Project measure / variable:   Donahue2   femur_in

ID, description, units MPD:17221   femur_in   endosteal (inner) circumference, femoral mid-diaphysis   [mm]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure computed tomography
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue2 - endosteal (inner) circumference, femoral mid-diaphysis



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means3.19   mm 3.45   mm
Median of the strain means3.21   mm 3.45   mm
SD of the strain means± 0.340 ± 0.450
Coefficient of variation (CV)0.107 0.130
Min–max range of strain means2.58   –   3.75   mm 2.77   –   4.32   mm
Mean sample size per strain9.8   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.8894 3.8894 170.7439 < 0.0001
strain 9 28.8783 3.2087 140.8622 < 0.0001
sex:strain 9 1.2428 0.1381 6.0623 < 0.0001
Residuals 187 4.2597 0.0228


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 3.19 0.178   10 0.0563 0.0558 2.77, 3.35 0.0
129S1/SvImJ m 3.27 0.143   13 0.0396 0.0436 2.96, 3.51 -0.41
BALB/cJ f 3.22 0.0742   10 0.0235 0.0231 3.1, 3.35 0.09
BALB/cJ m 3.44 0.185   10 0.0584 0.0538 3.2, 3.79 -0.03
C3H/HeJ f 2.58 0.0559   9 0.0186 0.0217 2.46, 2.68 -1.79
C3H/HeJ m 2.92 0.117   11 0.0352 0.0399 2.69, 3.05 -1.18
C57BL/6J f 3.75 0.103   9 0.0342 0.0273 3.62, 3.9 1.65
C57BL/6J m 4.32 0.283   12 0.0817 0.0654 3.9, 4.87 1.93
C58/J f 3.42 0.159   9 0.053 0.0465 3.11, 3.61 0.68
C58/J m 3.68 0.208   10 0.0658 0.0565 3.45, 4.01 0.5
FVB/NJ f 3.49 0.169   11 0.0511 0.0485 3.25, 3.81 0.88
FVB/NJ m 3.87 0.0972   9 0.0324 0.0251 3.73, 4.03 0.93
NZB/BlNJ f 3.14 0.0864   11 0.0261 0.0275 3.05, 3.31 -0.14
NZB/BlNJ m 3.46 0.114   13 0.0315 0.0329 3.29, 3.65 0.02
PWK/PhJ f 2.79 0.1   12 0.029 0.036 2.63, 2.92 -1.17
PWK/PhJ m 2.77 0.194   10 0.0614 0.0701 2.53, 3.21 -1.52
SJL/J f 3.31 0.152   8 0.0537 0.0459 3.02, 3.53 0.36
SJL/J m 3.57 0.154   11 0.0465 0.0433 3.32, 3.76 0.26
SWR/J f 3.0 0.097   9 0.0323 0.0324 2.82, 3.12 -0.56
SWR/J m 3.23 0.124   10 0.0393 0.0385 3.04, 3.46 -0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 3.188 0.0477 3.2822 3.0938
129S1/SvImJ m 3.2731 0.0419 3.3557 3.1905
BALB/cJ f 3.22 0.0477 3.3142 3.1258
BALB/cJ m 3.435 0.0477 3.5292 3.3408
C3H/HeJ f 2.58 0.0503 2.6792 2.4808
C3H/HeJ m 2.92 0.0455 3.0098 2.8302
C57BL/6J f 3.7489 0.0503 3.8481 3.6496
C57BL/6J m 4.3242 0.0436 4.4101 4.2382
C58/J f 3.4211 0.0503 3.5204 3.3219
C58/J m 3.681 0.0477 3.7752 3.5868
FVB/NJ f 3.4936 0.0455 3.5834 3.4039
FVB/NJ m 3.8667 0.0503 3.9659 3.7674
NZB/BlNJ f 3.1409 0.0455 3.2307 3.0511
NZB/BlNJ m 3.4554 0.0419 3.538 3.3728
PWK/PhJ f 2.7892 0.0436 2.8751 2.7032
PWK/PhJ m 2.768 0.0477 2.8622 2.6738
SJL/J f 3.305 0.0534 3.4103 3.1997
SJL/J m 3.5664 0.0455 3.6561 3.4766
SWR/J f 2.9967 0.0503 3.0959 2.8974
SWR/J m 3.225 0.0477 3.3192 3.1308


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 3.2305 0.0317 3.2932 3.1679
BALB/cJ both 3.3275 0.0337 3.3941 3.2609
C3H/HeJ both 2.75 0.0339 2.8169 2.6831
C57BL/6J both 4.0365 0.0333 4.1022 3.9709
C58/J both 3.5511 0.0347 3.6195 3.4827
FVB/NJ both 3.6802 0.0339 3.7471 3.6132
NZB/BlNJ both 3.2981 0.0309 3.3591 3.2372
PWK/PhJ both 2.7786 0.0323 2.8423 2.7148
SJL/J both 3.4357 0.0351 3.5049 3.3665
SWR/J both 3.1108 0.0347 3.1792 3.0424




  GWAS USING LINEAR MIXED MODELS