Phenotype measure:   Donahue2   femur_thickness_L

ID, description, units MPD:17219   femur_thickness_L   cortical thickness of left femur, pQCT   [mm]
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure computed tomography
Ontology mappings

  STRAIN COMPARISON PLOT
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Donahue2 - cortical thickness of left femur, pQCT



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.224   mm 0.231   mm
Median of the strain means0.220   mm 0.220   mm
SD of the strain means± 0.0370 ± 0.0438
Coefficient of variation (CV)0.165 0.190
Min–max range of strain means0.188   –   0.314   mm 0.186   –   0.339   mm
Mean sample size per strain9.8   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0037 0.0037 26.862 < 0.0001
strain 9 0.2951 0.0328 235.1221 < 0.0001
sex:strain 9 0.0058 0.0006 4.6378 < 0.0001
Residuals 188 0.0262 0.0001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.226 0.0132   10 0.00417 0.0584 0.208, 0.248 0.05
129S1/SvImJ m 0.231 0.0148   14 0.00394 0.0639 0.208, 0.258 0.0
BALB/cJ f 0.245 0.00965   10 0.00305 0.0395 0.223, 0.259 0.56
BALB/cJ m 0.255 0.0164   10 0.0052 0.0643 0.23, 0.29 0.55
C3H/HeJ f 0.314 0.00809   9 0.0027 0.0257 0.303, 0.331 2.42
C3H/HeJ m 0.339 0.0156   11 0.00469 0.0459 0.32, 0.365 2.47
C57BL/6J f 0.192 0.00382   9 0.00127 0.0199 0.186, 0.2 -0.87
C57BL/6J m 0.208 0.00883   12 0.00255 0.0425 0.19, 0.221 -0.52
C58/J f 0.207 0.0103   9 0.00345 0.05 0.185, 0.221 -0.47
C58/J m 0.206 0.00802   10 0.00254 0.039 0.194, 0.216 -0.57
FVB/NJ f 0.213 0.00439   11 0.00132 0.0206 0.206, 0.218 -0.31
FVB/NJ m 0.201 0.00848   9 0.00283 0.0422 0.188, 0.211 -0.68
NZB/BlNJ f 0.235 0.0134   11 0.00405 0.057 0.206, 0.25 0.29
NZB/BlNJ m 0.245 0.0128   13 0.00356 0.0524 0.229, 0.268 0.32
PWK/PhJ f 0.194 0.0082   12 0.00237 0.0423 0.176, 0.204 -0.82
PWK/PhJ m 0.186 0.023   10 0.00726 0.123 0.135, 0.211 -1.02
SJL/J f 0.229 0.0126   8 0.00445 0.055 0.218, 0.25 0.13
SJL/J m 0.233 0.00865   11 0.00261 0.0372 0.218, 0.246 0.05
SWR/J f 0.188 0.00955   9 0.00318 0.0509 0.173, 0.199 -0.98
SWR/J m 0.204 0.00795   10 0.00251 0.039 0.193, 0.216 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2258 0.0037 0.2332 0.2184
129S1/SvImJ m 0.231 0.0032 0.2372 0.2248
BALB/cJ f 0.2446 0.0037 0.252 0.2372
BALB/cJ m 0.2554 0.0037 0.2628 0.248
C3H/HeJ f 0.3142 0.0039 0.322 0.3065
C3H/HeJ m 0.339 0.0036 0.346 0.332
C57BL/6J f 0.1919 0.0039 0.1997 0.1841
C57BL/6J m 0.2076 0.0034 0.2143 0.2009
C58/J f 0.2069 0.0039 0.2147 0.1991
C58/J m 0.2056 0.0037 0.213 0.1982
FVB/NJ f 0.2135 0.0036 0.2205 0.2064
FVB/NJ m 0.2012 0.0039 0.209 0.1935
NZB/BlNJ f 0.2355 0.0036 0.2425 0.2284
NZB/BlNJ m 0.2453 0.0033 0.2518 0.2388
PWK/PhJ f 0.1936 0.0034 0.2003 0.1869
PWK/PhJ m 0.186 0.0037 0.1934 0.1786
SJL/J f 0.2289 0.0042 0.2371 0.2206
SJL/J m 0.2326 0.0036 0.2397 0.2256
SWR/J f 0.1877 0.0039 0.1954 0.1799
SWR/J m 0.2036 0.0037 0.211 0.1962


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2284 0.0024 0.2332 0.2236
BALB/cJ both 0.25 0.0026 0.2552 0.2448
C3H/HeJ both 0.3266 0.0027 0.3318 0.3214
C57BL/6J both 0.1997 0.0026 0.2049 0.1946
C58/J both 0.2062 0.0027 0.2116 0.2009
FVB/NJ both 0.2073 0.0027 0.2126 0.2021
NZB/BlNJ both 0.2404 0.0024 0.2452 0.2356
PWK/PhJ both 0.1898 0.0025 0.1948 0.1848
SJL/J both 0.2308 0.0027 0.2362 0.2253
SWR/J both 0.1956 0.0027 0.201 0.1903




GWAS analysis not available: At least 12 strains are required