Project measure / variable:   Metten1   splay_doseA_30min


  STRAIN COMPARISON PLOT
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Metten1 - hindlimb splay, 2.75 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.02   score 1.33   score
Median of the strain means0.714   score 1.00   score
SD of the strain means± 0.671 ± 1.48
Coefficient of variation (CV)0.656 1.11
Min–max range of strain means0.250   –   2.25   score 0   –   4.75   score
Mean sample size per strain4.4   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.6212 2.6212 1.7591 0.1897
strain 8 62.2736 7.7842 5.2241 0.0001
sex:strain 8 22.9465 2.8683 1.925 0.0723
Residuals 61 90.8929 1.49


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 0.667 0.577   3 0.333 0.866 -0.53
129P3/J m 1.0 1.73   3 1.0 1.73 -0.22
129S1/SvImJ f 2.25 1.5   4 0.75 0.667 1.0, 4.0 1.83
129S1/SvImJ m 4.75 0.5   4 0.25 0.105 4.0, 5.0 2.3
A/J f 1.33 1.53   3 0.882 1.15 0.46
A/J m 1.0 0.0   4 0.0 0.0 1.0, 1.0 -0.22
BALB/cByJ f 0.333 0.816   6 0.333 2.45 -1.03
BALB/cByJ m 0.333 0.816   6 0.333 2.45 -0.67
BTBR T+ Itpr3tf/J f 1.75 2.36   4 1.18 1.35 1.08
BTBR T+ Itpr3tf/J m 1.0 0.816   4 0.408 0.816 -0.22
C3H/HeJ f 1.25 1.26   4 0.629 1.01 0.34
C3H/HeJ m 0.0 0.0   4 0.0 0.0 -0.9
C57BL/6J f 0.667 0.816   6 0.333 1.22 -0.53
C57BL/6J m 1.57 1.9   7 0.719 1.21 0.16
DBA/2J f 0.714 0.756   7 0.286 1.06 -0.46
DBA/2J m 2.33 2.52   3 1.45 1.08 0.67
FVB/NJ f 0.25 0.5   4 0.25 2.0 -1.15
FVB/NJ m 0.0 0.0   3 0.0 0.0 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 0.6667 0.7048 2.0759 -0.7426
129P3/J m 1.0 0.7048 2.4092 -0.4092
129S1/SvImJ f 2.25 0.6103 3.4704 1.0296
129S1/SvImJ m 4.75 0.6103 5.9704 3.5296
A/J f 1.3333 0.7048 2.7426 -0.0759
A/J m 1.0 0.6103 2.2204 -0.2204
BALB/cByJ f 0.3333 0.4983 1.3298 -0.6632
BALB/cByJ m 0.3333 0.4983 1.3298 -0.6632
BTBR T+ Itpr3tf/J f 1.75 0.6103 2.9704 0.5296
BTBR T+ Itpr3tf/J m 1.0 0.6103 2.2204 -0.2204
C3H/HeJ f 1.25 0.6103 2.4704 0.0296
C3H/HeJ m 0.0 0.6103 1.2204 -1.2204
C57BL/6J f 0.6667 0.4983 1.6632 -0.3298
C57BL/6J m 1.5714 0.4614 2.494 0.6489
DBA/2J f 0.7143 0.4614 1.6369 -0.2083
DBA/2J m 2.3333 0.7048 3.7426 0.9241
FVB/NJ f 0.25 0.6103 1.4704 -0.9704
FVB/NJ m 0.0 0.7048 1.4092 -1.4092


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 0.8333 0.4983 1.8298 -0.1632
129S1/SvImJ both 3.5 0.4316 4.363 2.637
A/J both 1.1667 0.4662 2.0988 0.2345
BALB/cByJ both 0.3333 0.3524 1.038 -0.3713
BTBR T+ Itpr3tf/J both 1.375 0.4316 2.238 0.512
C3H/HeJ both 0.625 0.4316 1.488 -0.238
C57BL/6J both 1.119 0.3396 1.798 0.4401
DBA/2J both 1.5238 0.4212 2.366 0.6816
FVB/NJ both 0.125 0.4662 1.0571 -0.8071




GWAS analysis not available: At least 12 strains are required