Project measure / variable:   Metten1   line_doseB_10min


  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 3.0 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means5.35   n 7.02   n
Median of the strain means3.25   n 8.33   n
SD of the strain means± 5.04 ± 4.06
Coefficient of variation (CV)0.942 0.578
Min–max range of strain means0   –   15.2   n 0   –   13.2   n
Mean sample size per strain4.7   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 85.9101 85.9101 1.0393 0.3118
strain 8 1020.7019 127.5877 1.5434 0.1598
sex:strain 8 356.7702 44.5963 0.5395 0.8225
Residuals 65 5373.2202 82.6649


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 2.0 3.46   3 2.0 1.73 -0.66
129P3/J m 0.0 0.0   3 0.0 0.0 -1.73
129S1/SvImJ f 0.0 0.0   4 0.0 0.0 -1.06
129S1/SvImJ m 4.0 6.93   3 4.0 1.73 -0.74
A/J f 8.75 10.5   4 5.25 1.2 0.67
A/J m 2.75 4.86   4 2.43 1.77 -1.05
BALB/cByJ f 6.67 6.31   6 2.58 0.947 0.26
BALB/cByJ m 9.43 14.2   7 5.36 1.5 0.59
BTBR T+ Itpr3tf/J f 0.5 1.0   4 0.5 2.0 -0.96
BTBR T+ Itpr3tf/J m 8.5 9.85   4 4.92 1.16 0.36
C3H/HeJ f 3.25 2.99   4 1.49 0.919 -0.42
C3H/HeJ m 9.75 9.95   4 4.97 1.02 1.0, 24.0 0.67
C57BL/6J f 9.43 10.4   7 3.94 1.11 0.81
C57BL/6J m 8.33 8.89   6 3.63 1.07 0.32
DBA/2J f 2.38 2.62   8 0.925 1.1 -0.59
DBA/2J m 7.25 10.0   4 5.02 1.39 0.06
FVB/NJ f 15.2 13.7   4 6.86 0.9 1.0, 27.0 1.95
FVB/NJ m 13.2 17.0   4 8.5 1.28 1.52


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 2.0 5.2493 12.4835 -8.4835
129P3/J m 0.0 5.2493 10.4835 -10.4835
129S1/SvImJ f 0.0 4.546 9.079 -9.079
129S1/SvImJ m 4.0 5.2493 14.4835 -6.4835
A/J f 8.75 4.546 17.829 -0.329
A/J m 2.75 4.546 11.829 -6.329
BALB/cByJ f 6.6667 3.7118 14.0797 -0.7463
BALB/cByJ m 9.4286 3.4365 16.2917 2.5655
BTBR T+ Itpr3tf/J f 0.5 4.546 9.579 -8.579
BTBR T+ Itpr3tf/J m 8.5 4.546 17.579 -0.579
C3H/HeJ f 3.25 4.546 12.329 -5.829
C3H/HeJ m 9.75 4.546 18.829 0.671
C57BL/6J f 9.4286 3.4365 16.2917 2.5655
C57BL/6J m 8.3333 3.7118 15.7463 0.9203
DBA/2J f 2.375 3.2145 8.7948 -4.0448
DBA/2J m 7.25 4.546 16.329 -1.829
FVB/NJ f 15.25 4.546 24.329 6.171
FVB/NJ m 13.25 4.546 22.329 4.171


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 1.0 3.7118 8.413 -6.413
129S1/SvImJ both 2.0 3.4721 8.9342 -4.9342
A/J both 5.75 3.2145 12.1698 -0.6698
BALB/cByJ both 8.0476 2.5292 13.0987 2.9965
BTBR T+ Itpr3tf/J both 4.5 3.2145 10.9198 -1.9198
C3H/HeJ both 6.5 3.2145 12.9198 0.0802
C57BL/6J both 8.881 2.5292 13.932 3.8299
DBA/2J both 4.8125 2.7839 10.3722 -0.7472
FVB/NJ both 14.25 3.2145 20.6698 7.8302




GWAS analysis not available: At least 12 strains are required