57BR/cdJ both 205.1875 10.1861 225.2335 185.1415
C57L/J both 211.8125 16.1056 243.5081 180.1169
CBA/J both 218.5208 13.792 245.6633 191.3784
DBA/2J both 170.2625 11.6139 193.1185 147.4065
FVB/NJ both 289.1875 12.4754 313.7388 264.6362
KK/HlJ both 202.0 10.0395 221.7576 182.2424
LP/J both 236.4107 10.5436 257.1603 215.6611
MRL/MpJ both 312.1 17.0446 345.6434 278.5566
NOD.B10Sn-H2b/J both 199.9286 12.7689 225.0576 174.7995
NON/ShiLtJ both 191.4286 9.4305 209.9876 172.8695
NZW/LacJ both 211.6 11.9287 235.0755 188.1245
P/J both 251.75 13.6661 278.6446 224.8554
PL/J both 202.5893 12.7689 227.7183 177.4602
PWD/PhJ both 182.6071 12.7689 207.7362 157.4781
RIIIS/J both 216.5714 10.5436 237.3211 195.8218
SJL/J both 184.9583 11.0022 206.6105 163.3061
SM/J both 248.4286 11.9287 271.9041 224.953
SWR/J both 306.4583 11.0022 328.1105 284.8061
WSB/EiJ both 267.5893 10.5436 288.3389 246.8397




  GWAS USING LINEAR MIXED MODELS