Project measure / variable:   Metten1   splay_doseB_30min

ID, description, units MPD:16512   splay_doseB_30min   hindlimb splay, 3.0 g/kg i.p.   [score]  30min after  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure behavior observation
Ontology mappings

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  STRAIN COMPARISON PLOT
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Metten1 - hindlimb splay, 3.0 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means2.52   score 1.91   score
Median of the strain means2.25   score 2.00   score
SD of the strain means± 1.23 ± 1.10
Coefficient of variation (CV)0.488 0.576
Min–max range of strain means0.500   –   4.25   score 0   –   3.75   score
Mean sample size per strain4.6   mice 3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.613 3.613 1.2768 0.2629
strain 8 55.8894 6.9862 2.4689 0.0218
sex:strain 8 25.7832 3.2229 1.1389 0.3509
Residuals 61 172.6131 2.8297


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 3.67 1.53   3 0.882 0.417 2.0, 5.0 0.94
129P3/J m 2.0 2.65   3 1.53 1.32 0.08
129S1/SvImJ f 4.25 0.957   4 0.479 0.225 3.0, 5.0 1.41
129S1/SvImJ m 3.75 2.5   4 1.25 0.667 1.68
A/J f 2.25 1.5   4 0.75 0.667 -0.22
A/J m 2.0 0.816   4 0.408 0.408 1.0, 3.0 0.08
BALB/cByJ f 1.5 1.38   6 0.563 0.919 -0.83
BALB/cByJ m 1.57 2.15   7 0.812 1.37 -0.31
BTBR T+ Itpr3tf/J f 3.75 2.5   4 1.25 0.667 1.0
BTBR T+ Itpr3tf/J m 1.0 1.41   4 0.707 1.41 -0.83
C3H/HeJ f 3.0 0.816   4 0.408 0.272 2.0, 4.0 0.39
C3H/HeJ m 1.67 2.08   3 1.2 1.25 -0.22
C57BL/6J f 1.86 1.21   7 0.459 0.654 1.0, 4.0 -0.53
C57BL/6J m 3.17 1.17   6 0.477 0.369 2.0, 5.0 1.15
DBA/2J f 1.88 1.73   8 0.611 0.921 -0.52
DBA/2J m 2.0 2.65   3 1.53 1.32 0.08
FVB/NJ f 0.5 0.707   2   0.5 1.41 -1.64
FVB/NJ m 0.0 0.0   3 0.0 0.0 -1.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 3.6667 0.9712 5.6087 1.7246
129P3/J m 2.0 0.9712 3.942 0.058
129S1/SvImJ f 4.25 0.8411 5.9319 2.5681
129S1/SvImJ m 3.75 0.8411 5.4319 2.0681
A/J f 2.25 0.8411 3.9319 0.5681
A/J m 2.0 0.8411 3.6819 0.3181
BALB/cByJ f 1.5 0.6867 2.8732 0.1268
BALB/cByJ m 1.5714 0.6358 2.8428 0.3001
BTBR T+ Itpr3tf/J f 3.75 0.8411 5.4319 2.0681
BTBR T+ Itpr3tf/J m 1.0 0.8411 2.6819 -0.6819
C3H/HeJ f 3.0 0.8411 4.6819 1.3181
C3H/HeJ m 1.6667 0.9712 3.6087 -0.2754
C57BL/6J f 1.8571 0.6358 3.1285 0.5858
C57BL/6J m 3.1667 0.6867 4.5399 1.7934
DBA/2J f 1.875 0.5947 3.0643 0.6857
DBA/2J m 2.0 0.9712 3.942 0.058
FVB/NJ f 0.5 1.1895 2.8785 -1.8785
FVB/NJ m 0.0 0.9712 1.942 -1.942


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 2.8333 0.6867 4.2066 1.4601
129S1/SvImJ both 4.0 0.5947 5.1893 2.8107
A/J both 2.125 0.5947 3.3143 0.9357
BALB/cByJ both 1.5357 0.4679 2.4714 0.6
BTBR T+ Itpr3tf/J both 2.375 0.5947 3.5643 1.1857
C3H/HeJ both 2.3333 0.6424 3.6179 1.0488
C57BL/6J both 2.5119 0.4679 3.4476 1.5762
DBA/2J both 1.9375 0.5694 3.0761 0.7989
FVB/NJ both 0.25 0.7678 1.7853 -1.2853




  GWAS USING LINEAR MIXED MODELS