Phenotype measure:   Yuan3   Cl_M12

ID, description, units MPD:24422   Cl_M12   chloride (serum Cl)   [mmol/L]  at age 12mo
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - chloride (serum Cl) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means116   mmol/L 116   mmol/L
Median of the strain means116   mmol/L 115   mmol/L
SD of the strain means± 3.69 ± 3.51
Coefficient of variation (CV)0.0317 0.0303
Min–max range of strain means111   –   124   mmol/L 110   –   122   mmol/L
Mean sample size per strain7.3   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 107.6049 107.6049 7.0256 0.0084
strain 28 4042.2848 144.3673 9.4259 < 0.0001
sex:strain 28 1215.9553 43.427 2.8354 < 0.0001
Residuals 367 5620.9927 15.3161


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 113.0 3.55   8 1.25 0.0314 107.0, 119.0 -0.94
129S1/SvImJ m 110.0 3.02   8 1.07 0.0276 103.0, 112.0 -1.65
A/J f 116.0 2.23   6 0.91 0.0192 113.0, 119.0 -0.12
A/J m 120.0 4.05   16 1.01 0.0338 114.0, 127.0 1.2
AKR/J f 111.0 0.0   2   0.0 0.0 111.0, 111.0 -1.48
AKR/J m 112.0 3.21   3 1.86 0.0286 110.0, 116.0 -1.08
BALB/cByJ f 116.0 2.19   8 0.773 0.0188 114.0, 120.0 -0.12
BALB/cByJ m 114.0 3.51   8 1.24 0.0306 107.0, 118.0 -0.51
BTBR T+ Itpr3tf/J f 119.0 2.75   8 0.972 0.0231 114.0, 122.0 0.69
BTBR T+ Itpr3tf/J m 120.0 3.36   7 1.27 0.0281 113.0, 124.0 1.2
BUB/BnJ f 124.0 4.17   6 1.7 0.0337 116.0, 127.0 2.05
BUB/BnJ m 115.0 3.78   9 1.26 0.033 110.0, 122.0 -0.23
C3H/HeJ f 114.0 1.64   8 0.581 0.0144 112.0, 116.0 -0.67
C3H/HeJ m 117.0 2.19   7 0.829 0.0188 114.0, 120.0 0.34
C57BL/10J f 114.0 1.85   8 0.655 0.0162 111.0, 117.0 -0.67
C57BL/10J m 122.0 4.31   7 1.63 0.0352 115.0, 128.0 1.77
C57BL/6J f 114.0 2.31   8 0.818 0.0203 111.0, 118.0 -0.67
C57BL/6J m 112.0 2.51   8 0.886 0.0224 109.0, 117.0 -1.08
C57BLKS/J f 123.0 4.46   8 1.58 0.0364 116.0, 128.0 1.78
C57BLKS/J m 121.0 4.78   8 1.69 0.0396 117.0, 132.0 1.48
C57BR/cdJ f 122.0 3.85   8 1.36 0.0317 114.0, 126.0 1.51
C57BR/cdJ m 120.0 4.54   8 1.6 0.038 115.0, 127.0 1.2
C57L/J f 121.0 4.75   7 1.8 0.0394 114.0, 128.0 1.23
C57L/J m 118.0 5.4   8 1.91 0.0459 111.0, 125.0 0.63
CAST/EiJ f 114.0 3.34   8 1.18 0.0292 108.0, 119.0 -0.67
CBA/J f 116.0 3.63   7 1.37 0.0312 113.0, 124.0 -0.12
CBA/J m 113.0 2.34   6 0.955 0.0206 110.0, 116.0 -0.8
DBA/2J f 115.0 5.78   6 2.36 0.0502 109.0, 126.0 -0.39
DBA/2J m 118.0 3.95   7 1.49 0.0335 112.0, 125.0 0.63
FVB/NJ f 119.0 4.63   8 1.64 0.0388 114.0, 127.0 0.69
FVB/NJ m 117.0 3.06   8 1.08 0.0261 113.0, 123.0 0.34
KK/HlJ f 114.0 4.14   8 1.46 0.0362 108.0, 120.0 -0.67
KK/HlJ m 115.0 3.81   8 1.35 0.0331 111.0, 123.0 -0.23
LP/J f 112.0 1.51   7 0.571 0.0134 111.0, 115.0 -1.21
LP/J m 114.0 2.6   8 0.921 0.0228 112.0, 118.0 -0.51
MRL/MpJ f 117.0 1.92   8 0.68 0.0164 113.0, 119.0 0.15
MRL/MpJ m 119.0 4.95   8 1.75 0.0415 113.0, 128.0 0.91
NOD.B10Sn-H2b/J f 114.0 1.79   6 0.73 0.0157 111.0, 116.0 -0.67
NOD.B10Sn-H2b/J m 112.0 3.66   8 1.3 0.0329 106.0, 116.0 -1.08
NON/ShiLtJ f 120.0 4.67   8 1.65 0.039 114.0, 126.0 0.96
NON/ShiLtJ m 115.0 6.84   7 2.59 0.0596 104.0, 120.0 -0.23
NZO/HlLtJ f 116.0 3.63   7 1.37 0.0312 109.0, 120.0 -0.12
NZO/HlLtJ m 119.0 3.49   6 1.42 0.0294 113.0, 123.0 0.91
NZW/LacJ f 112.0 1.96   8 0.693 0.0175 110.0, 116.0 -1.21
NZW/LacJ m 111.0 3.45   8 1.22 0.0312 104.0, 115.0 -1.37
P/J f 114.0 1.25   8 0.441 0.0109 113.0, 116.0 -0.67
PL/J f 112.0 2.52   3 1.45 0.0224 110.0, 115.0 -1.21
PL/J m 111.0 2.3   5 1.03 0.0208 108.0, 113.0 -1.37
PWD/PhJ f 114.0 1.39   8 0.491 0.0122 112.0, 116.0 -0.67
PWD/PhJ m 110.0 5.15   8 1.82 0.0471 101.0, 115.0 -1.65
RIIIS/J f 124.0 4.14   8 1.46 0.0333 119.0, 133.0 2.05
RIIIS/J m 120.0 5.22   8 1.85 0.0436 114.0, 128.0 1.2
SJL/J f 116.0 1.52   6 0.619 0.0131 114.0, 118.0 -0.12
SJL/J m 115.0 2.99   4 1.49 0.026 112.0, 119.0 -0.23
SM/J f 117.0 1.89   7 0.714 0.0161 115.0, 120.0 0.15
SM/J m 115.0 3.17   9 1.06 0.0274 110.0, 120.0 -0.23
SWR/J f 121.0 9.73   9 3.24 0.0804 108.0, 138.0 1.23
SWR/J m 116.0 5.0   7 1.89 0.0429 109.0, 123.0 0.06
WSB/EiJ f 116.0 1.72   7 0.649 0.0148 114.0, 119.0 -0.12
WSB/EiJ m 117.0 4.47   7 1.69 0.0382 109.0, 122.0 0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 113.0 1.3837 115.7209 110.2791
129S1/SvImJ m 109.625 1.3837 112.3459 106.9041
A/J f 115.8333 1.5977 118.9751 112.6915
A/J m 119.6875 0.9784 121.6115 117.7635
AKR/J f 111.0 2.7673 116.4418 105.5582
AKR/J m 112.3333 2.2595 116.7765 107.8901
BALB/cByJ f 116.25 1.3837 118.9709 113.5291
BALB/cByJ m 114.5 1.3837 117.2209 111.7791
BTBR T+ Itpr3tf/J f 118.875 1.3837 121.5959 116.1541
BTBR T+ Itpr3tf/J m 119.5714 1.4792 122.4802 116.6627
BUB/BnJ f 123.8333 1.5977 126.9751 120.6915
BUB/BnJ m 114.5556 1.3045 117.1208 111.9903
C3H/HeJ f 113.875 1.3837 116.5959 111.1541
C3H/HeJ m 116.8571 1.4792 119.7659 113.9484
C57BL/10J f 114.0 1.3837 116.7209 111.2791
C57BL/10J m 122.4286 1.4792 125.3373 119.5198
C57BL/6J f 114.25 1.3837 116.9709 111.5291
C57BL/6J m 112.0 1.3837 114.7209 109.2791
C57BLKS/J f 122.75 1.3837 125.4709 120.0291
C57BLKS/J m 120.625 1.3837 123.3459 117.9041
C57BR/cdJ f 121.5 1.3837 124.2209 118.7791
C57BR/cdJ m 119.5 1.3837 122.2209 116.7791
C57L/J f 120.7143 1.4792 123.623 117.8055
C57L/J m 117.625 1.3837 120.3459 114.9041
CBA/J f 116.1429 1.4792 119.0516 113.2341
CBA/J m 113.3333 1.5977 116.4751 110.1915
DBA/2J f 115.1667 1.5977 118.3085 112.0249
DBA/2J m 117.7143 1.4792 120.623 114.8055
FVB/NJ f 119.375 1.3837 122.0959 116.6541
FVB/NJ m 117.25 1.3837 119.9709 114.5291
KK/HlJ f 114.375 1.3837 117.0959 111.6541
KK/HlJ m 115.375 1.3837 118.0959 112.6541
LP/J f 112.4286 1.4792 115.3373 109.5198
LP/J m 114.25 1.3837 116.9709 111.5291
MRL/MpJ f 117.375 1.3837 120.0959 114.6541
MRL/MpJ m 119.25 1.3837 121.9709 116.5291
NOD.B10Sn-H2b/J f 114.0 1.5977 117.1418 110.8582
NOD.B10Sn-H2b/J m 111.5 1.3837 114.2209 108.7791
NON/ShiLtJ f 119.875 1.3837 122.5959 117.1541
NON/ShiLtJ m 114.8571 1.4792 117.7659 111.9484
NZO/HlLtJ f 116.1429 1.4792 119.0516 113.2341
NZO/HlLtJ m 118.8333 1.5977 121.9751 115.6915
NZW/LacJ f 112.125 1.3837 114.8459 109.4041
NZW/LacJ m 110.75 1.3837 113.4709 108.0291
PL/J f 112.3333 2.2595 116.7765 107.8901
PL/J m 110.6 1.7502 114.0417 107.1583
PWD/PhJ f 113.75 1.3837 116.4709 111.0291
PWD/PhJ m 109.5 1.3837 112.2209 106.7791
RIIIS/J f 124.375 1.3837 127.0959 121.6541
RIIIS/J m 119.875 1.3837 122.5959 117.1541
SJL/J f 115.5 1.5977 118.6418 112.3582
SJL/J m 114.75 1.9568 118.5979 110.9021
SM/J f 117.2857 1.4792 120.1945 114.377
SM/J m 115.4444 1.3045 118.0097 112.8792
SWR/J f 121.0 1.3045 123.5653 118.4347
SWR/J m 116.4286 1.4792 119.3373 113.5198
WSB/EiJ f 116.4286 1.4792 119.3373 113.5198
WSB/EiJ m 117.0 1.4792 119.9088 114.0912


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 111.3125 0.9784 113.2365 109.3885
A/J both 117.7604 0.9367 119.6025 115.9184
AKR/J both 111.6667 1.7863 115.1793 108.154
BALB/cByJ both 115.375 0.9784 117.299 113.451
BTBR T+ Itpr3tf/J both 119.2232 1.0127 121.2147 117.2317
BUB/BnJ both 119.1944 1.0313 121.2225 117.1664
C3H/HeJ both 115.3661 1.0127 117.3576 113.3746
C57BL/10J both 118.2143 1.0127 120.2058 116.2228
C57BL/6J both 113.125 0.9784 115.049 111.201
C57BLKS/J both 121.6875 0.9784 123.6115 119.7635
C57BR/cdJ both 120.5 0.9784 122.424 118.576
C57L/J both 119.1696 1.0127 121.1611 117.1782
CBA/J both 114.7381 1.0887 116.8789 112.5973
DBA/2J both 116.4405 1.0887 118.5813 114.2997
FVB/NJ both 118.3125 0.9784 120.2365 116.3885
KK/HlJ both 114.875 0.9784 116.799 112.951
LP/J both 113.3393 1.0127 115.3308 111.3478
MRL/MpJ both 118.3125 0.9784 120.2365 116.3885
NOD.B10Sn-H2b/J both 112.75 1.0568 114.8281 110.6719
NON/ShiLtJ both 117.3661 1.0127 119.3576 115.3746
NZO/HlLtJ both 117.4881 1.0887 119.6289 115.3473
NZW/LacJ both 111.4375 0.9784 113.3615 109.5135
PL/J both 111.4667 1.429 114.2768 108.6565
PWD/PhJ both 111.625 0.9784 113.549 109.701
RIIIS/J both 122.125 0.9784 124.049 120.201
SJL/J both 115.125 1.2631 117.6088 112.6412
SM/J both 116.3651 0.9861 118.3042 114.4259
SWR/J both 118.7143 0.9861 120.6535 116.7751
WSB/EiJ both 116.7143 1.0459 118.7711 114.6575




  GWAS USING LINEAR MIXED MODELS