Project measure / variable:   Metten1   line_doseB_30min

ID, description, units MPD:16507   line_doseB_30min   line crossings, 3.0 g/kg i.p.   [n]  30min after  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 3.0 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means9.46   n 11.5   n
Median of the strain means8.43   n 9.67   n
SD of the strain means± 7.28 ± 7.13
Coefficient of variation (CV)0.769 0.619
Min–max range of strain means1.50   –   22.0   n 2.00   –   23.2   n
Mean sample size per strain4.6   mice 3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21.9083 21.9083 0.2236 0.638
strain 8 2413.7906 301.7238 3.0793 0.0056
sex:strain 8 777.9504 97.2438 0.9924 0.451
Residuals 61 5977.0595 97.9846


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 2.0 3.46   3 2.0 1.73 -1.02
129P3/J m 6.0 6.0   3 3.46 1.0 -0.78
129S1/SvImJ f 1.5 3.0   4 1.5 2.0 -1.09
129S1/SvImJ m 2.0 4.0   4 2.0 2.0 -1.34
A/J f 13.2 9.57   4 4.78 0.722 0.51
A/J m 23.2 3.59   4 1.8 0.155 18.0, 26.0 1.64
BALB/cByJ f 15.3 11.6   6 4.72 0.753 2.0, 34.0 0.8
BALB/cByJ m 9.29 8.4   7 3.18 0.905 -0.31
BTBR T+ Itpr3tf/J f 3.5 7.0   4 3.5 2.0 -0.82
BTBR T+ Itpr3tf/J m 16.2 12.3   4 6.17 0.759 2.0, 28.0 0.65
C3H/HeJ f 4.0 2.94   4 1.47 0.736 1.0, 8.0 -0.75
C3H/HeJ m 9.67 15.9   3 9.17 1.64 -0.26
C57BL/6J f 8.43 7.11   7 2.69 0.844 -0.14
C57BL/6J m 3.83 5.15   6 2.1 1.34 -1.08
DBA/2J f 15.2 16.8   8 5.94 1.1 0.79
DBA/2J m 15.3 15.5   3 8.95 1.01 0.53
FVB/NJ f 22.0 1.41   2   1.0 0.0643 21.0, 23.0 1.72
FVB/NJ m 18.3 13.7   3 7.88 0.745 6.0, 33.0 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 2.0 5.715 13.4279 0.0
129P3/J m 6.0 5.715 17.4279 0.0
129S1/SvImJ f 1.5 4.9494 11.3969 0.0
129S1/SvImJ m 2.0 4.9494 11.8969 0.0
A/J f 13.25 4.9494 23.1469 3.3531
A/J m 23.25 4.9494 33.1469 13.3531
BALB/cByJ f 15.3333 4.0411 23.4141 7.2526
BALB/cByJ m 9.2857 3.7414 16.767 1.8044
BTBR T+ Itpr3tf/J f 3.5 4.9494 13.3969 0.0
BTBR T+ Itpr3tf/J m 16.25 4.9494 26.1469 6.3531
C3H/HeJ f 4.0 4.9494 13.8969 0.0
C3H/HeJ m 9.6667 5.715 21.0946 0.0
C57BL/6J f 8.4286 3.7414 15.9099 0.9473
C57BL/6J m 3.8333 4.0411 11.9141 0.0
DBA/2J f 15.25 3.4997 22.2481 8.2519
DBA/2J m 15.3333 5.715 26.7612 3.9054
FVB/NJ f 22.0 6.9994 35.9963 8.0037
FVB/NJ m 18.3333 5.715 29.7612 6.9054


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 4.0 4.0411 12.0807 0.0
129S1/SvImJ both 1.75 3.4997 8.7481 0.0
A/J both 18.25 3.4997 25.2481 11.2519
BALB/cByJ both 12.3095 2.7536 17.8156 6.8034
BTBR T+ Itpr3tf/J both 9.875 3.4997 16.8731 2.8769
C3H/HeJ both 6.8333 3.7801 14.3922 0.0
C57BL/6J both 6.131 2.7536 11.6371 0.6249
DBA/2J both 15.2917 3.3507 21.9919 8.5915
FVB/NJ both 20.1667 4.5181 29.2012 11.1321




  GWAS USING LINEAR MIXED MODELS