Project measure / variable:   Metten1   wobble_doseB_10min

ID, description, units MPD:16515   wobble_doseB_10min   erratic gait, 3.0 g/kg i.p.   [score]  10min after injection  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure behavior observation
Ontology mappings

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  STRAIN COMPARISON PLOT
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Metten1 - erratic gait, 3.0 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.603   score 0.479   score
Median of the strain means0.429   score 0.250   score
SD of the strain means± 0.732 ± 0.720
Coefficient of variation (CV)1.21 1.50
Min–max range of strain means0   –   2.00   score 0   –   2.25   score
Mean sample size per strain4.7   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4601 0.4601 0.8757 0.3529
strain 8 27.8966 3.4871 6.6363 < 0.0001
sex:strain 8 7.8741 0.9843 1.8731 0.0795
Residuals 65 34.1548 0.5255


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 0.0 0.0   3 0.0 0.0 -0.82
129P3/J m 0.0 0.0   3 0.0 0.0 -0.66
129S1/SvImJ f 0.0 0.0   4 0.0 0.0 -0.82
129S1/SvImJ m 0.0 0.0   3 0.0 0.0 -0.66
A/J f 0.5 0.577   4 0.289 1.15 -0.14
A/J m 0.25 0.5   4 0.25 2.0 -0.32
BALB/cByJ f 0.0 0.0   6 0.0 0.0 -0.82
BALB/cByJ m 0.143 0.378   7 0.143 2.65 -0.47
BTBR T+ Itpr3tf/J f 0.0 0.0   4 0.0 0.0 -0.82
BTBR T+ Itpr3tf/J m 0.0 0.0   4 0.0 0.0 -0.66
C3H/HeJ f 1.25 0.957   4 0.479 0.766 0.88
C3H/HeJ m 2.25 1.5   4 0.75 0.667 1.0, 4.0 2.46
C57BL/6J f 0.429 0.535   7 0.202 1.25 -0.24
C57BL/6J m 0.667 0.516   6 0.211 0.775 0.26
DBA/2J f 1.25 1.39   8 0.491 1.11 0.88
DBA/2J m 0.25 0.5   4 0.25 2.0 -0.32
FVB/NJ f 2.0 1.15   4 0.577 0.577 1.0, 3.0 1.91
FVB/NJ m 0.75 0.5   4 0.25 0.667 0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 0.0 0.4185 0.8358 -0.8358
129P3/J m 0.0 0.4185 0.8358 -0.8358
129S1/SvImJ f 0.0 0.3624 0.7238 -0.7238
129S1/SvImJ m 0.0 0.4185 0.8358 -0.8358
A/J f 0.5 0.3624 1.2238 -0.2238
A/J m 0.25 0.3624 0.9738 -0.4738
BALB/cByJ f 0.0 0.2959 0.591 -0.591
BALB/cByJ m 0.1429 0.274 0.69 -0.4043
BTBR T+ Itpr3tf/J f 0.0 0.3624 0.7238 -0.7238
BTBR T+ Itpr3tf/J m 0.0 0.3624 0.7238 -0.7238
C3H/HeJ f 1.25 0.3624 1.9738 0.5262
C3H/HeJ m 2.25 0.3624 2.9738 1.5262
C57BL/6J f 0.4286 0.274 0.9757 -0.1186
C57BL/6J m 0.6667 0.2959 1.2577 0.0756
DBA/2J f 1.25 0.2563 1.7618 0.7382
DBA/2J m 0.25 0.3624 0.9738 -0.4738
FVB/NJ f 2.0 0.3624 2.7238 1.2762
FVB/NJ m 0.75 0.3624 1.4738 0.0262


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 0.0 0.2959 0.591 -0.591
129S1/SvImJ both 0.0 0.2768 0.5528 -0.5528
A/J both 0.375 0.2563 0.8868 -0.1368
BALB/cByJ both 0.0714 0.2016 0.4741 -0.3313
BTBR T+ Itpr3tf/J both 0.0 0.2563 0.5118 -0.5118
C3H/HeJ both 1.75 0.2563 2.2618 1.2382
C57BL/6J both 0.5476 0.2016 0.9503 0.1449
DBA/2J both 0.75 0.2219 1.1933 0.3067
FVB/NJ both 1.375 0.2563 1.8868 0.8632




  GWAS USING LINEAR MIXED MODELS