Project measure / variable:   Metten1   splay_doseA_10min


  STRAIN COMPARISON PLOT
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Metten1 - hindlimb splay, 2.75 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means2.56   score 2.59   score
Median of the strain means2.57   score 2.29   score
SD of the strain means± 1.23 ± 1.24
Coefficient of variation (CV)0.481 0.480
Min–max range of strain means0.500   –   5.00   score 0.250   –   4.33   score
Mean sample size per strain4.7   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0167 0.0167 0.0056 0.9407
strain 8 86.9143 10.8643 3.629 0.0016
sex:strain 8 4.3385 0.5423 0.1811 0.9927
Residuals 63 188.6071 2.9938


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 5.0 0.0   3 0.0 0.0 5.0, 5.0 1.98
129P3/J m 4.33 1.15   3 0.667 0.266 3.0, 5.0 1.4
129S1/SvImJ f 3.25 2.36   4 1.18 0.727 0.56
129S1/SvImJ m 4.0 2.0   4 1.0 0.5 1.0, 5.0 1.14
A/J f 3.0 0.816   4 0.408 0.272 2.0, 4.0 0.36
A/J m 2.25 1.26   4 0.629 0.559 1.0, 4.0 -0.27
BALB/cByJ f 1.57 2.07   7 0.782 1.32 -0.81
BALB/cByJ m 1.83 2.48   6 1.01 1.35 -0.61
BTBR T+ Itpr3tf/J f 2.75 2.63   4 1.31 0.956 0.15
BTBR T+ Itpr3tf/J m 3.33 2.89   3 1.67 0.866 0.6
C3H/HeJ f 2.25 1.71   4 0.854 0.759 -0.25
C3H/HeJ m 2.0 1.63   4 0.816 0.816 -0.47
C57BL/6J f 2.17 1.47   6 0.601 0.679 1.0, 5.0 -0.32
C57BL/6J m 2.29 1.6   7 0.606 0.702 -0.24
DBA/2J f 2.57 0.787   7 0.297 0.306 1.0, 3.0 0.01
DBA/2J m 3.0 2.0   3 1.15 0.667 1.0, 5.0 0.33
FVB/NJ f 0.5 0.577   4 0.289 1.15 -1.67
FVB/NJ m 0.25 0.5   4 0.25 2.0 -1.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 5.0 0.999 6.9963 3.0037
129P3/J m 4.3333 0.999 6.3296 2.3371
129S1/SvImJ f 3.25 0.8651 4.9788 1.5212
129S1/SvImJ m 4.0 0.8651 5.7288 2.2712
A/J f 3.0 0.8651 4.7288 1.2712
A/J m 2.25 0.8651 3.9788 0.5212
BALB/cByJ f 1.5714 0.654 2.8783 0.2646
BALB/cByJ m 1.8333 0.7064 3.2449 0.4218
BTBR T+ Itpr3tf/J f 2.75 0.8651 4.4788 1.0212
BTBR T+ Itpr3tf/J m 3.3333 0.999 5.3296 1.3371
C3H/HeJ f 2.25 0.8651 3.9788 0.5212
C3H/HeJ m 2.0 0.8651 3.7288 0.2712
C57BL/6J f 2.1667 0.7064 3.5782 0.7551
C57BL/6J m 2.2857 0.654 3.5926 0.9789
DBA/2J f 2.5714 0.654 3.8783 1.2646
DBA/2J m 3.0 0.999 4.9963 1.0037
FVB/NJ f 0.5 0.8651 2.2288 0.0
FVB/NJ m 0.25 0.8651 1.9788 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 4.6667 0.7064 6.0782 3.2551
129S1/SvImJ both 3.625 0.6117 4.8475 2.4025
A/J both 2.625 0.6117 3.8475 1.4025
BALB/cByJ both 1.7024 0.4813 2.6642 0.7406
BTBR T+ Itpr3tf/J both 3.0417 0.6608 4.3621 1.7213
C3H/HeJ both 2.125 0.6117 3.3475 0.9025
C57BL/6J both 2.2262 0.4813 3.188 1.2644
DBA/2J both 2.7857 0.597 3.9787 1.5927
FVB/NJ both 0.375 0.6117 1.5975 0.0




GWAS analysis not available: At least 12 strains are required